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Structure and dynamics of a DNA duplex containing single alpha-anomeric deoxyadenosine residue

100%

Bielecki L., Adamiak R. W.

Acta Biochimica Polonica

2001

tom 48

nr 1

Structure and dynamics of an undecamer DNA duplex containing a single a-anomeric deoxyadenosine residue placed in opposition to a thymidine unit have been studied using simulation of molecular dynamics in aqueous solution. Despite several noticeable deviations from the B-DNA duplex structure caused by the anomerisation, such as: West type puckering of the a-anomeric sugar, disrupted base stacking pattern and unstable duplex bending, the formation of a non-classical a-dA-T pair was observed. A novel way of visual presentation of trajectory data allowing high throughput screening of the conformational parameters is presented.

Pierwsza pelna sekwencja chromosomu eukariotycznego

80%

Bielecki L.

Biotechnologia

1993

nr 4

186-188

Ograniczanie wyników

1 Acta Biochimica Polonica

1 Biotechnologia

2 Bielecki L.

1 Adamiak R. W.

1 2001

1 1993

Wyniki wyszukiwania

Structure and dynamics of a DNA duplex containing single alpha-anomeric deoxyadenosine residue

Pierwsza pelna sekwencja chromosomu eukariotycznego