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1

Organizacja molekularna amfoterycyny B w modelowych ukladach o znaczeniu biologicznym

100%
Gagos M.
Rozprawy Naukowe. Akademia Rolnicza w Lublinie
|
2007
|
nr 320
1-103
2

Badania aktywności nowego preparatu zabezpieczającego pszczoły przed skutkami skażenia środowiska

63%
Arszulowicz A., Gagos M.
Pszczelarstwo
|
2014
|
nr 03
3

The effect of the dual fluorescence in selected 1,3,4 thiadazoles

51%
Matwijczuk A., Kaminski D., Niewiadomy A., Gagos M.
Current Topics in Biophysics. Supplement
|
2013
|
tom 36
|
nr 2A: Posters
4

The influence of Amphotericin B (AmB) on potassium channels from cell membrane of the fungus Candida albicans and human dermal fibroblasts (NHDF)

51%
Koselski M., Trebacz K., Chudzik B., Gagos M.
Current Topics in Biophysics. Supplement
|
2016
|
tom 39
|
nr A: Plenary lectures
5

Short-term pre-germination exposure to ELF magnetic field does not influence seedling growth in durum wheat (Triticum durum)

51%
Muszynski S., Gagos M., Pietruszewski S.
Polish Journal of Environmental Studies
|
2009
|
tom 18
|
nr 6
The effects of a short (15 and 30 s) exposure of durum wheat (Triticum durum) seeds to extremely low frequency magnetic field (f = 50 Hz, B = 15 mT) on germination and seedling growth under controlled laboratory conditions were studied. Germination rate, fresh weight of seedlings, seedlings height and chlorophyll contents were measured the 4th and 8th day after sowing. Magnetic field did not influence the seed germination process. Fresh weight was affected by applied treatments in the first four days (118% and 89% of control plans for 15 s and 30 s treatment, respectively). In the further period, the action of magnetic field (MF) pre-treatment on growth of seedlings was eliminated, resulting in compensation of growth potentialities. The chlorophyll levels in seedlings were significantly modified, on both the 4th (120% and 87% of control plans for 15 s and 30 s treatment, respectively) and 8th (94% for 15 s treatment and 96% for 30 s) days. However, the chlorophyll a and b ratios remained unchanged after MF treatments. The results show that MF may have, a mostly temporary, negative and positive effect on early growth, which is strongly dependent on the applied exposure time.
6

Metal-enhanced fluorescence of Amphotericin B

51%
Mackowski S., Krajnik B., Gagos M.
Current Topics in Biophysics. Supplement
|
2013
|
tom 36
|
nr 2A: Posters
7

The effect of amphotericin B on the cell membrane tightness and ion channel activity in protoplasts of Candida albicans

51%
Koselski M., Chudzik B., Gagos M.
Acta Neurobiologiae Experimentalis
|
2014
|
tom 74
|
nr 3
The patch clamp measurements carried out on the patch of the cell membrane showed that amphotericin B (AmB) applied at a low concentration (0.05 and 0.1 µM) causes a decrease in seal resistance, indicating loss of membrane tightness. Application of AmB also decreased the number of active outward rectifying potassium channels TOK1, but did not change the unitary conductance of the channels. Interestingly, AmB did not significantly change the open probability of the single channel. Such results indicate a lack of direct interaction of AmB and the channels. Membrane permeability changes after AmB were also observed by fluorescent microscopy. This research allowed us to conclude that integrity of the membrane between the pores formed by AmB is maintained. Supported by NCN grant DEC-2012/05/BNZ1/00037
8

Microscopic and spectroscopic analyses of selected agricultural formulations containing various nanostructures

51%
Kachel-Jakubowska M., Strubinska J., Matwijczuk A., Gagos M.
Polish Journal of Environmental Studies
|
2017
|
tom 26
|
nr 4
The aim of the present study was to analyse commercially available compounds containing nanoparticles in the form of Ag, Cu, and Ag sulphate colloids applied in agriculture. The compounds were analysed with TEM and FTIR spectroscopy, i.e., methods that can complement the commonly used research techniques such as EDX or Raman spectroscopy. The results of the microscopic examinations evidenced the presence of single spherical agglomerates (small granules) of the nanoparticle-containing products. Infrared spectroscopy revealed the presence of bands characteristic of vibrations that can be assigned to nanoparticle-X interactions, where X = S, C, or O in aqueous colloid solutions of the analysed samples. Additionally, bands characteristic for C-H stretching vibrations (probably associated with vibrations of the -CH₂ and -CH₃ groups) were observed as bands originating from compounds used as the carriers of the analysed systems. In the case of Ag sulphate, the most distinct band with a maximum at 2,863 cm⁻¹, which is characteristic of SH···Ag vibrations, can be observed, and its intensity may be associated with the nanostructure composition of the formulation, which is more diverse than that in the other two compounds.
9

Spectrophotometric analysis of the organisation of polyane antibiotic amphotericin B in lipid membranes

51%
Gagos M., Koper R., Gruszecki W. I.
Cellular and Molecular Biology Letters
|
2001
|
tom 06
|
nr 2A
395
10

Amphotericin B - An old drug, new ideas

51%
Czernel G., Chudzik B., Tracz I. B., Gagos M.
Current Topics in Biophysics. Supplement
|
2013
|
tom 36
|
nr 2A: Posters
11

