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Immunotherapy in alveolar hydatidosis: an alternative to surgery

100%

Magambo J., Tanner C. E., Burt M. D. B.

Wiadomości Parazytologiczne

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1998

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tom 44

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nr 3

2

New generation adjuvants for subunit vaccines and their potential use in active immunotherapy

100%

Garcon N.

Bulletin of the Veterinary Institute in Puławy

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1998

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tom 42

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nr 1

3

Myeloid-derived suppressor cells in the tumor microenvironment: current knowledge and future perspectives

86%

Ibanez-Vea M., Zuazo M., Gato M., Arasanz H., Fernandez-Hinojal G., Escors D., Kochan G.

Archivum Immunologiae et Therapiae Experimentalis

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2018

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tom 66

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nr 2

4

Dendritic cell-based cancer immunotherapies

86%

Fujii S., Takayama T., Asakura M., Aki K., Fujimoto K., Shimizu K.

Archivum Immunologiae et Therapiae Experimentalis

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2009

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tom 57

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nr 3

189-198

5

High efficacy of methotrexate in patients with recurrent idiopathic acute anterior uveitis: a prospective study

86%

Bachta A., Kisiel B., Tlustochowicz M., Raczkiewicz A., Rekas M., Tlustochowicz W.

Archivum Immunologiae et Therapiae Experimentalis

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2017

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tom 65

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nr 1

6

Functional attributes of responding T cells in HCV infection: the recent advances in engineering functional antiviral T cells

86%

Pasetto A., Aleman S., Chen M.

Archivum Immunologiae et Therapiae Experimentalis

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2014

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tom 62

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nr 1

7

The PPAR alpha pathway in V gamma 9V delta 2 T cell anergy

86%

Poupot M., Boissard F., Betous D., Bardouillet L., Fruchon S., L Faqihi-olive F., Pont F., Mekaouche M., Ingoure S., Sicard H., Dubreuilh G., Fournie J.-J.

Cellular and Molecular Biology Letters

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2014

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tom 19

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nr 4

Phosphoantigens (PAgs) activate Vγ9Vδ2 T lymphocytes, inducing their potent and rapid response in vitro and in vivo. However, humans and nonhuman primates that receive repeated injections of PAgs progressively lose their Vγ9Vδ2 T cell response to them. To elucidate the molecular mechanisms of this in vivo desensitization, we analyzed the transcriptome of circulating Vγ9Vδ2 T cells from macaques injected with PAg. We showed that three PAg injections induced the activation of the PPARα pathway in Vγ9Vδ2 T cells. Thus, we analyzed the in vitro response of Vγ9Vδ2 T cells stimulated with a PPARα agonist. We demonstrated that in vitro PPARα pathway activation led to the inhibition of the BrHPP-induced activation and proliferation of human Vγ9Vδ2 T cells. Since the PPARα pathway is involved in the antigen-selective desensitization of human Vγ9Vδ2 T cells, the use of PPARα inhibitors could enhance cancer immunotherapy based on Vγ9Vδ2 T cells.

8

Enhancing cytotoxic T cell responses with altered-peptide ligands

86%

Zhao R., Collins E. J.

Archivum Immunologiae et Therapiae Experimentalis

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2001

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tom 49

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nr 4

9

Antigen-nonspecific activation of CD8plus T lymphocytes by cytokines: relevance to immunity, autoimmunity, and cancer

86%

Ramanathan S., Gagnon J., Ilangumaran S.

Archivum Immunologiae et Therapiae Experimentalis

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2008

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tom 56

|

nr 5

10

Regulatory T cells: magic bullets for immunotherapy?

86%

Frey O., Brauer R.

Archivum Immunologiae et Therapiae Experimentalis

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2006

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tom 54

|

nr 1

11

Effective tumor immunotherapy: start the engine, release the brakes, step on the gas pedal, ... and get ready to face autoimmunity

86%

Tirapu I., Mazzolini G., Rodriguez-Calvillo M., Arina A., Palencia B., Gabari I., Melero I.

Archivum Immunologiae et Therapiae Experimentalis

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2002

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tom 50

|

nr 1

12

Monoclonal and bispecific antibodies as novel therapeutics

86%

Booy E. P., Johar D., Maddika S., Pirzada H., Sahib M. M., Gehrke I., Loewen S., Louis S. F., Kadkhoda K., Mowat M., Los M.

