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1

Skutecznosc leczenia klinicznych postaci mastitis przy zastosowaniu niektorych preparatow i polaczen antybiotykow z kwasem acetylosalicylowym lub chlormetyna

100%
Malinowski E., Klossowska A., Szalbierz M., Markiewicz H.
Medycyna Weterynaryjna
|
1993
|
tom 49
|
nr 08
354-356
The investigations were carried out in one farm during 3 years. Clinical mastitis was treated with the following drugs: 1) Pathozone (55 quarters), 2) Nafpenzal MC (69 quarters), 3) Vetimast (24 quarters), 4) Masticort PS (32 quarters), 5) Syntarpen (78 quarters), 6) a water solution of procainic penicillin (2 min iu) with 1,0 g of streptomycin in 100 ml of distilled water (311 quarters), 7) a water solution of 1,2 ml iu of procainic penicillin (270 quarters), 8) a water solution of streptomycin 1,0 g (16 quarters), 9) a water solution of ampicillin 0,5 g (11 guarters), 10) penicillin procainic (600 000 iu) with acetylosalicylic acid (200 mg) in a 5.0% glucose solution (105 quarters), 11) penicillin (600 000 iu) with chlormethine (0,2 mg) in a 5,0% glucose solution (157 quarters), 12) oxytetracyline (1,0 g) with acetylosalicylic acid (200 mg) in a 5,0% glucose solution (79 quarters), 13) oxytetracyline (1,0 g) with chlormethine (0,2 mg) in a 5,0% glucose solution (68 quarters), 14) neomycin (0,5 g) with acetylosalicylic acid (200 mg) in a 5,0% glucose solution (36 quarters), 15) erytromycin (0,6 g) with chlormethine (0,2 mg) (13 quarters). Pathozone and combinations of antibiotics with acetylosalicylic acid, chlormethine and glucose were intramammary infused only once. Other drugs were applied three times every 24 hr. The effect of therapy established on clinical examinations, bacteriological tests and cell counts in milk was evaluated on the 14th day after treatment. The percentage of cured quarters was as follows: 1 — 65,5%, 2 — 78,3%, 3 — 50%, 4 — 62,2%, 5 — 64,1%, 6 — 66,6%, 7 — 65,9%, 8 — 62,5%, 9 — 72,7%, 10 — 71,4%, 11 — 66,9%, 12 — 79,7%, 13 — 77,9%, 14 — 72,2%, 15 — 69,3%. Quarters treated with combinations of antibiotics with acetylosalicylic acid or chlormethine once were reinfected during the 3-month period half as often as those treated with other drugs.
2

Ocena skutecznosci ogolnego i miejscowego leczenia oedema uberis u krow

100%
Szalbierz M., Malinowski E., Branicki T.
Medycyna Weterynaryjna
|
1996
|
tom 52
|
nr 02
120-122
The studies have been performed on 105 experimental cows and 78 controls in a single dairy farm. Therapy was performed on cows by a single i.v. injection of 250 ml of Calcium borogluconatum and in the second group of cows 15 ml of Butapirazol. Other experimental cows were treated with an ointment applied twice within 24 hours. The ointment containing Butapirazol and dimethyl sulfoxide (DMSO) was administered in 20 cows and while in 22 cows the ointment with Butapirazol, acetylosalicylic acid (ASA) and DMSO. Examinations performed on days 3, 7 and 14 revealed that each therapeutic procedure accelerated the remission of oedema uberis by approximately 5 days compared with the controls. The best results was obtained by means of the ointment containing Butapirazol, ASA and DMSO. None of the therapy procedures resulted in changes in the blood serum and whey regarding haemotocrite values, Na, K, Ca and Mg concentrations or in any disturbances in health.
3

Wplyw Lydium-KLP na przebieg i skutecznosc dowymieniowej antybiotykoterapii klinicznych postaci mastitis u krow

100%
Malinowski E., Klossowska A., Szalbierz M., Kuzma R.
Medycyna Weterynaryjna
|
1997
|
tom 53
|
nr 01
45-48
The study was carried out on 217 cows affected with acute or chronic udder inflammations. The subsequent procedures were followed: 1 - Nafpenzal MC (three times every 24 hours) - a control group consisting of 44 cows; 2 - Lydium-KLP: 0.02 mg/kg of body weight once and antibiotics 3 times intramuscular every 24 hours in 20 cows; 3-a single injection of Lydium KLP (0.01 mg/kg b.w. intravenously) and Mastisan PN intramammary (58 - cows); 4-a single intramammary administration of Mastisan PN after 4-7 days from unsuccessful Lydium treatment; 5 - Mastisan PN used in 67 control cows (94 quarters). The following percentage of recoveries was observed: group 1-78 per cent of quarters of 79.5 per cent of cows; group 2 - 87.9 per cent of the quarters in 90 per cent of the cows; group 3 - 92.8 per cent of the quarters in 94.8 per cent of the cows; 4 - 89.7 per cent of the quarters in 92.9 per cent of the cows; 5 - 84.4 per cent of the quarters in 83.6 per cent of the cows. At day 5 after the antibiotic administration, a lack of clinical signs in milk (34.0 per cent) and in 30.8 per cent of the quarters was observed. 59.3 per cent of recoveries were recorded at that time after the combined treatment. The studies indicated that Lydium KLP at a dose of 0.01 mg/kg increased the efficacy of intramammary antibiotic treatment in cows.
4

Patogennosc dla gruczolu mlekowego drobnoustrojow wyosobnionych z podklinicznych i klinicznych przypadkow mastitis u krow

