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1

Participation of cental adrenergic and cholinergic neurons in the development of the behavioural despair test in rats

100%
Plech A.
Acta Physiologica Polonica
|
1982
|
tom 33
|
nr 1-2
2

Effect of intrahippocampal injections of cooper salts on rat space memory

100%
Plech A.
Acta Neurobiologiae Experimentalis
|
1995
|
tom 55
|
nr 5
3
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Effect of pizotifen on convulsive effect of meso-tetra-4N-methyl-pirydyl-porphyrin [P] in mice

51%
Maksym B., Habdas J., Plech A.
Pestycydy
|
2008
|
nr 1-2
43-49
In this report we present effect of pizotifen, an antagonist of serotonin (5-hydroxytryptamine; 5-HT) receptors, on P-induced convulsions in mice. Experiments were conducted on male mice Balby. Convulsive effect P was determined using the following measures: percentage of mice with seizures, the number of seizure episodes/2 h, the latency time of the beginning P-induced seizure activity in mice and P-induced seizure activity of mice determined by score of Racine. Pretreatment mice with pizotifen (0.5 mg/kg ip) did not prevent convulsive effect P, applied ip at the dose of 50 μmol/kg ip (59.3 mg/kg) but significantly shortened the latency time of the beginning of P-induced seizure activity of mice. We conclude that central serotonin receptors are involved in the mechanism of P-induced convulsions.
4

Central beta-adrenergic receptors are involved in the mechanism of porphyrin-induced convulsive effect in mice

51%
Maksym B., Habdas J., Plech A.
Pestycydy
|
2005
|
nr 4
55-63
5

Nitric oxide mediates antinociceptive effect of leucopyrokinin active analog [2-8]-leucopyrokinin [[2-8]-LPK]

51%
Rykaczewska-Czerwinska M., Konopinska D., Plech A.
Pestycydy
|
2005
|
nr 4
65-70
6
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
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Effect of haloperidol [HAL] on leucopyrokinin [LPK]-induced biphasic hyper- and hypothermic effect in rats

51%
Rykaczewska-Czerwinska M., Konopinska D., Plech A.
Pestycydy
|
2008
|
nr 1-2
101-108
The aim of present study was to evaluate mechanisms involved in thermomodulatory effect LPK in rats.Experiments were performed on adult Wistar male rats. LPK was applied either intracerebroventricularly (icv), or intraperitoneally (ip) using the similar program and technique of experiments as in our previous study. We confirmed in this paper the results of our previous reports that icv administration LPK at the dose of 20 nmol induced evident significant rectal hypothermia, while lower dose LPK of 1 nmol icv exerted significant hyperthermic effect. Peripherally applied LPK at the range of doses 10-100 nmol/100 g ip displayed slight bimodal (hyperthermic and hypothermic) effect on rectal temperature. Prior administration of haloperidol, an antagonist of central dopamine receptors blocked both effects LPK applied either icv or ip. Obtained results indicate that both hypothermic and hyperthermic effects LPK are also modulated by central dopaminergic receptors.
7

Antinociceptive effect of insect hexapeptide, insect trypsin modulating oostatic factor [Neb-TMOF] in rats

51%
Plech A., Kuczer M., Szewczyk A., Konopinska D.
Pestycydy
|
2005
|
nr 1-2
5-13
8

Central thermoregulatory effect of insect neuropeptide leucopyrokinin [LPK] in rats

51%
Rykaczewska-Czerwinska M., Lombarska-Sliwinska D., Konopinska D., Plech A.
Pestycydy
|
2005
|
nr 4
125-131
9

Effect of insect neuropeptide leucopyrokinin [LPK] on rectal temperature in rats. Preliminary study

51%
Rykaczewska-Czerwinska M., Lombarska-Sliwinska D., Konopinska D., Plech A.
Pestycydy
|
2004
|
nr 3-4
10

Neurotoxic effect of copper salts in rats

51%
Plech A., Klimkiewicz T., Jakrzewska H.
Polish Journal of Environmental Studies
|
2000
|
tom 09
|
nr 4
Neurotoxic effects of copper ions after intraperitoneal (ip) and intracerebroventricular (icv) injections of CuSO4 • 5H2O and Cu(CH,COO) 2 • H2O at doses of 1-100 nmols icv and 0.1-100 pmols/kg ip was deter­mined in rats using two behavioural methods: exploratory and locomotor activity in an open field test and spatial memory in a water maze test. It has been found that higher doses of copper salts (100 nmols icv and 100 ^mols/kg ip) significantly decreased spatial memory of rats.
11

