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1

Probiotyki w produkcji drobiarskiej - ogólna charakterystyka oraz korzyści stosowania na przykładzie preparatu Lavipan

100%
Smialek M., Koncicki A.
Polskie Drobiarstwo
|
2016
|
nr 01
2

Probiotyki w produkcji drobiarskiej - ogólna charakterystyka oraz korzyści ze stosowania

100%
Smialek M., Koncicki A.
Polskie Drobiarstwo
|
2015
|
nr 12
3

Chlamydia psittaci - czy to nadal aktualny problem?

81%
Kowalczyk J., Smialek M., Koncicki A.
Polskie Drobiarstwo
|
2019
|
nr 07
4

Jak to, przecież były szczepione?! Cz.I

81%
Smialek M., Kowalczyk J., Konicicki A.
Polskie Drobiarstwo
|
2020
|
nr 06
5

Możliwości zastosowania żywieniowych dodatków funkcjonalnych do modulacji mechanizmów odpowiedzi immunologicznej u ptaków

81%
Tykalowski B., Smialek M., Pestka D.
Magazyn Weterynaryjny
|
2014
|
tom 23
|
nr 05 Choroby Ptaków - Monografia
6
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Sarkocystoza kaczek - przypadki kliniczne

81%
Smialek M., Stenzel T., Smialek A., Koncicki A.
Życie Weterynaryjne
|
2014
|
tom 89
|
nr 07
7

Wpływ fitoncydów na mikroflorę przewodu pokarmowego u drobiu

81%
Kowalczyk J., K. C. P. U. W.-M. w. O. O., Smialek M., Koncicki A.
Polskie Drobiarstwo
|
2019
|
nr 09
8

Ultrastructural studies on the nervous system in streptozotocine (STZ) - induced diabetes and experihental cerebral ischemia in the rat

81%
Piotrowski P., Gajkowska B., Olszewska H., Smialek M.
Acta Neurobiologiae Experimentalis
|
1999
|
tom 59
|
nr 3
9

Jak minimalizować stopień infekcji Campylobacter spp. na etapie produkcji pierwotnej, cz.II

81%
Smialek M., Kowalczyk J., Koncicki A.
Polskie Drobiarstwo
|
2021
|
nr 06
10

Znaczenie zakażeń bakteryjnych w patologii układu rozrodczego u drobiu grzebiącego

81%
Kowalczyk J., Smialek M., Tykalowski B., Koncicki A.
Polskie Drobiarstwo
|
2017
|
nr 02
11

Przyczyny występowania zakaźnego zapalenia mózgu i rdzenia kręgowego u kurcząt na przykładzie przypadku terenowego

81%
Smialek M., Smialek A., Tykalowski B., Koncicki A.
Magazyn Weterynaryjny
|
2014
|
tom 23
|
nr 05 Choroby Ptaków - Monografia
12

Wybrane zagadnienia z immunologii układu rozrodczego kury domowej

81%
Kowalczyk J., Smialek M., Tykalowski B., Koncicki A.
Medycyna Weterynaryjna
|
2016
|
tom 72
|
nr 11
In terms of its anatomy and functions, the reproductive system of birds is significantly different from the one found in mammals. It consists of only the left ovary and the left oviduct, which is constantly exposed to ascending infections because of its connection with the cloaca. Hence, the proper functioning of humoral and cell-mediated local immune mechanisms in this system is very important for maintaining its physiological functions. The expression of Toll-like receptors and the presence of T and B lymphocytes have been demonstrated in both the ovary and the oviduct of chickens. CD4⁺ T cell subpopulation is distributed mainly in the lamina propria of the oviduct, whereas in the submucous membrane and muscular layer these cells are found less frequently. CD8⁺ T lymphocytes are equally distributed in all abovementioned layers of the oviduct wall. IgY⁺ B cells are distributed among the epithelial cells, and they are closely connected with the glandular tissue of the oviduct, mainly in the infundibulum, magnum, and uterus regions. IgA⁺ and IgM⁺ B cells are present in the entire oviduct, but mainly in the glandular tissue of the magnum. IgY⁺ B cells have not been detected in the ovary, unlike IgM⁺ B cells, which have been demonstrated in the ovary stroma. In addition to T and B cells, antigen-presenting cells are present in the follicle wall and in the oviduct. During the early stages of reproductive maturation, a decrease in the number of immunocompetent cells is observed in the reproductive system, and the local immnosuppression increases the susceptibility of birds to Salmonella Enteritidis infections. The number of T and B lymphocytes in the mucous membrane of the oviduct decreases with age, which facilitates infections of the reproductive system. Additionally, the local immune mechanisms of the reproductive system in birds involve the transfer of protective IgY, IgA and IgM maternal antibodies to hatching eggs. The local immune mechanisms of the reproductive tract are responsible for preventing infections that disturb the physiological functions of the reproductive system and for protecting eggs from contamination.
13

Przypadek kliniczny IBD jako konsekwencja złego szczepienia w ZWD

81%
Smialek M., Smialek A., Heffa P., Koncicki A.
Polskie Drobiarstwo
|
2018
|
nr 10
14

Dogadajmy się z sąsiadem

81%
Smialek M., Kowalczyk J., Koncicki A.
Polskie Drobiarstwo
|
2020
|
nr 02
15
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Local immunity of the respiratory mucosal system in chickens and turkeys

