Wyniki wyszukiwania - AGRO

1

The unusual structure and unknown function of selenoprotein P

100%

Zachara B. A.

Applied Biology Communications. Lublin Scientific Center

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1992

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tom 02

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nr 2

2

Serum total antioxidant capacity and enzymatic defence of dogs with chronic heart failure and atrial fibrillation: a preliminary study

86%

Michalek M., Tabis A., Noszczyk-Nowak A.

Journal of Veterinary Research

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2020

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tom 64

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nr 3

3

Estimation of antioxidative enzymes of the rats' livers remaining on a diet enriched with nitrates [V] and vitamin E

86%

Kusz E., Wardas M., Stec M., Radwanska-Wala B., Manowski A.

Polish Journal of Food and Nutrition Sciences

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2001

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tom 10

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nr 1

The activity of superoxide dismutase (SOD) and glutathione peroxidase was marked in homogenates of rat's (type Wistar) liver after 1, 2 and 3 months of watering them with 0.02% and 0.04% solution of sodium nitrate in the situation when the rats' diet was supplemented with vitamin E. In comparison with the control group it was stated that the activity of SOD increases and the activity of GPx decreases in liver homogenates sampled from rats watered with nitrate solutions. In liver homogenates sampled from rats which apart from being watered with nitrates were also administered vitamin E, a relative normalisation of the activity of both enzymes was stated. The obtained results indicate direct or indirect free- radical character of the nitrates effect.

4

Damage to erythrocytes caused by 2,3,7,8-tetrachlorodibenzo-p-dioxin [in vitro]

86%

Bukowska B.

Cellular and Molecular Biology Letters

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2004

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tom 09

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nr 2

The effects of the exposure of human erythrocytes to different concentrations of 2,3,7,8-tetrachlorodibenzo-p-dioxin were studied. Particular attention was paid to lipid peroxidation, haemoglobin oxidation, and changes in the activity of catalase and glutathione peroxidase. Human erythrocytes at a 5% haematocrit were incubated with 2,3,7,8-TCDD at concentrations of 0.2 ppm to 1.6 ppm (ng-mg/ml erythrocytes) for 1 hour. The results obtained show that 2,3,7,8-TCDD induces the generation of lipid peroxides and the oxidation of Hb, and decreases the activity of catalase and glutathione peroxidase. This supports the thesis that TCDD causes oxidative stress in erythrocytes.

5

Effect of potential probiotic activity of Enterococcus faecium EE3 strain against Salmonella infection in Japanese quails

86%

Marcinakova M., Strompfova V., Boldizarova K., Laukova A., Gancarcikova S.

Bulletin of the Veterinary Institute in Puławy

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2004

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tom 48

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nr 4

6

Activities of glutathione peroxidase and catalase in organs from vanadium-treated rats

72%

Krosniak M., Krzysciak W., Kareta A., Grybos R.

Acta Biologica Cracoviensia. Series Zoologia

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2009

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tom 51

39-48

7

Time course evaluation of lacosamide alone and in polypharmacy on behavioral manifestations and oxidative stress in lithium-pilocarpine-induced model

72%

Shakeel W., Javaid S., Anjum S. M. M., Rasool M. F., Samad N., Alasmari F., Alasmari A. F., Alaqil F. A., Alqarni S. A., Alotaibi F. M., Alqahtani F., Imran I.

Journal of Physiology and Pharmacology

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2020

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tom 71

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nr 4

8

In vitro effects of quercetin on oxidative stress mediated in human erythrocytes by benzoic acid and citric acid

72%

Bas H., Kalender S., Pandir D.

Folia Biologica

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2014

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tom 62

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nr 1

9

Mimicking of glutathione peroxidase deficiency by exposition of JAR cells to increased level of synthetic hydroperoxide

72%

Hallmann A., Milczarek R., Szkatula M., Wozniak M., Spodnik J. H., Klimek J.

Folia Morphologica

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2005

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tom 64

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nr 4

304-308

A short chain synthetic analogue of lipid hydroperoxides was used to overload glutathione peroxidase (GPx) in human choriocarcinoma cell line JAR cells. Cells exposed to 100 µM tBuOOH displayed a 40% reduction in ATP level and significantly increased in membrane permeability, visualised by the lactate dehydrogenase (LDH) release into the extracellular medium. The intracellular level of oxygen free radicals measured as an oxidation of the dichlorodihydro-fluorescein diacetate (H₂DCF-DA) significantly increased after 2 hours of cell exposition to 100 µM tBuOOH. Concomitantly MDA, 4-HNE level increased to 2 nmol/mg of cell protein after 2 hours. Mitochondria stained with MitoTracker Red CMXRos displayed a filamentous appearance in control cells but changed into granular less energised organelles after exposition to tBuOOH. Collectively, the above results indicate the importance of the contribution of oxidative stress in the development of pre-eclampsia.

10

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Utilization of selenium compounds in nutrition of lambs

72%

Slupczynska M., Kinal S., Hadrys M., Krol B.

