Our group studies the epigenetic mechanisms associated to psychiatric (e.g. PTSD, depression and schizophrenia), neurodegenerative (e.g. Alzheimer’s disease) and autoimmune (e.g. multiple sclerosis) diseases. We search for biomarkers and therapeutic targets for diagnosis, prognosis and treatment of such devastating diseases. Our findings provide a novel molecular insight to the mechanisms underlying fear extinction and cognitive impairment and highlight the potential of targeting the IGF2/IGFBP7 pathway as therapeutic avenue to treat some neuropsychiatric diseases. Furthermore, SERT clustering in peripheral lymphocytes can be used to identify patient response to antidepressant therapy
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