Dystrybucja wazoaktywnego peptydu jelitowego i neuropeptydu Y w neuronach zwojow ledzwiowo-krzyzowych pnia wspolczulnego swini

• Autorzy: Skobowiat C , Gonkowski S. , Wojtkiewicz J. , Bossowska A. , Majewski M.

Warianty tytułu

EN

Distribution patterns of vasoactive intestinal peptide and NPY in the lumbar-sacral sympathetic chain ganglia of pigs

• Języki publikacji: PL

Abstrakty

EN

The aim of the study was to determine the existence and co-existence patterns of VIP and NPY in neurons and nerve fibers of porcine lumbar-sacral sympathetic chain ganglia. The studied ganglia were fixed with 4% buffered paraformaldehyde (perfusion) and then labeled by means of double-immunofluorescence using a mixture of antibodies cultivated in different species. The highest number of NPY-positive cells was observed in the lumbar ganglia and diminished in the direction of the caudal, where only single neurons were observed. In contrast, a different pattern of distribution was observed for VIP-positive neurons, whose number was higher in the more caudally located ganglia. Two populations of VIP-positive neurons could be distinguished: single, showing strong immunofluorescence and often with visible processes, located in the central part of the ganglia and a second population, composed of clusters of 4-8 cells and often co-localizing NPY. VIP-positive nerve fibers surrounded both NPY+ neurons and neurons lacking either NPY and/or VIP. The presence of a small number of NPY-positive neurons exhibiting very weak immunofluorescence in more caudally located SChG could suggest a "switch" of neuromediators produced there. An increase in the percentage of non-noradrenergic sympathetic neurons in more caudally located SChG may thus be implicative for a specific innervation pattern of target tissues of these ganglia.

Słowa kluczowe

PL

neuropeptyd Y; peptyd jelitowy wazoaktywny; neurony; trzoda chlewna; wspolwystepowanie; zwoje ledzwiowo-krzyzowe pnia wspolczulnego

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2006
• Tom: 62
• Numer: 12
• Opis fizyczny: s.1415-1419,fot.,bibliogr.

Twórcy

autor

Skobowiat C

• Uniwersytet Warminsko-Mazurski, ul.Oczapowskiego 13, 10-719 Olsztyn

autor

Gonkowski S.

autor

Wojtkiewicz J.

autor

Bossowska A.

autor

Majewski M.

Bibliografia

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