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Structural studies of cysteine proteases and their inhibitors

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Grzonka Z., Jankowska E., Kasprzykowski F., Kasprzykowska R., Lankiewicz L., Wiczk W., Wieczerzak E., Ciarkowski J., Drabik P., Janowski R., Kozak M., Jaskolski M., Grubb A.

Acta Biochimica Polonica

2001

tom 48

nr 1

Cysteine proteases (CPs) are responsible for many biochemical processes occurring in living organisms and they have been implicated in the development and progression of several diseases that involve abnormal protein turnover. The activity of CPs is regulated among others by their specific inhibitors: cystatins. The main aim of this review is to discuss the structure-activity relationships of cysteine proteases and cystatins, as well as of some synthetic inhibitors of cysteine proteases structurally based on the binding fragments of cystatins.

Ograniczanie wyników

1 Acta Biochimica Polonica

1 Ciarkowski J.

1 Drabik P.

1 Grubb A.

1 Grzonka Z.

1 Jankowska E.

1 Janowski R.

1 Jaskolski M.

1 Kasprzykowska R.

1 Kasprzykowski F.

1 Kozak M.

1 Lankiewicz L.

1 Wiczk W.

1 Wieczerzak E.

1 2001

Wyniki wyszukiwania

Structural studies of cysteine proteases and their inhibitors