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1

Indications to epigenetic dysfunction in the pathogenesis of common variable immunodeficiency

100%
Rae W.
Archivum Immunologiae et Therapiae Experimentalis
|
2017
|
tom 65
|
nr 2
2
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Respiratory failure associated with ascariasis in a patient with immunodeficiency: a case report

100%
Lanocha A., Zdziarska B., Lanocha-Arendarczyk N., Kosik-Bogacka D., Guzicka-Kazimierczak R., Marzec-Lewenstein E.
Annals of Parasitology
|
2016
|
tom 62
|
nr Suppl.
3

Viral vaccines: selected topics

100%
Kantoch M.
Archivum Immunologiae et Therapiae Experimentalis
|
1996
|
tom 44
|
nr 5-6
4

High molecular mass dextran sulfate increases expression of HIV-1 coreceptor CCR-5 in macrophage-monocytes in culture

100%
Jagodzinski P. P., Trzeciak W. H.
Acta Biochimica Polonica
|
1998
|
tom 45
|
nr 1
It has been reported that high molecular mass dextran sulfate (HMDS) enhances the infection of monocyte-macrophages by HIV-1. We observed that in monocyte-macrophages maintained in the presence of HMDS the expression of HIV-1 coreceptor CCR-5 was increased approximately 5-fold at the transcriptional level. We postulate that the increased expression of CCR-5 might be responsible for HMDS-enhanced infectivity of monocyte-macrophages by HIV-1.
5

Allogeneic bone marrow transplantation corrects the immunodeficiency in PNP deficiency but does not reverse the neurological abnormalities

100%
Hallett R. J., Gaspar B., Duley J. A., Fairbanks L. D., Simmonds H. A.
Cellular and Molecular Biology Letters
|
1999
|
tom 04
|
nr 3
6

Anaphylaxis to IVIG

84%
Williams S. J., Gupta S.
Archivum Immunologiae et Therapiae Experimentalis
|
2017
|
tom 65
|
nr 1
7

How influenza's neuraminidase promotes virulence and creates localized lung mucosa immunodeficiency

84%
Bhatia A., Kast R. E.
Cellular and Molecular Biology Letters
|
2007
|
tom 12
|
nr 1
Neuraminidase (NA) is an enzyme coded for by the genome of influenza critical for its pathogenicity and survival. Three currently accepted roles for this NA in promoting influenza virulence are: 1. NA cleaves newly formed virus particles from the host cell membrane. Without NA, newly formed virus would remain attached to the cell within which it was produced. 2. NA prevents newly released virus particles from aggregating to each other, preventing clumping that would reduce dissemination. 3. NA promotes viral penetration of sialic acid-rich mucin that bathes and protects respiratory epithelium through which the virus must spread and replicate. We outline here previous research evidence of two further, albeit hypothetical, functions of NA that together could cause disruption the mucosa-IgA axis, creating localized partial immunosuppressed state, enhancing both influenza infection itself and secondary bacterial pneumonia: 4. IgA provides primary immunoglobulin defense of mucosal surfaces. The hinge region of IgA is normally sialylated. IgA denuded of sialic acid is recognized, bound, and cleared by hepatic asialoglycoprotein receptor (ASGPR). Thus, IgA exposed to free NA would be so denuded and have increased hepatic clearance. 5. NA removes sialic acid moieties from mucosa-residing gamma/delta T cells or IgA producing B cells. Previous work indicates desialylation of these lymphocytes' outer cell membrane results in altered homing, to bone marrow, away from mucosa. Currently marketed NA inhibitors oseltamivir (Tamiflu) and zanamivir (Relenza) are FDA approved in USA for influenza prophylaxis and treatment. These NA inhibitors lower incidence of secondary bacterial infection in cases where an influenza infection occurs despite their use. Moreover, they are ameliorative in patients with secondary bacterial infections treated with antibiotics, a benefit that surpasses the treatment of antibiotics alone. We interpret these last two points as indicating our ascription of localized immunosuppression to influenza's NA could be correct and lead to new treatments of infections generally.
8

Immunological system status and the appearance of respiratory system disturbances in thymectomized patients

84%
Krawczyk P., Adamczyk-Korbel M., Kieszko R., Korobowicz E., Milanowski J.
Archivum Immunologiae et Therapiae Experimentalis
|
2007
|
tom 55
|
nr 1
9
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Basis for novel human immunodeficiency viruses vaccines: antigenetically expanded HIV PR55 gag based viruslike particles

84%
Wagner R., Deml L., Notka F., Yiming S., Wolf H.
Bulletin of the Veterinary Institute in Puławy
|
1998
|
tom 42
|
nr 1
10

Toll-like receptors’ pathway disturbances are associated with increased susceptibility to infections in humans

67%
Frazao J. B., Errante P. R., Condino-Neto A.
Archivum Immunologiae et Therapiae Experimentalis
|
2013
|
tom 61
|
nr 6
11
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Difficulties associated with the diagnosis of mycosis of the oral cavity and throat in chronic lymphocytic leukemia (CLL)

67%
Kaczmarczyk D., Morawiec-Sztandera A., Niedzwiecka I., Kurnatowski P.
Wiadomości Parazytologiczne
|
2011
|
tom 57
|
nr 3
12

Presentation of antigen by B cell subsets. IV. Defective T-B cell signalling causes inability to present antigen by B cells from immunodeficient mice

67%
Zimecki M., Kapp J. A.
Archivum Immunologiae et Therapiae Experimentalis
|
1994
|
tom 42
|
nr 5-6
13

Cellular immune activation, neopterin production, tryptophan degradation and the development of immunodeficiency

67%
Widner B., Wirleitner B., Baier-Bitterlich G., Weiss G., Fuchs D.
Archivum Immunologiae et Therapiae Experimentalis
|
2000
|
tom 48
|
nr 4
14

Tumor escape from immune surveillance

67%
Costello R. T., Gastaut J. A., Olive D.
Archivum Immunologiae et Therapiae Experimentalis
|
1999
|
tom 47
|
nr 2
15

Immunosupresja - nieinfekcyjne przyczyny niskiej efektywności w produkcji świń

51%
Porowski M., Porowski M., Porowski S., Porowski M.
Lecznica Dużych Zwierząt. Ogólnopolski Kwartalnik dla Lekarzy Weterynarii
|
2018
|
tom 13
|
nr 4
16

Mannheimia haemolytica od bakterii komensalicznej do zabójcy bydła

51%
Bayron C.
Lecznica Dużych Zwierząt. Ogólnopolski Kwartalnik dla Lekarzy Weterynarii
|
2018
|
tom 13
|
nr 1
17

Familial study of ataxia telangiectasia. Heterozygote identification on the basis of sensitivity of gamma-irradiated cultures to caffein post-treatment

51%
Pawlak A. L., Kotecki M., Ignatowicz R.
Bulletin of the Polish Academy of Sciences. Biological Sciences
|
1994
|
tom 42
|
nr 3
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