Journal of Elementology

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2009

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tom 14

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nr 1

157-163

The level of mineral utilization depends on many factors related to animals as well as to the chemical form of given nutrients. It has been experimentally demonstrated that animals utilize inorganic forms of minerals less efficiently than organic ones. Hence, an attempt has been made to evaluate the bioavailability of selenium bound in different compounds to lambs. Selenium supplementation in fodder mixtures was another aspect included in our tests. Thus, an experiment was conducted on 48 growing lambs, testing the level and chemical forms of selenium in fodder mixtures for animals. In group I (the control) lambs received fodder mixture without any selenium supplement. In the experimental groups, selenium was supplemented as sodium selenite in the amount 0.2 mg Se kg-1 d.m. feeds (II), or selenium enriched yeast (Se-yeast) in the amounts of 0.1 and 0.2 mg Se kg-1 d.m. of feed groups III and IV, respectively. At the end of the experiment, when animals had reached 35 kilos of weight, blood samples were taken. The activity of glutathione peroxidase was estimated in heparinized blood samples. Eight lambs were chosen from each group and killed to collect samples of soft tissues (liver, kidney, brain, muscle). The content of selenium was determined in the tissue samples. Supplementation of feeds for lambs with selenium, both inorganic (sodium selenite) and organic (Se-yeast), increased the content of the element in soft tissues of animals. The highest level of the element was found in the liver and kidneys: 4.65 and 4.90 and 2.10 and 2.30 mg kg-1 fresh tissue, of the lambs receiving sodium selenine and Se-yeast in the amount 0.2 mg Se kg-1 D.M. of feed (groups II and IV), respectively. Selenium compounds added to feeds given to lambs significantly (P£0.01) increased activity of GSH-Px in blood, especially in the case of animals which received yeast enriched with selenium. In blood of the lambs which received feeds with Se-yeast in the amount 0.2 mg Se kg-1 d.m. of feed (group IV), the activity of glutathione peroxidase was by 129.71 U gHb-1 higher, and of the animals which received Se-yeast in the amount 0.1 mg kg-1 d.m. or sodium selenite, the activity of the enzyme was higher by 86.33 and 86.35 U gHb-1, respectively, than the activity of this enzyme in blood of animals from the control group. Supplementation of lambs’ rations with Se in the form of selenite or yeast enriched with selenium forms increased the content of Se in soft tissues and gluthatione peroxidase activity in comparison with animals which did not receive additional doses of this nutrient in fodder mixtures. The availability of Se was more profoundly affected by the amount of the element added rather than its form.

11

Alterations in glutathione peroxidase and superoxide dismutase activities in plasma and saliva in relation to disease activity in patients with Crohn's disease

72%

Szczeklik K., Krzysciak W., Domagala-Rodacka R., Mach P., Darczuk D., Cibor D., Pytko-Polonczyk J., Rodacki T., Owczarek D.

Journal of Physiology and Pharmacology

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2016

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tom 67

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nr 5

12

Selenium supplementation to chronic kidney disease patients on hemodialysis does not induce the synthesis of plasma glutathione peroxidase

72%

Zachara B. A., Gromadzinska J., Zbrog Z., Swiech R., Wasowicz W., Twardowska E., Jablonska E., Sobala W.

Acta Biochimica Polonica

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2009

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tom 56

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nr 1

183-187

Background: Numerous authors have shown that selenium (Se) concentration and glutathione peroxidase (GSH-Px) activity in plasma of chronic kidney disease (CKD) patients are lower than in healthy subjects, but there are only few publications on the level of GSH-Px protein in those patients and no reports on the effect of Se supplementation to HD patients on the level of this enzyme. Subjects and Methods: Se concentration and GSH-Px protein level in plasma were measured in a group of 30 CKD patients on hemodialysis (HD) supplemented with 200 μg Se/day for 3 months, and 28 patients on HD administered with placebo. Se concentration was measured by graphite furnace atomic absorption spectrometry and plasma GSH-Px protein level by the sandwich ELISA method using polyclonal antibody specific for human plasma GSH-Px. Results: Se concentration in patients on placebo did not change throughout the 3-month study period, but increased significantly in Se supplemented group. Se supplementation to CKD patients on HD had no effect on the level of GSH-Px protein. Conclusions: The lack of GSH-Px protein in CKD patients on HD is not linked to Se deficiency since the level of this element increased after Se supplementation while enzyme protein level did not change. The damaged kidney of HD patients is unable to synthesize GSH-Px, even after induction with selenium.

13

The protective effects of zinc in experimental gentamicin induced acute renal failure in rats

72%

Teslariu O., Pasca A. S., Mititelu-Tartau L., Schiriac C. E., Gales C., Saftencu P. M., Nechifor M.

Journal of Physiology and Pharmacology

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2016

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tom 67

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nr 5

14

Evaluation of oxidative stress parameters in dogs with brachycephalic obstructive airway syndrome before and after surgery

72%

Erjavec V., Vovk T., Nemec Svete A.