81%
Smialek M., Tykalowski B., Stenzel T., Koncicki A.
Polish Journal of Veterinary Sciences
|
2011
|
tom 14
|
nr 2
This review article presents fundamental mechanisms of the local mucosal immunity in selected regions of the respiratory tract in healthy birds and in some pathological conditions. The respiratory system, whose mucosa come into direct contact with microorganisms contaminating inhaled air, has some associated structures, such as Harderian gland (HG), conjunctive-associated lymphoid tissue (CALT) and paranasal glands (PG), whose participation in local mechanisms of the mucosal immunity has been corroborated by numerous scientific studies. The nasal mucosa, with structured clusters of lymphoid tissue (NALT – nasal-associated lymphoid tissue) is the first to come into contact with microorganisms which contaminate inhaled air. Lymphoid nodules, made up of B cells with frequently developed germinal centres (GC), surrounded by a coat of CD4+ cells, are the major NALT structures in chickens, whereas CD8+ cells are situated in the epithelium and in the lamina propria of the nasal cavity mucosa. Studies into respiratory system infections (e.g. Mycoplasma gallisepticum) have shown the reactivity of the tracheal mucosa to infection, despite a lack of essential lymphoid tissue. Bronchus-associated lymphoid tissue (BALT) takes part in bronchial immune processes and its structure, topography and ability to perform defensive function in birds is largely age-dependent. Mature BALT is covered by a delicate layer of epithelial cells, called follicle-associated epithelium (FAE). Germinal centres (GC), surrounded by CD4+ cells are developed in most mature BALT nodules, while CD8+ lymphocytes are dispersed among lymphoid nodules and in the epithelium, and they are rarely present in GC. Macrophages make up the first line of defence mechanisms through which the host rapidly responds to microorganisms and their products in the respiratory mucosal system. Another very important element are polymorphonuclear cells, with heterophils being the most important of them. Phagocytic cells obtained from lung lavages in birds are referred to as FARM (free avian respiratory macrophages). Their number in chickens and turkeys is estimated to be 20 times lower than that in mice and rats, which indicates a deficit in the first-line of defence in the birds’ respiratory system. There are numerous B cells and antibody secreting cells (ASC) present throughout the respiratory system in birds. Their role comes down to perform antigen-specific protection by producing antibodies (IgM, IgY or IgA class) as a result of contact with pathogenic factors.
16
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

The perspective of immunoprophylaxis and selected immunological issues in the course of the turkey rhinotracheitis

81%
Smialek M., Tykalowski B., Stenzel T., Koncicki A.
Polish Journal of Veterinary Sciences
|
2012
|
tom 15
|
nr 1
This review article presents immunological issues in the course of the turkey rhinotracheitis (TRT) emphasizing local immunity mechanisms, both humoral and cell-mediated, in the upper respiratory system. Studies on the influence of the humoral immunity in the course of infection and vaccinations against TRT have revealed many times the absence of correlation between the titre of specific IgY anti-aMPV (avian Metapneumovirus) antibodies in the serum and in the upper respiratory washings and the immunity against the occurrence of the clinical form of the TRT. Considering the above, T cells are increasingly often regarded as the main factor involved in the upper respiratory immunity against the TRT. However, there have been just a few reports on the role of the T cells in the local immunity processes in the infection with aMPV in turkeys. Additionally, studies of the T-cell-associated immunity against the TRT have given ambiguous results. Immunoprophylaxis issues against the aMPV infections are a significant part of the work where the authors confront current vaccination programmes against the perspectives of use of the future vaccines against the TRT. Future vaccines should face the following criteria: absence of the risk of immunosuppressive effect and reversion of vaccine strains virulence, ease-of-use combined with the possibility of administration of the vaccine to the large numbers of turkeys. The leading role in future vaccination programs for birds against the TRT is likely to be played by the in ovo technique and the recombinant vaccines. Great hopes are also linked with the development of subunit vaccines against the aMPV.
17

Zakażenia drobiu bakteriami z rodzaju Campylobacter oraz ich znaczenie dla zdrowia publicznego

81%
Smialek M., Kowalczyk J., Koncicki A.
Polskie Drobiarstwo
|
2017
|
nr 11
18

Kontaktowe zapalenie skóry oraz cellulitis u indyków

81%
Smialek M., Tykalowski B., Stenzel T., Koncicki A.
Magazyn Weterynaryjny
|
2011
|
tom 20
|
nr 05 Choroby Ptaków - Monografia
19
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Practical aspects of estimation of optimal time for vaccination of chicken against IBD with use of „Deventer formula”

81%
Smialek M., Smialek A., Koncicki A.
Polish Journal of Veterinary Sciences
|
2016
|
tom 19
|
nr 2
One of the most commonly applied vaccination strategies against chicken infectious bursal disease (IBD) is the use of live vaccines at the optimal time estimated with the use of Deventer formula. The present study investigated the impact of different factors on maternally derived antibodies decline and therefore on the vaccination schedule against IBD. Our results suggest that blood collection from birds older than 3 days is more reliable in order to estimate the optimal date for IBD vaccination, due to disturbances in yolk sac resorption early after hatch.
20

Czy szczepienie indyków przeciwko chorobie Mareka jest uzasadnione?

81%
Smialek M., Kowalczyk J., Smialek A., Koncicki A.
Polskie Drobiarstwo
|
2017
|
nr 07
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