Wyniki wyszukiwania - AGRO

1

Adaptation of a colorimetric procedure with diphenylcarbazide for determination of free fatty acids in chloroplasts

100%

Saczynska V., Miskiewicz E., Kaniuga Z.

Acta Physiologiae Plantarum

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1994

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tom 16

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nr 2

2

The effect of cadmium on the utilization of free fatty acids in the skeletal muscles in rats

88%

Falkus B., Kielan Z., Ziolkowska B., Jethon Z.

Acta Biologica Silesiana

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1990

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tom 15

3

Mitochondrial function of human preadipocytes may be modulated by antioxidants quercetin and beta carotene, and exogenous free fatty acids

75%

Sliwa A., Goralska J., Awsiuk M., Czech U., Gruca A., Kiec-Wilk B., Knapp A., Dembinska-Kiec A.

Polish Journal of Food and Nutrition Sciences

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2011

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tom 61

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nr Suppl.1

4

Effect of adrenalin, insulin and contractions on the content of the free fatty acid fraction in skeletal muscle

75%

Chabowski A., Baranczuk E., Gorski J.

Journal of Physiology and Pharmacology

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2005

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tom 56

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nr 3

The fraction of free fatty acids (FFA) is present in skeletal muscles. However, there is almost no data regarding regulation in the content of this intramuscular lipid pool. We took advantage of the isolated muscle preparation to examine whether: a) increasing exogenous concentration of FFA (500µM or 700µM, 30min) b) insulin (10.00 I.U./L, 30min), c) adrenalin (4.4 nM, 30min), or d) contractions (200ms, tetani, 1Hz, 30min), affect the FFA content inside myocytes. Incubation of soleus (S) and extensor digitorum longus (EDL) with increasing concentrations of exogenous FFA (from 500µM to 700µM) resulted in an increase in the total FFA fraction in both muscles studied (by 280.2% and 259.1%, respectively). In contracting muscles FFA pool was significantly reduced both in S (by 73.1%) and in EDL (by 31.1%). Neither stimulation by adrenalin nor insulin affected the total content of FFA fraction in the muscles examined. We conclude that a) increased availability of exogenous FFA at the sarcolemma level results in an increase in the size of intramuscular FFA fraction b) the intracellular FFA fraction is utilized by contracting muscles with regard to the fiber composition and to a greater extent in more oxidative muscles, c) FFA fraction remains stable upon stimulation by insulin or adrenalin.

5

Coenzyme Q releases the inhibitory effect of free fatty acids on mitochondrial glycerophosphate dehydrogenase

75%

Rauchova H., Drahota Z., Rauch P., Fato R., Lenaz G.

Acta Biochimica Polonica

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2003

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tom 50

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nr 2

Data presented in this paper show that the size of the endogenous coenzyme Q (CoQ) pool is not a limiting factor in the activation of mitochondrial glyceropho- sphate-dependent respiration by exogenous CoQ3, since successive additions of succinate and NADH to brown adipose tissue mitochondria further increase the rate of oxygen uptake. Because the inhibition of glycerophosphate-dependent respiration by oleate was eliminated by added CoQ3, our data indicate that the activating effect of CoQ3 is related to the release of the inhibitory effect of endogenous free fatty acids (FFA). Both the inhibitory effect of FFA and the activating effect of CoQ3 could be demonstrated only for glycerophosphate-dependent respiration, while succinate- or NADH-dependent respiration was not affected. The presented data suggest differences between mitochondrial glycerophosphate dehydrogenase and succinate or NADH dehydrogenases in the transfer of reducing equivalents to the CoQ pool.

6

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Dizel'noe biotoplivo s zhirosoderzhashhikh otkhodov pticevodstva

63%

Mushtryk M., Sukhenko J.

Motrol. Motoryzacja i Energetyka Rolnictwa

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2014

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tom 16

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nr 3

7

Effect of selected antioxidants on some fat characteristics and sensory quality of raw sausages

63%

Pyrcz J., Kowalski R., Bilska A., Uchman W.

Electronic Journal of Polish Agricultural Universities. Series Food Science and Technology

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2008

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tom 11

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nr 2

8

The significance of plasma triacylglycerols in metabolism of free fatty acids and triacylglycerols in rat skeletal muscles

63%

Krawczuk I., Gorski J.

Acta Physiologica Polonica

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1990

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tom 41

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nr 7

Krawczuk I. and Górski J.: The significance of plasma triacylglycerols in metabolism of free fatty acids and triacylgrylcerols in rat skeletal muscles. Acta Physiol. Pol., The continuous uptake of plasma triacyl- gylcerols has been shown to be necessary to maintain the stable resting concentration of free fatty acids and triacylglycerols only in a muscle composed of fast - twitch oxidative gylcolytic fibres.

