High level expression of STAG1-PMEPA1 in an androgen-independent prostate cancer PC3 subclone

• Autorzy: Hirokawa Y S , Takagi A. , Uchida K. , Kozuka Y. , Yoneda M. , Watanabe M. , Shiraishi T.
• Języki publikacji: EN

Abstrakty

EN

In this paper, we describe the isolation and characterization of two PC3 subclones. One subclone, mr, showed an epithelial phenotype, the other, M1, showed a sarcomatous morphology. Transplanted into nude mice, mr developed tumors at a dramatically faster rate than M1. Comparing the two subclones, differentially expressed genes were identified, including E-cadherin, IL-8 and STAG1/PMEPA1. These genes were expressed at higher levels in mr than in M1.

Słowa kluczowe

EN

prostate specific antigen; interleukin 8; gene; solid tumour associated gene; gene expression; 5alpha-dihydrotestosterone; short tandem repeat; E-cadherin; PC3 subclone; prostate cancer cell line

• Wydawca: -
• Czasopismo: Cellular and Molecular Biology Letters
• Rocznik: 2007
• Tom: 12
• Numer: 3
• Opis fizyczny: p.370-377,fig.,ref.

Twórcy

autor

Hirokawa Y S

• Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan

autor

Takagi A.

autor

Uchida K.

autor

Kozuka Y.

autor

Yoneda M.

autor

Watanabe M.

autor

Shiraishi T.

Bibliografia

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