This article is a review of recently published papers dealing with the possible participation of environmental hormonally active compounds (natural and synthetic) in the ethiology of reproductive and other health disorders in animals and man. For some "old" synthetic chemicals (DDT, PCBs, dioxins, diethylstilbestrol, bisphenol A, atrazine and tributyltin) there is a link to the impact on wild animals. It has been hypothesized that in humans these compounds may be responsible for the increased incidence of breast and testicular cancer as well as for reproductive disorders. They generally occur at nontoxic concentrations, but exposure to their mixtures seems to be a major medical challenge. The food and drinking water are the main routes of exposure. During last decades much concern is focused on new groups of chemicals such as brominated flame retardants, phthalates, perfluorinated chemicals, parabens and veterinary drugs (anabolics).
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