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The effect of Propionibacterium granulosum, glucan and isoprinosine on the course of the infection of mice with Trichinella spiralis

100%

Golinska Z., Bany J., Szmigielski S., Petruczenko A.

Acta Parasitologica

1992

tom 37

nr 4

The effect of Propionibacterium granulosum, glucan and isoprinosine on the course of infection of B6C3F₁ mice with T. spiralis was studied. The worm burdens in the intestinal and muscle phases of the infection and the weight of spleens were determined. The intensity of the infection was reduced mainly in mice exposed to P. granulosum, most clearly after intraperitoneal injection on the day of infection; only slight increase in weight of spleens was found in these mice. On the contrary, after exposure of mice to P. acnes, the intensity of infection and the weight of spleens were increased. The effect of glucan was dose dependent. Low single dose caused a decrease in the number of intestinal and muscle forms of the parasite. Higher doses of glucan did not have any effect on the intensity of the infection. Various doses of isoprinosine did not affect the elimination of T. spiralis, and rather showed a tendency to increase the intensity of the infection.

The effect Propionibacterium granulosum, glucan and isoprinosine on the course of the infection of mice with Trichinella spiralis

100%

Golinska Z., Bany J., Szmigielski S., Petruczenko A.

Acta Parasitologica

1992

tom 37

nr 4

Ograniczanie wyników

2 Acta Parasitologica

2 Bany J.

2 Golinska Z.

2 Petruczenko A.

2 Szmigielski S.

2 1992

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The effect of Propionibacterium granulosum, glucan and isoprinosine on the course of the infection of mice with Trichinella spiralis

The effect Propionibacterium granulosum, glucan and isoprinosine on the course of the infection of mice with Trichinella spiralis