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Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
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Evaluation of calcium homeostasis in patients treated in Ternopil University Hospital for chronic obstructive pulmonary disease

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Oliynyk O., Doroshenko M., Slifirczyk A.
Health Problems of Civilization
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2016
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tom 10
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nr 4
Background. Osteoporosis is a significant problem in patients with advanced Chronic obstructive pulmonary disease. The etiology for the bone loss includes smoking, vitamin D deficiency,concomitant endocrine diseases, sedentary lifestyle, use of glucocorticoids. Osteoporosis is the pathology of calcium metabolism, thus the peculiarities of calcium homeostasis in Chronic obstructive pulmonary disease patients, depending on their bone mineral density were researched in the article. Material and methods. It was examined 86 patients with stage 3 Chronic obstructive pulmonary disease. Bone densitometry was performed on lumbar vertebrae using dual energy X-ray absorption scanner “Lunar”. Results. It was not find a significant difference in the duration of disease among patients suffering from 3rd stage CO PD with or without bone mass deficiency. All females with low bone mineral density had concomitant endocrine pathologies. It was established the increase of calcium content in sputum of patients with CO PD. Osteoporosis in patients with chronic obstructive pulmonary disease develops under influence of numerous factors, among which are: lack of physical activity, increase in calcium excretion with urine and sputum, low amount of calcium in diet, reduced exposure to sunlight, concomitant endocrine diseases in females and exposure to stressful situations, smoking, vitamin D deficiency. Conclusions. Osteoporosis in patients with chronic obstructive pulmonary disease develops under influence of numerous factors, among which are: lack of physical activity, increase in calcium excretion with urine and sputum, low amount of calcium in diet, reduced exposure to sunlight, concomitant endocrine diseases in females and exposure to stressful situations.
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Knowledge of parents of children with autism from Poland, Belarus and France concerning their child’s condition

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Slifirczyk A., Krajewska-Kulak E., Krukowska M., Maciorkowska E.
Health Problems of Civilization
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2019
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tom 13
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nr 2
Background. Autism is not only a problem for p eople with autism, but also for their entire families. Material and methods. 83 families were analysed, including 30 families from Poland, 25 families from Belarus and 28 families from France, an author’s questionnaire was used. Results. The majority of respondents were aware of the fact that autism can also be diagnosed in an adult person. Likewise, the notion of the autistic spectrum was known. While parents from Poland and France realised that a one-time diagnosis of the condition is insufficient, parents from Belarus more often chose the incorrect answer, and therefore they express the tendency to immediately start a therapy without additional consultations. All respondents from France chose the statement that treatment of autism should be started before the age of 3, which was confirmed by the majority of respondents from the other two countries. Polish parents barely considered the importance of preparation required to understand their child’s behaviour, whereas this aspect of the therapy was indicated by almost 90% of the respondents from the other two countries. Parents from Poland (69%) and Belarus (76%) were mostly convinced that autism cannot be cured completely. A different opinion was expressed by 42.9% of parents from France, who were convinced about it. The Poles most willingly used the Internet as a source of knowledge, while the French and Belarusians - a psychologist. A paediatrician was a preferred educator in Poland, in Belarus and France - a psychologist. Conclusions. The parents of autistic children, regardless of the country, showed a low level of knowledge about autism. The vast majority of respondents declared a desire to deepen their knowledge on autism, expressing their preference to have an individual conversation with an educator.
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Effectiveness of hemoperfusion in treatment of patients with non-biliary moderately severe pancreatitis

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Oliynyk O., Slifirczyk A., Pereviznyk B., Kushnarov W.
Health Problems of Civilization
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2018
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tom 12
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nr 3
Background. Acute pancreatitis morbidity has been rising annually all around the world. In case of acute necrotic pancreatitis, the mortality reaches 40% in the majority of hospitals. The therapy is effective if the efferent methods involve complex therapy of this disease. One such method is hemoperfusion, i.e. extracorporeal blood purification, which is widely used in toxicology. The authors of the article used hemoperfusion in a complex therapy in patients with severe acute pancreatitis. The following research presents an evaluation of the results of hemoperfusion used in a complex therapy of patients with acute pancreatitis. Material and methods. The study involved 38 patients with acute non-biliary moderately severe pancreatitis who were treated at an intensive care unit of Ternopil University Hospital in Ukraine. 18 patients were treated following the protocol for treatment of acute pancreatitis. In 20 patients, this treatment was additionally combined with hemoperfusion. We determined the levels of amylase, diastase, procalcitonin, bilirubin, malonic dialdehyde, and diene conjugates in blood serum and the level of leukocytes in the blood. Results. The levels of procalcitonin, amylase, bilirubin, leukocytes number, malonic dialdehyde, and diene conjugates were stabilised in patients of both groups, but in those who received hemoperfusion demonstrated much better results. These were manifested by significantly better levels of the amylase, bilirubin, creatinine, urea, procalcitonin, malonic dialdehyde, and diene conjugates in patients who received hemoperfusion (p< 0.005) than in the other group undergoing standard drug therapy. Conclusions. Hemoperfusion can be used as an effective method in the complex treatment of patients with acute pancreatitis.
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Meropenem resistance in intensive care units in Ukraine

