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Bilge keels are effective passive devices in mitigating the rolling motion, and the usage of them covers almost all the sea going vessels. This paper focuses on the viscous effect of the bilge keel, ignored the effect of the free surface and the effect of the ship hull, for the general viscous characteristic of the bilge keel. In order to investigate the viscous effect of the bilge keel on the total damping moment, a special 2 dimensional numerical model, which includes a submerged cylinder with and without bilge keels, is designed for the simulation of forced rolling. Three important factors such as bilge keels width, rolling periods, as well as maximal rolling angles are taken into account, and the viscous flow field around the cylinder is simulated by some codes based on the viscous method in different conditions, in which the three factors are coupled. Verification and validation based on the ITTC method are performed for the cylinder without bilge keels in the conditions of different rolling periods and maximal rolling angles. The primary calculation of damping moment induced by the cylinder with 0mm, 4mm, and 10mm width bilge keels shows some interesting results, and a systematic analysis is conducted. The analysis of the damping moment components suggests there is phase difference between the damping moment induced by the cylinder and the bilge keels, and when the bilge keels width reaches a special size, the total damping moment is mitigated. The calculation of the damping moments induced by the cylinder with some larger bilge keels are also performed, and the results suggest that, the damping moment induced by the bilge keels is increased rapidly and becomes the dominant part in the total damping moment while the width of the bilge keels are increased, but the damping moment induced by the cylinder is not changed significantly. Some illustration of the vortices formation and shedding is included, which is the mechanism of the damping moment caused by the bilge keels. The present work shows an interesting problem, and it is useful for the bilge keel design
To investigate how cognitive impairment is affected by the relief of bilateral carotid stenosis, chronic cerebral hypoperfusion was established through stenosis of the bilateral carotid common artery in adult Sprague-Dawley rats. Subsequently, the model rats received the intragastric placebo, donepezil (5 mg/kg), or surgery to relieve carotid stenosis after bilateral carotid common artery stenosis. After carotid stenosis was relieved, the cerebral blood flow values significantly increased, and P300 latency and escape latency in the Morris water-maze were significantly shortened. The concentrations of acetylcholine and norepinephrine in the dorsal hippocampus increased after carotid stenosis was relieved. Furthermore, P300 latency and escape latency were shortened in the relief-treated group compared to the drug-treated group, and acetylcholine levels in the relief-treated group were higher than the drug-treated group. No significant difference was found for the norepinephrine levels in the dorsal hippocampus between the relief-treated and drug-treated groups. Cognitive impairment can be significantly reduced by bilateral carotid stenosis relief, and the effect of relieving stenosis on cognitive dysfunction is superior to the effect of administering an acetylcholinesterase inhibitor.
Acquisition of inorganic phosphate (Pi) by plant roots is performed by phosphate transporters (PTs) located at the cytoplasmic membranes of epidermal cells and root hairs. A Triticum aestivum PT gene denoted as TaPT2 was functionally characterized in this study. TaPT2 is highly similar to TtPT2 and HvPT2, two PHT1 family genes in T. aestivum/Thinopyrum intermedium and barley, respectively. TaPT2 is 1,802 bp long at the cDNA level; it encodes a 525-amino acid polypeptide with a molecular weight of 57.5 kDa and an isoelectric point of 8.65. TaPT2 contains 12 conserved membrane-spanning domains and is transported to the cytosolic membrane after endoplasmic reticulum sorting. Functional complement analysis revealed that TaPT2 endowed Pi transporter activities in a yeast mutant that is defective in Pi uptake, with highaffinity Pi acquisition. TaPT2 transcripts were specifically detected in the roots. The transcripts were upregulated under Pi deprivation and downregulated under Pi sufficiency. These results suggest that TaPT2 expression is associated with external Pi concentration. Transgene analysis revealed that TaPT2 overexpression or knockdown did not regulate plant dry mass production, Pi acquisition, and photosynthetic capacity under Pi sufficiency. Under Pi deprivation, TaPT2 overexpression increased plant dry mass accumulation, total P content per plant, and photosynthetic efficiencies, whereas TaPT2 downregulation reduced plant dry mass, accumulative P amount, and photosynthetic parameters. These results collectively suggest that TaPT2 is a high-affinity PHT1 member that has important functions in mediating plant Pi uptake under Pi deprivation. TaPT2 can serve as a useful gene resource for the improvement of phosphorus use efficiency in cereals under Pi deprivation.
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