PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2003 | 08 | 4 |
Tytuł artykułu

The interaction of daunorubicin and mitoxantrone with the red blood cells of acute myeloid leukemia patients

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The effect of DNR and MIT on erythrocyte membrane structure was examined using Electron Spin Resonance spectroscopy and the fluorimetric technique. The results suggest that the in vivo interaction of the drugs with the RBCs of AML patients led to a perturbation in the structure of plasma membrane components. Differences between DNR and MIT were only noted in the interaction of the drugs with deeper regions of the lipid bilayer.
Wydawca
-
Rocznik
Tom
08
Numer
4
Opis fizyczny
p.885-890,fig.
Twórcy
autor
  • University of Lodz, Banacha 12-16, 90-237 Lodz, Poland
autor
autor
autor
Bibliografia
  • 1. Fenstein, E., Canadni, E. and Weiner, L.M. Dependence of nucleic acid degradation on in situ free radical production by adriamycin. Biochemistry 32 (1998) 13156-13161.
  • 2. Wrzesien-Kus, A., Robak, T., Jamroziak, K., Wierzbowska, A., Dmoszynska, A., Adamczyk-Cioch, M., Kuliczkowski, M., Mazur, G., Holowiecki, J., Konopka, L., Maj, S., Marianska, B. and Zawilska, K. The treatment of acute myeloid leukemia with mitoxantrone, etoposide and low-dose cytarabine in elderly patients - a report of Polish Acute Leukemia Group (PALG) phase II study. Neoplasma 49 (2002) 405-411.
  • 3. Hande, K.R. Clinical application of anticancer drugs targeted to topoisomerase II. Biochim. Biophys. Acta 1400 (1998) 173-184.
  • 4. Burns, C.P., Haugstad, B.N. and Mossmann, C.J. Membrane lipid alteration: Effect on cellular uptake of mitoxantrone. Lipids 23 (1988) 393-397.
  • 5. Kołodziejczyk, P., Reszka, K. and Lown, J. Enzymatic oxidative activation on transformation of the antitumor agent mitoxantrone. Free Radie. Biol. Med. 5 (1988) 13-25.
  • 6. Dodge, J.T, Mitchell, C. and Hanahan, D.J. The preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes. Arch. Biochem. Biophys. 100 (1963) 119-130.
  • 7. Lowry, O.H., Rosenbrough, N.J, Farr, A.L. and Randal, R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193 (1951) 265- 275.
  • 8. Szwarocka, A., Robak, T., Krykowski, E. and Jóźwiak, Z. Interactions of anthracyclines with erythrocytes at hyperthermic temperature. Int. J. Pharmac. 135 (1996) 167-176.
  • 9. Van der Meer, B.W. Subcellular biochemistry. Fluorescence Studies on Biological Membranes (Hilderson HJ, Harris JR, ed.). Plenum Press. New York 13 (1988) 1.
  • 10. Garnier-Suillerot, A. and Gattegno, L. Interaction of adriamycin with human erythrocyte membranes. Role of the negatively charged phospholipids. Biochim. Biophys. Acta 936 (1988) 50-60.
  • 11. Arancia, G., Bordi, F., Calcabrini, A., Diociaiuti, M. and Molinari, A. Ultrastructural and spectroscopic methods in the study of anthracycline-membrane interaction. Pharmacol. Res. 32 (1995) 255-272.
  • 12. Szwarocka, A., Fiet, I. and Jóźwiak, Z. Idarubicin - induced changes in human erythrocyte membranes. Biomed. Letters 56 (1997) 81-89.
  • 13. Thomas, X. and Archimbaud, E. Mitoxantrone in the treatment of acute myelogenous leukemia: a review. Hematol. Cell Ther. 39 (1997) 163-174.
  • 14. Mollgard, L., Tidefelt, U., Surudman-Engberg, B., Lofgren, Ch., Lehman, S. and Paul, Ch. High single dose of mitoxantrone and cytarabine in acute non-lymphocytic leukemia. A pharmacokinetic and clinical study. Therapeut. Drugs Monit. 20 (1998) 640-645.
  • 15. Szwarocka, A., Fiet, I., Jóźwiak, Z., Krykowski, E. and Robak, T. Plasma membrane as a site of interaction of mitoxantrone in human erythrocytes. Hypertherm. Oncol. 2 (1996) 670-672.
  • 16. Davies, K.J.A. and Doroshow, J.H. Redox cycling of anthracyclines by cardiac mitochondria. Anthracycline radical formation by NADH dehydrogenase. J. Biol. Chem. 261 (1986) 3060-3067.
  • 17. Gallois, L., Fiallo, M. and Garnier-Suillerot, A. Comparison of the interaction of doxorubicin, daunorubicin, idarubicin and idarubicinol with large unilamellar vesicles. Circular dichroism study. Biochim. Biophys. Acta 1370 (1998) 31-40.
  • 18. Faulds, D., Balfour, J.A., Chrisp, P. and Langtry, H.D. Mitoxantrone: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the chemotherapy of cancer. Drugs 41 (1991) 400-449.
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.agro-article-cfd6c620-c95a-4371-b8e3-68b42ea12ca2
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.