Effects of excretions/secretions produced by larvae of Lucilia sericata on growth of poultry isolates Salmonella Enteritidis in vitro. Salmonella Enteritidis is a major serovar associated with food borne salmonellosis in humans. The increased level of antimicrobial resistance observed in Salmonella has become a public health concern. There is an urgent need for a new generation of antibiotics. The antibacterial properties of secretions collected from larvae of Lucilia sericata were examined in vitro. Studies revealed antibacterial activity of the larval excretion/secretion. The aim of this work was to define antibacterial potentials of maggot ES for the treatment of salmonellosis. In order to evaluate this, ES were screened for antibiotic properties against 10 pathogenic S. Enteritidis strains. The antibacterial activities of ES were tested using the agar well diffusion method and colony forming unit (CFU) assay. Based on the obtained results we can conclude that: (a) ES demonstrate bacteriostatic effect against Salmonella ,(b) the highest antibacterial activity was revealed at 250 mg/L.