The benefits of physical activity are universal for all participants, including those with disabilities. The participation of individuals with disabilities in sports and recreational activities promotes inclusion, minimizes deconditioning, optimizes physical functioning, and enhances overall well-being. Despite these benefits, children with disabilities are more restricted in their participation, have lower levels of fitness, and have higher levels of obesity than their peers without disabilities. Professionals and parents may overestimate the risks or overlook the benefits of physical activity in children with disabilities. Well-informed decisions regarding each child’s participation must consider overall health status, individual activity preferences, safety precautions, and availability of appropriate programs and equipment. Child, family, financial, and societal barriers to participation need to be directly identified and addressed in the context of local, state, and federal laws. The goal is inclusion for all people with or without disabilities in appropriate sports and recreation activities. This study discusses the importance of physical activity, recreation, and sports participation for individuals with disabilities and offers suggestions to professionals and local government for regional development and the promotion of the quality of life for people with disabilities.