This study evaluated interrelationships between iron, lead and cobalt content in African river prawn, Nile tilapia, sediment and water from Lake Asejire. In the six-month study, the metals were measured in samples collected monthly from three locations sited up-, mid- and downstream. Of all the sample types, iron and cobalt had the highest and lowest concentration, respectively. The relatively low concentration of iron and lead, in addition to non-detectable cobalt, in water samples shows that the lake water is free of iron, lead and cobalt pollution. The metals were also found at low levels in sediment, tilapia and prawn samples. The sediment serves as metal reservoir, since it contains greater metal concentration than water and the two aquatic organisms. The significant correlative relationship between iron and lead content in the water and sediment may be attributed to the role of sediment in releasing metals into the water column. Differences in the metal intake, requirement, and excretory mechanisms may be responsible for the negative correlation between the iron content of tilapia and river prawn. The fact that both organisms share the same sources of cobalt and lead, among other metals, may have contributed to the unitary correlation observed between cobalt and lead content in the organisms. Based on the findings of this study, the African river prawn, Nile tilapia, sediment and water of Lake Asejire can be considered free from iron, lead and cobalt pollution. Periodic metal content assessment is important to allow for adequate monitoring of the lake’s pollution status
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