A growing focus on nutrient transfers from agricultural lands to watershed has served to accelerate our understanding of the environmental consequences of pollutants management in agriculture. A complete watershed-scale agricultural non-point source (ANPS) pollution management issue would include policy instruments, management practices, economic stimulation institutions, practice approach, and modeling simulation, as well as integrating management and technology programs. Considering the continued impact of ANPS pollution to watershed environment is necessary. The policy, practice, simulation and economic mix instruments are refined based on information obtained through the review of existing literatures and different district action processes. The recommended management scenario involved integrated BMP strategies and payments for agriculture services followed by an incentive program, and practical options for water quality management. More precautionary, positive and group optimizing management is needed to quantitatively assess ANPS pollution control processes feasibility.