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Oliynyk O., Slifirczyk A., Pereviznyk B.
Health Problems of Civilization
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2018
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tom 12
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nr 2
The article reviews the issue of antibiotic resistance of microorganisms to meropenem in intensive care units in Ukraine. An increase in meropenem inefficiency against microorganisms in intensive care units has been observed in the last years. The data analysis suggests a significant predominance of gram-negative flora: A. baumannii, Р. aeruginosa, К. pneumoniae, E. cloacae, E.coli. On average 30% of microorganisms are resistant to 5 and more basic antibiotics including meropenem. 40-80 % of the gram-negative flora in intensive care units in Ukraine are resistant to meropenem. This can be attributed to the free sale of antibiotics without prescription, patients’ self-treatment, inadequate antibiotic therapy, and failure to comply with sanitary norms on the part of intensive care staff. Microbiological diagnostics of infectious pathogens also needs improvement. Unless proper measures are taken within a few years, meropenem as an antibiotic is likely to disappear in Ukraine.
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Sickness rate and prevalence of thyroid cancer in a specific region of Ukraine 30 years after Chernobyl disaster

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Oliynyk O., Slifirczyk A., Potupalova T., Slobodian V.
Health Problems of Civilization
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2018
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tom 12
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nr 1
Background. The study aimed to determine the effect of iodine deficiency and increased radiation on morbidity of thyroid cancer in patients living in the Ternopil region of Ukraine. The task was solved by comparing the patients with thyroid cancer from the district areas with iodine deficiency and increased radiation with those coming from the regions with normal iodine content and a normal radioactive background. Material and methods. The area of the Ternopil region was divided into the following 1) the northern area, with sufficient iodine content in food, radiation background – 0.09 mcSv/h; 2) the central and western areas, endemic in terms of iodine content and increased background radiation (up to 0.13 mcSv/h); and 3) the southern area, with sufficient iodine but increased background radiation (up to 0.15 mcSv/h). To conduct the analysis and determine the sickness rate, the patients were grouped depending on sex and age. Results. The sickness rate and prevalence of thyroid cancer in males in 2016 were 4-6 times lower when compared to females in all areas. The sickness rate of the females in the areas with increased radiation turned out to be age-dependent with a 1.25-3.2 times increase when compared to the areas with normal conditions. In the areas of the increased background radiation and dietary iodine insufficiency, the sickness rate of females was 1.54-5.4 times higher than the index in the areas with normal conditions. Conclusions. The highest rates prevalence and sickness rate of thyroid cancer in Ternopil region of Ukraine were observed in women over 51 years. The prevalence was 2 times, and the sickness rate 3 times higher in women over 51 years in the areas with iodine deficiency and an increased radiation background when compared to those in the areas with normal iodine and radiation background.
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Treatment results evaluation in patients with severe sepsis, caused by severe traumatic brain injury at intensive care unit of Ternopil University Hospital

88%
Oliynyk O. V., Pereviznyk B. O., Slifirczyk A., Yemiashev O. V., Krasiy N. I.
Health Problems of Civilization
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2016
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tom 10
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nr 1
Background. Severe traumatic brain injury stays one of the main reasons of humans’ mortality until the age of 40. Ternopil University Hospital delivers medical care to the patients with neurosurgical pathology of Ternopil region, which is comprised of 1 107 000 citizens. Material and methods. In this paper we analyzed the treatment results of 301 patients with severe traumatic brain injury (STBI), who were treated at intensive care unit of Ternopil University Hospital during 2013-2014. Microbiological research and evaluation of results were accomplished according to generally accepted principles, based on the Bergey’s classification. Results. In 72 patients it was complicated by severe sepsis. The mortality rate in clinic reached 29.7% in 2013-2014, or equals 1.9 person per 100 000 of population. Among the intensive care unit patients with STBI, who had the surgery based on this pathological condition, sepsis developed in 23.9% of patients. Acute respiratory distress syndrome (ARDS), which complicated sepsis, was successfully cured in 73.3% of cases, by additional usage of traditional ventilation, kinesiotherapy, oxygen therapy and pulse therapy with glucocortisteroids (GS). 22.2% of patients obtained acute renal failure, 9.72% of patients were treated by implementing hemodialysis. Concomitant polytrauma was present in 23.9% of patients. Conclusions. Theusageof pulse therapy with glucocortisteroids additionally to traditional mechanical ventilation, kinesiotherapy, and oxygen therapy for the treatment of acute respiratory distress syndrome helps to improve the life expectancy of patients.
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Efekt placebo a skuteczność leczenia