Archivum Immunologiae et Therapiae Experimentalis

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2006

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tom 54

|

nr 2

13

Oncogene-targeted antisense oligodeoxynucleotides combined with chemotherapy or immunotherapy: A new approach for tumor treatment?

86%

Nieborowska-Skorska M., Nakashima M., Ratajczak M., Steplewski Z., Calabretta B., Skorski T.

Folia Histochemica et Cytobiologica

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1994

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tom 32

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nr 1

14

Cytokine-based immunotherapy of allergic disease

86%

Lewkowich I. P., HayGlass K. T.

Archivum Immunologiae et Therapiae Experimentalis

|

2001

|

tom 49

|

nr 4

15

Honey-bee venom allergy

86%

Adamek-Guzik T., Czerniawska-Mysik G., Guzik T.

Annals of Agricultural and Environmental Medicine

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1995

|

tom 02

|

nr 2

16

Cancer immunogene therapy

86%

Yoshizawa H., Kagamu H., Gejyo F.

Archivum Immunologiae et Therapiae Experimentalis

|

2001

|

tom 49

|

nr 5

17

Messenger RNA electroporation: an efficient tool in immunotherapy and stem cell research

86%

Van Driessche A., Ponsaerts P., Van Bockstaele D. R., Van Tendeloo V. F. I., Berneman Z. N.

Folia Histochemica et Cytobiologica

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2005

|

tom 43

|

nr 4

18

Immunotherapy in Gram-negative bacterial infections

86%

Lugowski C.

Acta Biochimica Polonica

|

1995

|

tom 42

|

nr 1

Endotoxins are responsible for initiation of septic shock which increases the number of fatalities in Gram-negative bacteremia among hospital patients. The morality from septic shock is still high despite recent developments in antibiotic therapy because antibiotics are unable to decrease the level of free lipopolysaccharide in the blood stream. Another approach to the treatment and prevention of septicaemia involves stimulation of an immune response against LPS. It was found that immunization with the core structures of endotoxin conjugated with proteins protected animals against infections and endotoxic shock. Anticonjugate sera are of great interest because they are directed against conserved parts of LPS and therefore could have cross-reactive and cross-protective properties with respect to many Gram-negative rods.

19

Specific immunotherapy stimulates the binding of histamine H2 receptor antagonist by lymphocytes

86%

Zak-Nejmark T., Malolepszy J., Nadobna G., Kuczynska-Sekieta K., Marczynska-Sarul E., Jutel M.

Archivum Immunologiae et Therapiae Experimentalis

|

1992

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tom 40

|

nr 2

20

CD40 stimulation induces differentiation of acute lymphoblastic leukemia cells into dendritic cells

86%

Luczynski W., Stasiak-Barmuta A., Ilendo E., Krawczuk-Rybak M., Malinowska I., Mitura-Lesiuk M., Parfienczyk A., Szymanski M.

Acta Biochimica Polonica

|

2006

|

tom 53

|

nr 2

Despite the very high percentage of long-term remissions in acute lymphoblastic leukemia (ALL) in children, some of them suffer from recurrence of the disease. New treatment modalities, e.g. effective geno- and immunotherapy are needed. The use of neoplasmatic cells to present tumor antigens is one of the approaches in cancer vaccines. ALL cells lack the expression of costimulatory molecules and are poor antigen presenting cells (APCs) for T-cell activation. CD40/40L interaction stimulates B-cells to proliferate, differentiate, upregulate costimulatory molecules and increase antigen presentation. The aim of the study was to test the hypothesis that ALL cells can be turned into professional APCs by CD40L activation. Children with B-cell precursor ALL were enrolled into the study. Mononuclear cells from bone marrow or peripheral blood were stimulated with CD40L and interleukin 4. Results: 1) after culture we noted upregulation of all assessed costimulatory, adhesion and activatory molecules i.e. CD1a, CD11c, CD40, CD54, CD80, CD83, CD86, CD123, HLA class I and II; 2) CD40L activated ALL cells induced proliferation of allogeneic T-cells (measured by [3H]thymidine incorporation). These results confirm the possibility of enhancing the immunogenicity of ALL cells with the CD40L system and indicate that this approach can be used in immunotherapeutic trials.

Ograniczanie wyników

Immunotherapy in alveolar hydatidosis: an alternative to surgery

New generation adjuvants for subunit vaccines and their potential use in active immunotherapy

Myeloid-derived suppressor cells in the tumor microenvironment: current knowledge and future perspectives

Dendritic cell-based cancer immunotherapies