Study on convulsive effect of meso-tetra-4N-methylpirydyl-porphyrin [P] in rats

51%
Plech A., Maksym B., Habdas J.
Pestycydy
|
2004
|
nr 3-4
12

Behavioural effects of [2-8]-leucopyrokinin [[2-8]-LPK], an active, synthetic analogue of insect neuropeptide leucopyrokinin [LPK] in rats

51%
Rykaczewska-Czerwinska M., Konopinska D., Plech A.
Pestycydy
|
2004
|
nr 3-4
13

Phytosulfokines exert antinociceptive effect in rats

51%
Plech A., Konopinska D., Rykaczewska-Czerwinska M., Bahyrycz A.
Pestycydy
|
2004
|
nr 3-4
14

Chemiluminescence of meso-tetra-4N-methylpirydyl-porphyrin. Study in vitro

51%
Plech A., Maksym B., Klimkiewicz T., Habdas J.
Pestycydy
|
2004
|
nr 3-4
15
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
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Antinociceptive effect of poneratoxin [PoTX] in rats

45%
Rykaczewska-Czerwinska M., Radosz A., Konopinska D., Wrobel M., Plech A.
Pestycydy
|
2008
|
nr 1-2
135-141
Poneratoxin (molecular weight 2932) is a 25 amino acid neuropeptide, isolated from an ant venom. It affects excitability of nerve and muscle fibres by changing the kinetics of the voltage-dependent sodium channel. The aim of the study was to investigate the analgetic effect of synthetic poneratoxin (PoTX) in adult female Wistar rats. In the first part of the study the animals received PoTX intracerebroventricularly. The analgetic effect was evaluated by a tail immersion test. In the second part of the experiment the analgetic effect of PoTX was blocked with naloxone, an opioid receptors antagonist. The study showed that poneratoxin exerts the analgetic effect in rats and this effect is not mediated by central opioid system. Therefore it was concluded that other mechanism is resposible for the effect of PoTX.
16

Studies on central effects of [Lys1]-proctolin an analogue of proctolin (PR)

45%
Jedrusiak J., Plech A., Brus R., Sobotka W., Konopinska D.
Bulletin of the Polish Academy of Sciences. Biological Sciences
|
1991
|
tom 39
|
nr 1
17

Effects of intrahypothalamic injections of kainic acid on the bahaviour of rats

45%
Plech A., Szkilnik R., Zielinski M., Klis R., Herman Z. S.
Acta Physiologica Polonica
|
1981
|
tom 32
|
nr 2
18
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
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Antinociceptive effect of MAS MT in rats

45%
Rykaczewska-Czerwinska M., Radosz A., Szymanowska-Dziubasik K., Konopinska D., Plech A.
Pestycydy
|
2008
|
nr 3-4
139-146
MAS MT is a myotropic decapeptide isolated from Manduca sexta. This peptide exerts stimulatory effect on insects heart-beat frequency. The present study was undertaken in order to determine a probable antinociceptive effect in rats of native synthetic decapeptide, MAS MT-I and its two analogs, heptapeptides MAS MT-II and MAS MT-III. All these peptides were applied directly into the lateral brain ventricle (icv) at three doses: 10, 25 and 50 nmol. The analgesic (antinociceptive) effect was evaluated by a tail immersion test. It was found that two doses of MAS MT-I: 25 and 50 nmol induced significant antinociceptive effect, while MAS MT-II and MAS MT-III exert a less antinociceptive effect in comparison with native MAS MT-I. Prior icv administration of naloxone, an opioid antagonist weakly blocked MAS MT-I effect. We conclude that antinociceptive effect of MAS MT-I in rats is not mediated by central opioid system.
19

Central opioid receptors mediate antinociceptive effect in rats of insect hexapeptide - trypsin modulating oostatic factor [Neb-TMOF] and of its synthetic analogs

45%
Rykaczewska-Czerwinska M., Wrobel M., Kuczer M., Konopinska D., Plech A.
Pestycydy
|
2006
|
nr 1-2
21-27
20

Effects of clonidine and apomorphine on motor and exploratory activity in mice with frontal lobe lesions

45%
Plech A., Herman S., Bien E., Wierzbicki A., Opielka L.
Acta Physiologica Polonica
|
1978
|
tom 29
|
nr 6
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