88%
Tomaszewski M., Slifirczyk A., Wawryniuk P., Olchowik G., Tomaszewska M.
Człowiek i Zdrowie
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2013
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tom 07
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nr 4
Placebo jest zjawiskiem interdyscyplinarnym definiowanym obecnie jako nieaktywna farmakologicznie substancja lub zabieg, który nie posiada odpowiednich właściwości leczniczych. Mimo braku swoistego czynnika, stosowanie placebo przynosi pozytywne biologiczne skutki na organizm żywy. Pacjenci, którzy je przyjmują zgłaszają poprawę stanu zdrowia, uśmierzenie bólu oraz skrócenie czasu choroby. Poniższy artykuł zawiera aktualny stan wiedzy dotyczący właściwości, mechanizmów kontroli oraz skutków placebo.
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Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
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Burnout in the anaesthesiologists of western Ukraine and its possible causative factors

88%
Oliynyk O., Slifirczyk A., Prokop I., Oliynyk J., Venger O.
Health Problems of Civilization
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2019
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tom 13
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nr 2
Background. The paper deals with the problem of burnout among the anaesthesiologists of the Western Ukraine region and its causative factors. Burnout is characterized by mental and physical exhaustion owing to prolonged emotional stress. Material and methods. 105 anaesthesiologists were questioned as to the causes of job-related stress and their personal attitude to the job based on the Maslach Burnout Questionnaire. Questionnaire survey findings were compared in relation to the doctors’ practical experience. Results. Burnout symptoms were found to occur in 82% of anaesthesiologists with practical experience less than 5 years, and in 84% of doctors with practical experience above 20 years. These groups revealed high values of emotional burnout on the Maslach scale. Anaesthesiologists with 5-20 years of work experience revealed moderate levels of emotional burnout. High level of depersonalization was found in those with 5-20 years of work experience. For doctors who had less than 5 years and more than 20 years of work experience, depersonalization level was moderate. Conclusions. The group of anaesthesiologists with more than 20 years of work experience had the highest values of professional relationship reduction. The lowest value of this component of burnout was found in the young doctors with work experience of less than 5 years. About 80% of the doctors pointed out working intensity and insufficient salary as the main causes of work-related stress.
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Factors determining the psychometric assessment of patients after hip replacement surgery

76%
Michalczuk T., Slifirczyk A., Krajewska-Kulak E., Piszcz P., Galecka A., Kowalenko M.
Health Problems of Civilization
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2021
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tom 15
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nr 2
Background. The aim of this study was to investigate the influence of selected factors such as place of residence, education, age, duration of hospitalization and pain intensity before and after hip replacement surgery on the level of acceptance of the illness, on the subjective assessment of the patient’s state of health during surgery and on the level of pain and the ability to manage and reduce pain. Material and methods. The study included 181 patients diagnosed with hip joint degeneration and qualified for total hip replacement hospitalized in the Regional Specialist Hospital in Biała Podlaska, Poland. The study was conducted by means of a diagnostic survey with the use of a set of questionnaires: Acceptance of Illness Scale – AIS, WOMAC Scale, SF-36 Questionnaire, BPCQ Questionnaire. Results. More than half of the respondents (55.2%) were highly accepting of their condition. The level of acceptance was influenced by the place of residence, education, age, the intensity of pain after surgery and functional limitation. The overall assessment of the quality of life in the physical domain was – 62.9 points, with the worst scores for physical functioning and general health. Analysis with the WOMAC questionnaire showed that the majority of the subjects scored below 50 points on the functional limitation scale. All factors, except the level of pain before surgery, influenced the degree of functional limitation. Conclusions. Age, place of residence and education provided opportunities for pain control and the ability to reduce pain was perceived by those with longer hospital stays. Participants from cities had the highest quality of life. Education influenced the quality of life, which decreased with age and higher pain intensity. The better the quality of life, the higher the level of acceptance of illness, and vice versa.
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