The author investigated the activity of peptidases liberated by liver cells which suffered severe lesions, they made at the same time other diagnostic tests, sueh as: brom-sulfophtalic test, determination of the general protein level and evaluation of the percentagc of its fractions, as well as the Takata-Ara reaction test in 24 dogs. Above dogs were divided into threc groups: young healthy dogs, old healthy ones and dogs poisoned with the parasiticide preparation - CCl₄. The peptidases activity, expressed by the augmentation of the nitrogen remainder (RN) in young healthy dogs averages 40.70 mg. per cent, in old healthy dogs - 44.38 mg. per cent. In poisoned dogs this augmentation is much higher and amounts to 61.60 mg. per cent.
In 34 cows aged 4 to 10 years, the authors denoted the peptidase activity in the blood sera, the general level of the albumin and its fractions and performed the bromosulphthalic test. The group of healthy cows and groups with changes in the liver caused by the liver-fluke parasite have been separated. In cows with recent changes of the liver the peptidase activity is most intensive. The remaining samples give results typical for the hepatic inflammatory incidences. In cows with chronic changes the peptidase activity is similar to that characteristic for healthy cows.