Preferencje help
Polish version English version Język
Widoczny [Schowaj] Abstrakt
Liczba wyników

Znaleziono wyników: 7

Liczba wyników na stronie
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników

Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych:  xylazine
help Sortuj według:

help Ogranicz wyniki do:
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
1

Effect of xylazine, medetomidine and dexmedetomidine on cardiac conduction in pigs

100%
Cepiel A., Noszczyk-Nowak A., Janiszewski A., Paslawski R., Paslawska U.
Medycyna Weterynaryjna
|
2018
|
tom 74
|
nr 03
The majority of anaesthetics used in studies regarding heart arrhythmias may affect the cardiac conduction system, thus influencing the results. In veterinary medicine, xylazine, medetomidine and dexmedetomidine are commonly used for premedication in laboratory and companion animals. To date, there have been no studies assessing the effect of these substances on the cardiac conduction system. The aim of this study was to assess the effect of xylazine, medetomidine and dexmedetomidine on the parameters of the cardiac conduction system in pigs. The study was carried out on 18 Great White Polish male pigs weighing from 21 to 40 kg. The animals were divided into three equal groups. The animals from the first group received xylazine at a dose of 2 mg/kg i.v.; those from the second group received medetomidine at 40 mcg/kg i.v.; and those from the third group received dexmedetomidine at 10 mcg/kg i.v. The electrophysiological activity of the heart was analysed using an invasive electrophysiological study (EPS). During the EPS, a decrease in the heart rate after substance administration was observed in all animals, but there were no statistically significant differences in the cardiac conduction parameters. A pro-arrhythmic effect of xylazine was observed, but no statistically significant changes in the EPS parameters were noted. Our results indicate that medetomidine and dexmedetomidine may be used as standard premedication drugs in electrophysiological studies in pigs. Their use may facilitate animal preparation procedures without affecting study results.
2

Effects of xylazine on thyroid hormones, insulin, and glucagon in dogs

72%
Gao L., Zhang Z., Zhang J., Wang H.
Bulletin of the Veterinary Institute in Puławy
|
2010
|
tom 54
|
nr 3
In this study, the effects of xylazine on serum levels of triiodothyronine (T3), tetraiodothyronine (T4), insulin (INS), and glucagon (GN) in dogs were investigated. The dogs before injection were used as control group (0 h). The dogs were injected with xylazine at 3 mg/kg, then blood was collected from the peripheral veins at 0.5, 2, 8, 24, 48, 72, and 120 h after the injection. Serum T3, T4, INS, and GN were measured by ELISA. The results revealed that the T3 level decreased in serum 0.5 h after the injection (P<0.05), while the change in T4 was not significant. The secretion of INS increased 8 h after the injection (P<0.05). The GN level increased 2 h and 8 h after the injection (P<0.05). However, all of these changes returned to the norm after 24 h.
3

Effects of xylazine on glutamate and GABA contents in the hippocampus and thalamencephal in the rat

72%
Yin B. S., Wang H. B., Gong D. Q., Li G. J., Gao L.
Bulletin of the Veterinary Institute in Puławy
|
2011
|
tom 55
|
nr 3
The purpose of the study was to define if anaesthetic action of xylazine could conceivably result from the potentiation of inhibitory neurotransmitters or the inhibition of excitatory neurotransmitter systems in the brain. Rats were injected with xylazine at a dose of 50 mg/kg b.w., and then the hippocampus and thalamencephal were removed at 0.1, 0.25, 0.5, 1, 1.5, 2, 4, and 6 h after the injection. Glutamate (Glu) and γ-aminobutyric-acid (GABA) were measured in the brain tissue by reversed-phase high-performance liquid chromatography. The results revealed that the hippocampus Glu level decreased significantly 0.1 h after the injection of xylazine, the thalamencephal GABA increased significantly 0.1 h after the injection, while the changes in hippocampus GABA and thalamencephal Glu were not significant. However, all of these changes returned to the normal level after 2 and 4 h, respectively. The results indicated the relative effects of xylazine on Glu and GABA levels in the hippocampus and thalamencephal.
4

Caudal extradural analgesia with lidocaine, xylazine, and a combination of lidocaine and xylazine in the Iranian river buffalo

