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Computed tomographic, ultrasonographic and radiographic features of caprine congenital goiter and normal thyroid gland in 2-month-old goats

100%

Pankowski F., Bartyzel B. J.

Folia Pomeranae Universitatis Technologiae Stetinensis. Agricultura, Alimentaria, Piscaria et Zootechnica

2023

tom 65

nr 1(366)

Hamartoma: a rare developmental disorder

61%

Bartyzel B. J., Max A., Gruszczynska J., Sobczak-Filipiak M., Mecik-Kronenberg T., Pankowski F.

Medycyna Weterynaryjna

2017

tom 73

nr 04

Hamartoma is a developmental disorder of various body parts and organs. It is characterized by a non-neoplastic growth of tissue with an uneven distribution and proportion of individual cells. Lesions progress for several years, but usually do not give clinical symptoms, and do not undergo malignant transformation. They occur alone or coexist with other defects, sometimes forming a characteristic clinical picture of a syndrome of congenital defects. Mutations in genes, such as PTEN, GLI3, SDH B/D, PIK3CA and ACT1, cause a dysfunction of the tumor suppressor gene and result in an increased neoplastic transformation. Hamartoma is a lesion between developmental disorders and benign tumors, which occurs frequently in humans, but is very rare in domestic animals. In a histopathological examination, however, it is diagnosed relatively often. In the veterinary literature, both hamartoma and choristoma are attributed mostly to errors in embryogenesis and are not considered as preneoplastic lesions.

Ograniczanie wyników

1 Folia Pomeranae Universitatis Technologiae Stetinensis. Agricultura, Alimentaria, Piscaria et Zootechnica

1 Medycyna Weterynaryjna

2 Bartyzel B. J.

2 Pankowski F.

1 Gruszczynska J.

1 Max A.

1 Mecik-Kronenberg T.

1 Sobczak-Filipiak M.

1 2023

1 2017

Wyniki wyszukiwania

Computed tomographic, ultrasonographic and radiographic features of caprine congenital goiter and normal thyroid gland in 2-month-old goats

Hamartoma: a rare developmental disorder