Morphology and molecular organization of amphotericin B and its copper complex in model membrane system studied by brewster angle microscopy

51%
Arczewska M., Czernel G., Gagos M.
Current Topics in Biophysics. Supplement
|
2016
|
tom 39
|
nr A: Plenary lectures
12

Organization of antibiotic amphotericin B in model lipid membranes. A mini review

51%
Gruszecki W. I., Gagos M., Herec M., Kernen P.
Cellular and Molecular Biology Letters
|
2003
|
tom 08
|
nr 1
Amphotericin B (AmB) is a polyene antibiotic frequently applied in the treatment of fungal infections. According to the general understanding, the mode of action of AmB is directly related to the molecular organization of the drug in the lipid environment, in particular to the formation of pore-like molecular aggregates. Electronic absorption and fluorescence techniques were applied to investigate formation of molecular aggregates of AmB in the lipid environment of liposomes and monomolecular layers formed at the argon-water interface. It appears that AmB dimers, stabilized by van der Waals interactions, are present in the membrane environment along with the aggregates formed by a greater number of molecules. Linear dichroism measurements reveal that AmB is distributed between two fractions of molecules, differently oriented with respect to the bilayer. Molecules in one fraction remain parallel to the plane of the membrane and molecules in the other one are perpendicular. Scanning Force Microscopy imaging of the surface topography of the monolayers formed with AmB in the presence of lipids reveals formation of pore-like structures characterized by the external diameter close to 17 Å and the internal diameter close to 6 Å. All the findings are discussed in terms of importance of the molecular organization of AmB in the pharmacological action, as well as of the toxic side effects of the drug.
13

Organization of antibiotic amphotericin B in model lipid membranes

51%
Gruszecki W. I., Gagos M., Herec M., Kernen P.
Cellular and Molecular Biology Letters
|
2002
|
tom 07
|
nr Suppl.
14

The interaction of amphotericin B and zeaxanthin in lipid membranes: A spectroscopic study

51%
Gagos M., Herec M., Gruszecki W. I.
Cellular and Molecular Biology Letters
|
2002
|
tom 07
|
nr Suppl.
15

Application of fourier transform infrared spectroscopy in investigations of the neuroprotective potential of selected bioactive substances: Search for plasma and tissue neurodegeneration markers

45%
Schoenborn M., Janik E., Kluczyk D., Winiarczyk S., Gagos M.
Current Topics in Biophysics. Supplement
|
2016
|
tom 39
|
nr A: Plenary lectures
16

Spectroscopic studies of the quality of fatty acid methyl esters derived from waste cooking oil

45%
Matwijczuk A., Zajac G., Kowalski R., Kachel-Jakubowska M., Gagos M.
Polish Journal of Environmental Studies
|
2017
|
tom 26
|
nr 6
Biodiesel is a very attractive, biodegradable, renewable, and virtually nontoxic form of fuel. It is derived through base-catalysed transesterification of vegetable oils or animal fats. Analysis of biodiesel has become relevant, since the higher quality of the fuel is a key factor in commercialisation and market acceptance. The analytical methods employed are being constantly improved to meet this requirement. The most popular techniques for analysis of biodiesel include mainly chromatography and molecular spectroscopy. FTIR infrared spectroscopy is one of the most important spectroscopic techniques. The article presents the results of UV-Vis absorption spectroscopy and FTIR infrared spectroscopy analysis employed for investigating methyl esters of higher fatty acids obtained with laboratory methods from selected sunflower and rapeseed oils and waste animal fats provided by a slaughterhouse. Commercial methyl esters were included in the analyses for comparison. In all samples, the contents of free glycerol, methanol, esters, and linolenic acid methyl ester in FAME were determined mainly to facilitate the spectroscopic analysis. The results of the investigations conducted with the aforementioned methods clearly indicate that the analysed WCO esters can be successfully used as potential industrial-scale biofuels.
17

Microscopic image of honeybee drone spermatozoa in three diluents

45%
Borsuk G., Olszewski K., Strachecka A., Paleolog J., Gagos M.
Journal of Apicultural Science
|
2011
|
tom 55
|
nr 2
18
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Wplyw technologii zbioru na zawartosc chlorofili i karotenoidow w nasionach rzepaku, wytlokach i oleju

39%
Strobel W., Tys J., Sujak A., Gagos M., Zak W., Kotlarz A., Rybacki R.
Rośliny Oleiste - Oilseed Crops
|
2005
|
tom 26
|
nr 2
479-488
19

Pseudomonas aeruginosa alkaline protease exhibits a high renaturation capability

39%
Andrejko M., Sieminska-Kuczer A., Janczarek M., Janik E., Bednarczyk M., Gagos M., Cytrynska M.
Acta Biochimica Polonica
|
2019
|
tom 66
|
nr 1
20

Spectroscopic studies of the fluorescence effects of selected 1,3,4-thiadiazole in biologically important model systems

39%
Matwijczuk A., Kluczyk D., Karcz D., Gorecki A., Kamiński D., Niewiadomy A., Gagos M.
Current Topics in Biophysics. Supplement
|
2016
|
tom 39
|
nr A: Plenary lectures
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