9

Eicosapentaenoic acid as mitochondria protective agent in endothelial cells exposed to stress

63%

Goralska J., Sliwa A., Zapala B., Gruca A., Czech U., Awsiuk M., Dembinska-Kiec A.

Polish Journal of Food and Nutrition Sciences

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2011

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tom 61

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nr Suppl.1

10

Effect of exercise on energy substrates metabolism in tissues of adrenalectomized rats

63%

Gorski J., Nowacka M., Namiot Z., Kiryluk T.

Acta Physiologica Polonica

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1987

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tom 38

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nr 4

11

Free fatty acid receptors and their physiological roles in the colon

63%

Karaki S. I., Kuwahara A.

Medycyna Weterynaryjna

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2010

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tom 66

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nr 03

147-154

Free fatty acids (FFAs) are not only an important source of energy but they also play key roles in regulating various physiological responses. FFAs including short-chain fatty acids (SCFAs) have recently been demonstrated to act as ligands of several G-protein-coupled receptors (GPCRs) (FFA1, FFA2, FFA3, GPR84 and GPR120). FFA1 and GPR120 are activated by medium- and long chain fatty acids. GPR84 is activated by mediam-chain, but not long chain FFAs. On the other hand, FFA2 and FFA3 are both activated by SCFAs. Tissue distribution studies have indicated that FFA2 and FFA3 function as chemical sensors in the colon. For the involvement of SCFAs in the regulation of colonic motility, propionate and butyrate concentration- -dependently induced phasic and tonic contractions in rat colonic circular muscle. The responses were not observed in mucosal free preparation. Thus, FFA2 and FFA3 are important molecular devices to monitor the chemical composition in colonic lumen. For the local function of SCFAs, it should be stressed that individual SCFA has different mode of actions on colonic smooth muscles. These different effects may be due to the relative contribution of FFA2 and FFA3 on the control of intestinal muscle activity. In this article, we have reviewed the expression and functions of these molecules, especially FFA2 and FFA3 on the regulation of colonic motility.

12

Ecological and rapid control of relevant technological factors of rapeseed oil pressing process

63%

Radzio A., Blaszczyk A., Jasiczak J.

Towaroznawcze Problemy Jakości. Polskie Towarzystwo Towaroznawcze

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2013

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nr 2

13

The metabolic suppressor 3-iodothyronamine enhances lipolysis in 3T3-L1 adipocytes via activation of the adenosine monophosphate-activated protein kinase/forkhead box O1 signaling pathway

63%

Kim M., Park K., Choi I.

Journal of Physiology and Pharmacology

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2020

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tom 71

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nr 3

14

Preliminary screening of lactic and propionic acid bacteria for the synthesis of conjugated linoleic acid [CLA]

63%

Adamczak M., Bednarski W.

Polish Journal of Natural Sciences. Supplement

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2004

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tom 02

7-12

15

The inhibitory activity of long-chain free fatty acids on lactic acid bacteria, yeast and mould

63%

Mutlu T. K.

Polish Journal of Food and Nutrition Sciences

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2011

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tom 61

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nr Suppl.1

16

Impact of nine month health training and a single exercise on changes in ghrelin, leptin and free fatty acids levels in women’s blood

63%

Murawska-Cialowicz E., Wierzbicka-Damska I., Bakonska-Pacon E., Kalwa M., Dziegiel P.

Central European Journal of Sport Sciences and Medicine

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2015

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tom 09

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nr 1

The aim of the research was to assess changes in ghrelin, leptin and free fatty acids (FFA) levels in women’s blood after training. The research was carried out in women aged 45.55 ±11.33 years and with the BMI of 26.49 ±4.49. Health training at 50–66% VO2max took place twice a week for 9 months. In the baseline phase and in the 3rd, 6th and 9th month of the training, body mass and composition were measured, cardiorespiratory fitness was checked after a 10-minute exercise test on a cycloergometer, and fasting levels of ghrelin, leptin and FFA in the serum were assayed and 15 minutes after the exercise test. Body mass was reduced in the 6th month of the training. Fasting ghrelin level increased because of training, leptin and FFA decreased. After single 10-minute exercises performed every 3 months level of ghrelin and FFA increased while leptin decreased. An increase in ghrelin level in the blood after the single exercise can be the result of negative energy expenditure. An increase in fasting ghrelin level after training can be one of the adaptive physiological mechanisms connected with energy saving. A mechanism that is switched on as a result of a long-lasting stimulus that leads to energy losses, reduction in body mass and a decrease in leptin level in the blood.

