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The time-dependent alteration of anti-diuretic hormone system in hindlimb unloaded rats

100%

Chung S. Y., Kim S. K., Hong C. W., Oh K. W., Kim K. T., Sul J. G., Chung J. W., Kwon M. S.

Journal of Physiology and Pharmacology

2012

tom 63

nr 1

A proteomic analysis of the effect of MAPK pathway activation on L-glutamate-induced neuronal cell death

100%

Kang S., Kim E. Y., Bahn Y. J., Chung J. W., Lee D. H., Park S. G., Yoon T. S., Park B. C., Bae K. H.

Cellular and Molecular Biology Letters

2007

tom 12

nr 1

Oxidative stress has been implicated in the pathogenesis of neuronal degenerative diseases. It is also widely known that oxidative stress induces mitogen-activated protein kinase (MAPK) signaling cascades. In this study, we used proteomic analysis to investigate the role of the MAPK pathway in oxidative stress-induced neuronal cell death. The results demonstrated that several proteins, including eukaryotic translation elongation factor 2 (eEF2) and enolase I, showed a differential expression pattern during the neuronal cell death process, and this was MAPK pathway dependent. Several chaperone and cytoskeletal proteins including heat shock protein 70, calreticulin, vimentin, prolyl 4-hydroxylase β polypeptide, and transgelin 2 were up-or down-regulated, despite their expressions not depending on the MAPK pathway. These findings strongly suggest that the expressions of proteins which play protective roles are independent of the MAPK pathway. On the other hand, eEF2 and enolase I may be the downstream targets of the MAPK pathway.

Anti-inflammatory effects of simvastatin in nonsteroidal anti-inflammatory drugs-induced small bowel injury

81%

Kim E. K., Cho J. H., Jeong A. R., Kim E. J., Park D. K., Kwon K. A., Chung J. W., Kim K. O., Kim J. H., Kim J. H., Kim Y. J.

Journal of Physiology and Pharmacology

2017

tom 68

nr 1

Ograniczanie wyników

2 Journal of Physiology and Pharmacology

1 Cellular and Molecular Biology Letters

3 Chung J. W.

1 Bae K. H.

1 Bahn Y. J.

1 Cho J. H.

1 Chung S. Y.

1 Hong C. W.

1 Jeong A. R.

1 Kang S.

1 Kim E. J.

1 Kim E. K.

1 Kim E. Y.

1 Kim J. H.

1 Kim K. O.

1 Kim K. T.

1 Kim S. K.

1 Kim Y. J.

1 Kwon K. A.

1 Kwon M. S.

1 Lee D. H.

1 Oh K. W.

1 Park B. C.

1 Park D. K.

1 Park S. G.

1 Sul J. G.

1 Yoon T. S.

1 2017

1 2012

1 2007

Wyniki wyszukiwania

The time-dependent alteration of anti-diuretic hormone system in hindlimb unloaded rats

A proteomic analysis of the effect of MAPK pathway activation on L-glutamate-induced neuronal cell death

Anti-inflammatory effects of simvastatin in nonsteroidal anti-inflammatory drugs-induced small bowel injury