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The effect of different solvents on extraction with liquid carbon dioxide was studied. Extracted polynuclear aromatic hydrocarbons (PAHs) were applied on Sephadex C-50 gel. The model PAHs were phenanthrene, pyrene and benzo(a)pyrene. It is stated that the percentage of PAH model extractions was diminished when water-immiscible solvents (cyclohexane, chloroform and benzene) and methanol were added to the system. The addition of acetone and dimethylformamide caused increases in extraction percentage. The optimum content of both these solvents was shown to be approximately 0.8% in relation to the volume of C02 used .Under these conditions, a single extraction in the presence of acetone made it possible to recover 67% of phenanthrene, 62% of pyrene and 86% of benzo(a)pyrene, whereas in the presence of dimethylformamide these numbers were 66%, 80% and 9%, respectively.
Determination of polynuclear aromatic hydrocarbons (PAH-s) in sewage sludges is necessary before utilizing the sludges in agriculture, especially in industrial regions. Separation of PAHs has been the most difficult step of analysis. In this work, PAHs were separated by extraction. The best extraction solvents were chosen after reviewing literature. A new method of determining the partition coefficient has been proposed and applied to check if the chosen solvents were good enough for the present purposes. The results have shown that in the case of methanol and dimethylfor- mamide, extraction was nearly complete but the problems of finding a better solvent and mixing the solvents remained.
Background: Upper gastrointestinal bleeding is a common clinical problem and one of the main reasons for emergency hospitalization. It is associated with an overall mortality rate of 2% to 13%, despite advances in medical therapy. First-choice management is conservative treatment with endoscopic hemostasis. Aim of the study: The aim of the study was to examine the epidemiological and clinical characteristics of patients with upper gastrointestinal bleeding with a focus on the course of hospitalization based on the etiology Material and methods: A retrospective study was conducted in the Department of Surgery at the 4th Military Teaching Hospital in the years 2011–2016, comprising a total of 200 hospitalizations. 150 (75%) of the study group were men, and the mean age was 63.6±15.8 years. Results: Patients most frequently presented with melena (n=105; 53.1%) and hematemesis (n=79; 40%) or coffee ground vomiting (n=57; 28.7%). . 138 (69%) of hemorrhages were managed with endoscopic hemostasis, and in 43 (21.5%) of cases conservative treatment was adequate. In 12 (6%) of cases, laparotomy was the first-choice therapy and in 7 (3.5%) cases, surgery was performed after an attempt at endoscopic treatment had failed. The sources of bleeding were: gastric ulcer – 58 (29%), duodenal ulcer – 48 (24%), esophageal varices – 31 (15.5%), gastric tumor – 15 (7.5%), Mallory-Weiss syndrome – 10 (5%), and Dieulafoy’s lesion – 3 (1.5%). 16 (8%) of the hospitalizations were fatal. Conclusions: Upper gastrointestinal bleeding still has a high mortality rate (8%). It more frequently affects men and the elderly. Gastric and duodenal ulcers are the most common etiologies of bleeding. Esophageal varices and neoplasms are also a significant source of bleeding. Despite the progress in the pharmacological treatment of peptic ulcers, the complications resulting from gastrointestinal bleeding continue to be a serious clinical problem.
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