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Efficacy of Saccharomyces boulardii as a probiotic in dogs with lincomycin induced diarrhoea

100%

Aktas M. S., Borku M. K., Ozkanlar Y.

Bulletin of the Veterinary Institute in Puławy

2007

tom 51

nr 3

Twenty-four dogs were divided into three equal groups. Lincomycin was administered intramuscularly to all groups. However, group II was given S. boulardii after lincomycin induced diarrhoea occurred, and in group III, lincomycin was administered together with S. boulardii. Lincomycin caused diarrhoea in groups I (in 7.8±1.6 d) and II (in 6.9±2 d), but it did not cause diarrhoea in group III. The durations of diarrhoea were significantly different (P<0.05) between group I (6.5±1.2 d) and group II (2.9±0.4 d). The total short chain fatty acid (TSCFA) level was significantly lower (P<0.001) compared with their baselines in groups I and II at the time of the diarrhoeas' onset and cessation. Additionally, there were differences between groups at the time of diarrhoea cessation and 1 week after the treatment (P<0.05). In conclusion, lincomycin decreased TSCFAs causing diarrhoea in the dogs when given alone, and S. boulardii was effective in treating lincomycin induced diarrhoea and to prevent the occurrence of diarrhoea when given together with lincomycin.

Effect of dexamethasone on the treatment of lung oedema induced by oleic acid in dogs

64%

Borku M. K., Ozkanlar Y., Saglam Y. S., Hayirli A., Hanedan B., Karakurum C., Aktas M. S., Kirmizigul A. H.

Bulletin of the Veterinary Institute in Puławy

2007

tom 51

nr 3

The therapeutic effect of 1 mg/kg of dexamethasone on lung oedema and respiratory distress induced by 0.08 mg/kg of oleic acid (OA) in dogs was investigated into 8 dogs. One hour after OA injection, blood pH, HCO₃, pO₂, O₂Hb, and heart rate decreased, whereas COHb, pCO₂, temperature, and respiration rate increased. Lung oedema was confirmed histopathologically in a dog from the control group who died. Blood pH, COHb, temperature, and respiration rate returned to normal values after administration of dexamethasone. It has been determined that respiratory distress and lung oedema cause important changes in blood gases and the administration of a single dose of 1 mg/kg of dexamethasone is effective in the treatment of lung oedema and respiratory distress induced in dogs by OA.

Ograniczanie wyników

2 Bulletin of the Veterinary Institute in Puławy

2 Aktas M. S.

2 Borku M. K.

2 Ozkanlar Y.

1 Hanedan B.

1 Hayirli A.

1 Karakurum C.

1 Kirmizigul A. H.

1 Saglam Y. S.

2 2007

Wyniki wyszukiwania

Efficacy of Saccharomyces boulardii as a probiotic in dogs with lincomycin induced diarrhoea

Effect of dexamethasone on the treatment of lung oedema induced by oleic acid in dogs