Wyniki wyszukiwania

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Selenium, glutathione and glutathione peroxidases in blood of patients with chronic liver diseases

100%

Czuczejko J., Zachara B. A., Staubach-Topczewska E., Halota W., Kedziora J.

Acta Biochimica Polonica

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2003

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tom 50

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nr 4

Disturbances in the antioxidant system could play a role in pathogenesis of chronic liver disease. The aim of our study was to evaluate the levels/activities of antioxidants in blood of patients with chronic liver disease. We estimated selenium and glutathione concentrations and glutathione peroxidase activities in blood of 59 patients with chronic hepatitis B or C virus infection (group 1) and 64 patients with alcoholic, autoimmune or cryptogenic chronic liver disease (group 2). The results were compared with 50 healthy controls. Whole blood and plasma selenium and red cell glutathione concentrations were significantly lower in the patients compared with the controls. Red cell glutathione peroxidase activity was slightly reduced in both subgroups of group 1 and in group 2 with normal alanine aminotransferase values. Plasma glutathione peroxidase activity was slightly but significantly higher in patients with elevated aminotransferase values.The findings suggest that disturbances in antioxidant parameters in blood of patients with chronic liver disease may be the cause of the peroxidative damage of cells.

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Effect of quinapril and perndopril therapies on the glutathione concentration and the glutathione peroxidase and glutathione-S-transferase activities in aged patients with arterial hypertension ( a preliminary study)

86%

Kotlowska K., Szewczyk-Golec K., Czuczejko J., Pawluk H., Kedziora-Kornatowska K., Motyl J., Kedziora J.

Acta Biochimica Polonica

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2003

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tom 50

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nr Supplement 1

3

The effect of quinapril and perindopril therapies on the level of malondialdehyde and superoxide dismutase and catalase activities in erythrocytes of geriatric patients with essential hypertension

86%

Czuczejko J., Szewczyk-Golec K., Kedziora-Kornatowska K., Motyl J., Pawluk H., Kotlowska K., Kedziora J.

Acta Biochimica Polonica

|

2003

|

tom 50

|

nr Supplement 1

Ograniczanie wyników

3 Acta Biochimica Polonica

3 Czuczejko J.

3 Kedziora J.

2 Kedziora-Kornatowska K.

2 Kotlowska K.

2 Motyl J.

2 Pawluk H.

2 Szewczyk-Golec K.

1 Halota W.

1 Staubach-Topczewska E.

1 Zachara B. A.

3 2003

Selenium, glutathione and glutathione peroxidases in blood of patients with chronic liver diseases

Effect of quinapril and perndopril therapies on the glutathione concentration and the glutathione peroxidase and glutathione-S-transferase activities in aged patients with arterial hypertension ( a preliminary study)

The effect of quinapril and perindopril therapies on the level of malondialdehyde and superoxide dismutase and catalase activities in erythrocytes of geriatric patients with essential hypertension