72%
Saifzadeh S., Pourjafar M., Naghadeh B. D., Jalali F. S. S.
Bulletin of the Veterinary Institute in Puławy
|
2007
|
tom 51
|
nr 2
This study was conducted to compare the time of onset, duration of action, and the extent of analgesia produced by a lidocaine/xylazine combination with those produced by lidocaine and xylazine alone after injection into the caudal extradural space of the Iranian river buffalo. The study was designed as a prospective, descriptive, observer-blind trial, in a Latin square pattern. Eleven adult (aged over 2 years) non- gravid and healthy females of Iranian river buffaloes (Bubalus bubalis), weighing from 450 to 650 kg, were used. Caudal extradural analgesia was achieved on 3 occasions at 14 d intervals by injection of 2% lidocaine (L; 0.22 mg kg⁻¹), 2% xylazine (X; 0.05 mg kg⁻¹), and a combination of 2% lidocaine(0.22 mg kg⁻¹) / 2% xylazine (LX; 0.05 mg kg⁻¹) in a Latin square design. Analgesia was determined by the lack of response to pinprick and haemostat pressure in the skin of the caudal areas. X was significantly longer (5.5 ± 0.7 min) than that by L or LX. Duration of analgesia was significantly longer by LX (172.3 ± 17.7 min) than that by either drug used alone (lidocaine, 79.5 ± 5.7 min; xylazine, 136.4±11.4 min). In X and LX groups, the level of analgesia ascended to thoracic segments; however, in lidocaine-treated buffaloes thighs, flank, and udders remained sensitive. In all the buffaloes, xylazine, administered either alone or with lidocaine, induced mild to moderate ataxia. It was concluded that the LX combination provided a more rapid onset and a longer duration of analgesia, and a more cranial spread of analgesic effect compared with either drug alone. As a result, the LX combination may offer a fast and long lasting anaesthesia/analgesia to perform obstetrical and surgical procedures without the need for re-injection.
5

Immobilization (restraint) stress in Desert sheep and goats, and the influence of pretreatment with xylazine or sodium betaine thereon

58%
Al-Qarawi A. A.
Polish Journal of Veterinary Sciences
|
2005
|
tom 08
|
nr 1
6

Evaluation of the anesthetic effects of xylazine-ketamine, xylazine-tiletamine-zolazepam and tiletamine-zolazepam using clinical and laboratory parameters in rabbits

58%
Karasu A., Altug N., Aslan L., Bakir B., Yuksek N.
Medycyna Weterynaryjna
|
2018
|
tom 74
|
nr 10
The aim of this study was to evaluate the anesthetic effects of xylazine-ketamine (XK), xylazine-tiletaminezolazepam (XTZ) and tiletamine-zolazepam (TZ) using hematological and biochemical parameters in rabbits. A total of 18 rabbits were divided into three equal treatment groups (n = 6). The rabbits in the XK, XTZ, and TZ groups were administered xylazine (5 mg/kg) and ketamine (50 mg/kg), xylazine (5 mg/kg) and TZ (15 mg/kg), and TZ (15 mg/kg), respectively, via the intramuscular route. Following the injection, their reflexes were tested every 5 minutes. Heart rate, respiratory rate, and body temperature were determined before the injection (0 min) and at 5, 15, 30, 45, 60, 75, 90, and 120 min after injecting the anesthetic combinations. Furthermore, hematological and biochemical (alanine transaminase [ALT], aspartate transaminase [AST], alkaline phosphatase [ALP], bilirubin, blood urea nitrogen [BUN], and urea) analyses were also performed before, during, and after anesthesia administration. The duration of anesthesia and loss of reflexes were significantly longer in the XTZ group than in the other groups. However, in the TZ group, reflexes were remained. Respiratory rate and body temperature decreased in all the groups. Moreover, heart rate reduced only in the XK and XTZ groups, and the hematological parameters of all groups were comparable. Serum AST and ALP levels increased in the XTZ group compared to that in the XK and TZ groups, respectively. However, these increases were within the reference limits. The post-anesthesia serum BUN and urea levels significantly increased in the XTZ group (p < 0.05) compared to that in the other groups. Thus, although the XTZ combination provided satisfactory anesthetic effect in rabbits, it may be nephrotoxic. Therefore, its use for anesthesia induction in invasive renal procedures and experimental nephrotoxicity studies is not advisable.
7

Effect of xylazine-ketamine on arterial blood pressure, arterial blood pH, blood gases, rectal temperature, heart and respiratory rates in goats

58%
Afshar F. S., Baniadam A., Marashipour S. P.
Bulletin of the Veterinary Institute in Puławy
|
2005
|
tom 49
|
nr 4
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.