17

The content of volatile free fatty acids in milk cultured with yoghurt bacteria

63%

Baranowska M.

Polish Journal of Natural Sciences. Supplement

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2004

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tom 02

13-21

18

Modulation of some nuclear matrix enzymatic activities by free fatty acids

63%

Lubocka J., Szopa J., Kozubek A.

Acta Biochimica Polonica

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1995

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tom 42

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nr 2

It was shown that two of main enzymatic activities of plant nucleus and nuclear matrix, namely RNA-polymerasic and DNA-nucleolytic are susceptible to modulation with free fatty acids. The effects observed were dependent to both fatty acid length and degree of unsaturation. In nuclei a stimulation of nuclease activity was observed whereas in matrices short chain fatty acids inhibited the studied activity. The effect of fatty acids on RNA-poIymerase was also different in nuclei and matrices. In nuclei all fatty acids studied inhibited polymerasic activity whereas in matrices short chain fatty acids stimulated this activity by up to 80% and the long chain fatty acids inhibited by up over 70%. The overall alteration of studied activities in nuclei and matrices by unsaturated fatty acids was similar. Nucleolytic activity was stronger inhibited and polymerasic activity was stimulated when the effects of linoleic and linolenic acids were studied. The results suggest possible importance of lipid component in nuclear matrix biological function.

19

The contribution of uncoupling protein and ATP synthase to state 3 respiration in Acanthamoeba castellanii mitochondria

63%

Jarmuszkiewicz W., Czarna M., Sluse-Goffart C., Sluse F. E.

Acta Biochimica Polonica

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2004

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tom 51

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nr 2

Mitochondria of the amoeba Acanthamoeba castellanii possess a free fatty acid-activated uncoupling protein (AcUCP) that mediates proton re-uptake driven by the mitochondrial proton electrochemical gradient. We show that AcUCP activity diverts energy from ATP synthesis during state 3 mitochondrial respiration in a fatty acid-dependent way. The efficiency of AcUCP in mitochondrial uncoupling increases when the state 3 respiratory rate decreases as the AcUCP contribution is constant at a given linoleic acid concentration while the ATP synthase contribution decreases with respiratory rate. Respiration sustained by this energy-dissipating process remains constant at a given linoleic acid concentration until more than 60% inhibition of state 3 respiration by n-butyl malonate is achieved. The present study supports the validity of the ADP/O method to determine the actual contributions of AcUCP (activated with various linoleic acid concentrations) and ATP synthase in state 3 respiration of A. castellanii mitochondria fully depleted of free fatty acid-activated and describes how the two contributions vary when the rate of succinate dehydrogenase is decreased by succinate uptake limitation.

20

Nitric oxide synthase inhibition and elevated endothelin increase oxygen consumption but do not affect glucose and palmitate oxidation in the isolated rat heart

63%

Kurzelewski M., Duda M., Stanley W. C., Baresewicz A.

Journal of Physiology and Pharmacology

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2004

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tom 55

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nr 1,1

Evidence indicates that nitric oxide (NO) suppresses myocardial oxygen consumption (MVO2) and regulates myocardial substrate oxidation, however data from in vivo and isolated heart preparations are conflicting. In addition, cardiac endothelin (ET-1) release has been shown to increase with inhibition of NO synthase (NOS), however the effects of ET-1 on myocardial energetics is not clear. We employed the isolated rat heart model to assess the role of NO and ET-1 on myocardial function and metabolism. Oxidation of glucose and FFA was measured using [U-14C]glucose and [9,10-3H]palmitate. NOS inhibition with NG-methyl-L-arginine acetate salt (L-NMMA, 50 µM), resulted in an increase in MVO2 at a given rate of myocardial external workload, and no change in myocardial glucose or FFA oxidation. ET-1 (25 pM), which caused coronary vasoconstriction similar to that produced by L-NMMA, also increased MVO2 without an effect on cardiac workload, or substrate oxidation, suggesting a role for ET-I in the regulation of myocardial energetics. We assessed also the effect of ETA/ETB receptor blockade (tezosentan; 5 nM) on MVO2 and glucose and FFA oxidation and observed no effect, suggesting that basal ET-1 production does not play a role in regulating MVO2 or substrate selection. In conclusion, inhibition of NOS or the addition of ET-1 resulted in an increase in MVO2, but did not affect glucose or FFA oxidation.

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