Journal of Veterinary Research

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2021

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tom 65

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nr 2

15

Molecular characterization and functional analysis of a glutathione peroxidase gene from Aphelenchoides besseyi (Nematoda: Aphelenchoididae)

72%

Wang B.-Y., Wen R.-R., Ma L.

Acta Parasitologica

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2017

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tom 62

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nr 3

16

Influence of selenium compounds on glutathione peroxidase [GSH-Px] level in lamb blood

72%

Hadrys M., Kinal S., Antonowicz-Juchniewicz J., Jedrychowska I.

Electronic Journal of Polish Agricultural Universities. Series Veterinary Medicine

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2007

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tom 10

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nr 1

17

The effects of soybean selenium proteinate on tissue selenium and meat quality traits in finishing pigs

72%

Svoboda M., Fajt Z., Banoch T., Salakova A., Drabek J.

Polish Journal of Veterinary Sciences

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2011

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tom 14

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nr 1

The purpose of the present study was to evaluate the effects of soybean selenium proteinate on Se tissue retention and meat quality in pigs. In group A (n=11) the mixtures were supplemented with soybean selenium proteinate, in group B (n=11) with sodium selenite and in group C (n=11) with Se-enriched yeast (0.3 mg Se per kg in all groups). The use of soybean selenium proteinate resulted in lower retention of Se in tissues (liver, heart, muscle) compared to Se-enriched yeast. Selenium concentrations in tissues achieved by soybean selenium proteinate and sodium selenite were comparable. No differences in serum Se, serum GSH-Px and meat quality traits were found among the groups.

18

Glutathione-dependent responses of plants to drought: a review

72%

Labudda M., Azam F. M. S.

Acta Societatis Botanicorum Poloniae

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2014

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tom 83

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nr 1

Water is a renewable resource. However, with the human population growth, economic development and improved living standards, the world’s supply of fresh water is steadily decreasing and consequently water resources for agricultural production are limited and diminishing. Water deficiency is a significant problem in agriculture and increasing efforts are currently being made to understand plant tolerance mechanisms and to develop new tools (especially molecular) that could underpin plant breeding and cultivation. However, the biochemical and molecular mechanisms of plant water deficit tolerance are not fully understood, and the data available is incomplete. Here, we review the significance of glutathione and its related enzymes in plant responses to drought. Firstly, the roles of reduced glutathione and reduced/ oxidized glutathione ratio, are discussed, followed by an extensive discussion of glutathione related enzymes, which play an important role in plant responses to drought. Special attention is given to the S-glutathionylation of proteins, which is involved in cell metabolism regulation and redox signaling in photosynthetic organisms subjected to abiotic stress. The review concludes with a brief overview of future perspectives for the involvement of glutathione and related enzymes in drought stress responses.

19

Characterization and analyses of hydrophobic clusters, acetylation and myristoylation sites in plant glutathione peroxidase sequences

72%

Ganguli S., Polley A., Datta A.

International Letters of Natural Sciences

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2015

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tom 01

Incomplete reduction of oxygen molecules is the primary source for the formation of reactive oxygen species (ROS) during cytosolic metabolism or mitochondrial respiration. These phenomenons may be as a result of biotic or abiotic stress. Exposure to exogenous stimuli such as radiation might be an alternative pathway of ROS production. Thus plants require counter defense strategies to combat the increase of this toxic molecular build up in its cell cytoplasm. As a result they have devised an army of free radical scavenging enzymes which enable them to dissipate the oxidative stress imposed by the accumulation of these toxic moieties. Glutathione Peroxidase forms an important part of this arms race along with several catalases and organelle specific enzymes such as superoxide dismutase. Plant glutathione peroxidases(GPXs) have been studied exclusively for their evolutionary lineages since they represent a hybrid class of molecules in context of the presence and absence of selenocysteine at their catalytic centres, the former situation predominant in non vascular plant groups while the later a predominant feature of vascular plants. This analysis focuses on three important aspects of protein structure analyses – hydrophobic cluster analyses for identification of homologues, and acetylation and myristoylation sites which provide us with information regarding the post translational modifications of a particular protein group. Specific patterns of clusters along with acetylation and myristoylation site frequencies were obtained which indicate that GPXs of non vascular plant members possess less chances of getting myristoylated while acetylation was predominant in most land plant lineages but absent in aquatic members.

20

Isolation and computational characterization of glutathione peroxidase gene from an aquatic fern - Salvinia molesta

72%

Rahaman S., Singh P. K., Basu P., Gupta S., Basu M., Ganguli S.

International Letters of Natural Sciences

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2016

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tom 51

Pteridophytes and more specifically ferns represent a large but threatened group of plants which often serve as important environmental markers for pollution. Reports regarding stress responses in ferns are rare, apart from a few studies involving the ecological distribution and molecular marker studies. This work isolates a glutathione peroxidase enzyme from an aquatic fern widely distributed in fresh and polluted water bodies adjacent to sources of environmental polluted sources. Further computational analyses were performed to study the structure of the protein encoded by the open reading frame. Results indicate the presence of a large number of binding pockets which serve as important binding sites in the interactions with the cognate ligands.

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