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The objective of this study was to investigate the impact of therapeutic laser irradiation on wound healing and skin regeneration in pigs as a supplementary treatment. The experiment was conducted on 32 young pigs divided into four groups: groups I and III served as control, group II comprised pigs with undamaged skin, and group IV consisted of pigs with cutaneous surgical wounds in the dorsal area. Groups II and IV were subjected to laser irradiation. Laser biostimulation was carried out using a CTL 1106 MX semiconductor laser in the continuous wave mode of operation at a wavelength of 810 nm and a maximum output of 100 mW. Following three weeks of observation and clinical skin trials, specimens for a histopathological analysis were collected. The reported results indicate that laser treatment shortens the wound healing process by speeding up the growth of granulation tissue and improving skin elasticity. Laser irradiation of the skin in pigs increases cellular infiltration of the corium and stimulates the proliferation of the stratum germinativum cells of the epidermis. Laser irradiation may be recommended as supplementary therapy in the treatment of surgical wounds.
Wound infection has become a major medical problem in recent years. This study was conducted to evaluate the healing activity of Capparis spinosa against surgical wounds infected by Escherichia coli. Twenty male rats were divided into two groups. Excisions were created surgically on the animals’ skin and then infected with E coli. Group 1 was treated with C spinosa while Group 2 was untreated. Wound biopsy specimens were collected on days 5, 10 and 16 and analyzed. Results showed that the hydroxyproline content in treatment group was significantly higher in various post wounding days. Protein content increased gradually in ten days. Results of histopathological studies showed moderate to intense granulation tissue formation in treated group on day 10. The histopathological studies showed, that the new epidermis in treated group was thicker than in control group on day 16 post wounding. The present study has demonstrated that ethanol extract of C spinosa includes properties that accelerate wound healing activities.
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