100%
Malinowski E., Klossowska A., Szalbierz M.
Medycyna Weterynaryjna
|
1992
|
tom 48
|
nr 10
467-469
Clinical udder and laboratory milk samples examinations were performed in 2084 cows from 20 farms. There was found clinical and subclinical mastitis in 1791 quarters of 945 cows. The clinical mastitis was caused by Str. agalactiae (36,2%), Staph. aureus (14,0%), Str. dysgalactiae (12,1%), Str. uberis (10,1%), E. coli (8,2%), Staph. epidermidis (8,2%), Micrococcus sp. (3,8%), yeasts (1,9%) and other bacteria (5,3%). Agents of subclinical mastitis were: Staph. epidermidis (32,5%), Micrococcus sp. (19,9%), Str. agalactiae (15,3%), Staph. aureus (11,9%), Str. uberis (10,3%), Str. dysgalactiae (8,1%) and other microorganisms (2,0%).
5
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Course of mastitis treatment in cows with Mastisan PN-MC

100%
Malinowski E., Klossowska A., Szalbierz M., Biegala T.
Bulletin of the Veterinary Institute in Puławy
|
1994
|
tom 38
|
nr 1
6

Zastosowanie Mastisanu PN w okresie zasuszania u krow

88%
Malinowski E., Biegala T., Markiewicz H., Szalbierz M., Kuzma R.
Medycyna Weterynaryjna
|
1994
|
tom 50
|
nr 04
168-170
Experiments were carried out on 137 cows. Before the drying period the udders were examined twice clinically, as well as their milk was tested bacteriologically and for its somatic cell level (CMT). Mastisan PN in the MC form (which is destined for mastitis treatment during lactation) was introduced into all quarters of the udders of 89 cows. Mastisan PN-DC containing a half dose of the Mastisan PN-MC was administered in 48 cows. Control examinations were performed twice, i.e. in the first and second week after calving. It was found that both drugs were highly effective (over 98 per cent). The prophylactic efficacy was 91 and 90.3 per cent respectively. Satisfactory therapeutic effects were observed in subclinical and clinical mastitis due to streptococci and staphylococci. The studies showed that Mastisan - a new drug elaborated at the National Veterinary Research Institute - was useful in the therapy of mastitis.
7

Wplyw iniekcji Lydium-KLP na wybrane wskazniki aktywnosci fagocytarnej leukocytow krwi cielat

88%
Kiczka W., Malinowski E., Kuzma K., Branicki T., Szalbierz M.
Życie Weterynaryjne
|
1994
|
tom 69
|
nr 04a
151-154
8

Terapia i profilaktyka mastitis za pomoca roznych lekow w okresie zasuszenia

88%
Malinowski E., Klossowska A., Markiewicz H., Szalbierz M., Biegala T.
Medycyna Weterynaryjna
|
1993
|
tom 49
|
nr 09
400-402
The investigations were carried out on 414 cows from one farm. The cows were evaluated twice before the end of lactation by clinical examination of udders and laboratory examination of milk samples. Antibiotic solutions (197 cows) or DC preparations (177 cows) were infused into all quarters after last milking. Groups of cows were treated with antibioties in combination with chlormethine or levamisol. It was found that after calving in control group (40 cows) there were more cows with infected quarters than before drying off. The results of treatment varied. Combinations of procainic penicillin (600 000 im) with streptomycine (0,5 g) gave better results than these antibiotics at 50% lower doses. Treatment with DC and Ilcocillin DC was more effective than the use of antibiotic solutions. Therapeutic and prophylactic effectiveness of antibiotics in dry cows increased after their supplementation with chlormethine.
9

Przebieg ustepowania mastitis subclinica po iniekcji Lydium-KLP

76%
Malinowski E., Klossowska A., Szalbierz M., Markiewicz H., Sobolewski J., Sobolewska S.
Życie Weterynaryjne
|
1996
|
tom 71
|
nr 09
304-306
10

Zastosowanie Lydium-KLP w leczeniu klinicznych postaci mastitis u krow

64%
Malinowski E., Kiczka W., Janicki C., Klossowska A., Dudko P., Nowak G., Markiewicz H., Szalbierz M., Biegala T.
Życie Weterynaryjne
|
1994
|
tom 69
|
nr 04a
179-182
11

Efektywnosc Lydium-KLP w leczeniu mastitis subclinica

64%
Malinowski E., Dudko P., Klossowska A., Markiewicz H., Szalbierz M., Branicki T., Kuzma R., Janicki C.
Medycyna Weterynaryjna
|
1995
|
tom 51
|
nr 03
156-159
The studies were done in 9 farms on 187 cows affected with a subclinical bacterial mastitis (260 quarters), sub- clinical aseptic mastitis (73 quarters) and latent infections (23 quarters). In the treatment, Lydium-KLP was applied intravenously once at a dose of 0.015-0.020 mg of lysozyme dimmer/kg of body weight. Control examinations carried out on 7, 14, 21 and 28 days after the treatment showed a high effectiveness of lysozyme dimmer in the treatment of subclinical mastitis. From 38.9% to 76.3% infected quarters (average 64.5 %) werer cured in particular farms. Effectiveness of the therapy used was high in cases when one quarter of an udder was affected and a somatic cell count did not exceed 3 million/ml of milk. The cure rate was the following: 50% for quarters infected with S. aureus, 57.9% for quarters infected with S. agalactiae and 88.1% for quarters infected with other microorganisms.
12

Skutecznosc Lydium-KLP w terapii podklinicznych postaci zapalenia gruczolu mlekowego krow

64%
Malinowski E., Kiczka W., Janicki C., Klossowska A., Markiewicz H., Szalbierz M., Biegala T., Nowak G., Nadolny M.
Życie Weterynaryjne
|
1994
|
tom 69
|
nr 04a
183-186
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