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2007 | 12 | 3 |

Tytuł artykułu

High level expression of STAG1-PMEPA1 in an androgen-independent prostate cancer PC3 subclone

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In this paper, we describe the isolation and characterization of two PC3 subclones. One subclone, mr, showed an epithelial phenotype, the other, M1, showed a sarcomatous morphology. Transplanted into nude mice, mr developed tumors at a dramatically faster rate than M1. Comparing the two subclones, differentially expressed genes were identified, including E-cadherin, IL-8 and STAG1/PMEPA1. These genes were expressed at higher levels in mr than in M1.








Opis fizyczny



  • Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan


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