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Long-distance safety of Marine search and rescue using drones can improve the searching speed. The current method is based on the long distance security classification of UAV.The degree of accuracy is low. A long-distance security modeling approach based on ArduinoMiniPro’s Marine search-and-rescue applying UAV is proposed. The method puts the fault tree analysis and relevant calculation for risk identification into use. The main factors affecting the safety of unmanned aerial vehicle (UAV) are long-distance searching and rescuing. The experimental results show that the proposed method can effectively build modeling for the long-distance safety of the Marine search and rescue UAV
Pre-operative treatment with recombinant human erythropoietin may improve aortic stenosis patients' condition, including anemia and/or cardiac dysfunction, for subjecting to aortic valve replacement. In this study, we tested this hypothesis in a mouse model of aortic stenosis. Adult male mice were subjected to either aortic stenosis created by aortic ligature or sham operation. Aortic stenosis for 4 weeks caused cardiac hypertrophy, pulmonary congestion and left ventricular dysfunction. It was associated with increased levels of tumor necrosis factor-a in serum and myocardium, and reduced levels of interleukin-10 in myocardium but not in serum. Mytocyte apoptosis rate, level of cleaved caspase 3, activity of nuclear factor-B and expression of p38-MAPK pathway were also elevated. Erythropoietin treatment increased hematocrit but did not prevent the development of cardiac hypertrophy. It, however, reduced the apoptosis, prevented the increases in tumor necrosis factor-, nuclear factor-B activation and phosphorylation of p38, and attenuated the increases in lung weight, the decreases in LVEF and LVFS, and the increases in LVDd and LVDs. In conclusion recombinant human erythropoietin has cardioprotective effects in maladaptive cardiac hypertrophy by inhibiting nuclear factor-B activation, phosphorylation of p38-MAPK pathway, and production of tumor necrosis factor-, together leading to a reduced apoptosis.
Reaumuria trigyna is a highly xeric small shrub and is a rare wild plant in Mediterranean areas. The flavonoid biosynthesis pathway in R. trigyna is strongly activated under salt stress, and many genes related to this pathway showed significant differences in transcript abundance under salt stress in a previous transcriptomic profiling analysis. The F3H gene, which encodes flavanone-3-hydroxylase, is an essential gene in the flavonoid biosynthetic pathway. The transcript levels of two F3H genes, RtF3H1 and RtF3H2, were increased in R. trigyna not only under salt stress but also under drought and cold stresses, and by abscisic acid. We measured the transcript levels of the two genes in different organs. There were high transcript levels of RtF3H1 in stems, and high transcript levels of RtF3H2 in roots and stems. The full-length cDNAs for RtF3H1 (Accession No. AB850638) and RtF3H2 (Accession No. AB850639) were cloned and were found to encode 353- and 358-amino-acid proteins, respectively. Escherichia coli overexpressing RtF3H1 or RtF3H2 showed better growth than that of a control E. coli line under various stress treatments. The survival rate of the recombinant E. coli strain expressing RtF3H2 was higher than that of the strain expressing RtF3H1 under salt and drought stresses.
Six kinds of municipal sludge samples were collected from wastewater treatment plants (WWTPs) from Guangzhou in southern China. Total concentration of Cu, Pb, Zn, Cr, Ni, Cd, and Mn in the sludge was determined, and used obtained values to appraise the degree of agricultural land pollution on the base of four pollution indixes. Results showed that the concentrations of the heavy metals Cu (4.567 mg/kg), Mn (1.844 mg/kg), Ni (148 mg/kg), Cr (121 mg/kg), and Cd (5.99 mg/kg) in S1 sludge were higher than that of the other sludges. In six sludge samples the concentrations of Mn, Zn, and Cu were highest, followed by Ni, Pb, and Cr. Cd had the lowest concentration. All were higher than those recorded in the background data for crop soils. With the exception of Cu and Cd from site S1, and Ni from sites S1, S2, and S5, all other metal concentrations conformed to permissible levels prescribed by the national application standard of acid soil in China (GB18918-2002). The geoaccumulation index (Igeo) assessment results indicate that there are serious risks in agricultural utilization for the existing Cu and Zn in these six kinds of sludges, especially the Igeo, which was 6.53 for Cu, 3.21 for Mn, 2.78 for Cd in the S1 sludge. The results of RI showed that sludge had high potential ecological risks, especially caused by Cd, which should give rise to widespread concerns. The potential ecological risk index (RI) of heavy metals in six sludge samples was ranked in the order of S1>S2>S4>S3>S5>S6.
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