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1

Pathogenesis of quinolone-induced arthropathy: A review of hypotheses'

100%
Maslanka T., Jaroszewski J. J., Chrostowska M.
Polish Journal of Veterinary Sciences
|
2004
|
tom 07
|
nr 4
The arthropathogenic effects of quinolones have been described in juvenile animals of multiple species such as dogs, rats, non-human primates, rabbits and guinea pigs. Several studies have been performed to clarify the exact mechanism leading to cartilage damage. In these studies, the investigators focused on the inhibitory effects of quinolones on DNA, collagen and proteoglycan synthesis and on the formation of oxygen-derived reactive molecules. Recently, it was suggested that quinolone-induced arthropathy is possibly associated with the magnesium-chelating properties of quinolones. However, the exact mechanism of quinolone-induced arthropathy is still unkown. This article reviews and summarizes several possible mechanisms for quinolone-induced arthropathy.
2
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Bioequivalence study of two formulations of enrofloxacin following oral administration in chickens

100%
Posyniak A., Zmudzki J., Niedzielska J., Biernacki B.
Bulletin of the Veterinary Institute in Puławy
|
2001
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tom 45
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nr 2
The aim of this study was to demonstrate the bioequivalence of two formulations base on enrofloxacin i.e. between a test formulation Enrofloksacyna 10% per os (Biowet Drwalew) and the reference Baytril 10% (Bayer), according to a framwork required for the registration files. Both formulations were administered in a single oral administration at the recommended dose of 10 mg enrofloxacin per kg of b.w. in chickens. The study was conducted following conventional design, blood samples were collected until 72 h after drug application and analysed by validated method. The plasma disposition kinetics of enrofloxacin in chickens was similar following treatment with both formulations Cmax values (0.92 and 0.98 μg/ml, respectively) and were achieved at the 2nd h after administration of both formulations. None of the estimated pharmacokinetic parameters of both drug formulations were statistically different. Findings show that Enrofloksacyna 10% per os is equivalent to reference Baytril 10%.
3

Analytical procedure for the determination of fluoroquinolones in animal muscle

84%
Posyniak A., Mitrowska K.
Bulletin of the Veterinary Institute in Puławy
|
2008
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tom 52
|
nr 3
A liquid chromatography-fluorescence detection method for the determination of five fluoroquinolones in muscle tissue was proposed. The method is selective and robust enough for the required purposes. The whole procedure was validated in accordance with the Commission Decision 657/2002/EC. Detection capabilities were from 132.8 to 421.0 µg/kg, and recoveries ranged from 51.7% to 80.91%, depending on the analyte.
4

Prospects for development of new antimycobacterial drugs, with special reference to a new benzoxazinorifamycin, KRM-1648

84%
Tomioka H.
Archivum Immunologiae et Therapiae Experimentalis
|
2000
|
tom 48
|
nr 3
5

Antybiotykoterapia u świń cz.5. Charakterystyka fluorochinolonów

67%
Pomorska-Mol M.
Lecznica Dużych Zwierząt. Ogólnopolski Kwartalnik dla Lekarzy Weterynarii
|
2015
|
tom 10
|
nr 3
6

Fluoroquinolones resistance of Campylobacter jejuni and Campylobacter coli isolated from poultry in 1994-1996 and 2005-2008 in Poland

67%
Wozniak A.
Bulletin of the Veterinary Institute in Puławy
|
2011
|
tom 55
|
nr 1
The aim of the research was the determination of resistance to fluoroquinolones (ciprofloxacin and enrofloxacin) of 387 Campylobacter sp. strains isolated from poultry between 1994-1996 (broilers, laying hens) and between 2005-2008 (broilers, laying hens, and turkeys). The resistance was determined by an agar dilution method (MIC), with accordance to Clinical and Laboratory Standards Institute recommendation. Limit concentration for both antimicrobials was measured at ≥ µg/mL. It was demonstrated that during 14 years (1994-2008) there was almost two-fold increase in the number of Campylobacter sp. strains resistant to ciprofloxacin and enrofloxacin. The strains isolated from poultry between 1994-1996 revealed 47.9% and 52.1% resistance to ciprofloxacin and enrofloxacin, respectively, while the percentage of resistant strains among the isolates taken between 2005 and 2008 was measured at 90.2% for ciprofloxacin and 92% for enrofloxacin.
7

Prevalence of mutation in gyrA gene at Thr-86 position in Campylobacter jejuni and Campylobacter coli isolated from poultry and humans

59%
Wozniak A., Kuczkowski M., Chrzastek K., Mazurkiewicz M., Wardak S., Szych J., Wieliczko A.
Bulletin of the Veterinary Institute in Puławy
|
2011
|
tom 55
|
nr 3
The aim of the following research was to analyse the presence of mutation in gyrA gene in C. jejuni and C. coli strains isolated from broilers, laving hens, turkeys collected between 1994-1996 and 2005-2008, and isolated from humans in 2006. The results of the research demonstrated that the highest percentage (100%) of the isolates showing mutation in gyrA gene was observed in Campylobacter coli strains isolated from turkeys between 2005 and 2008.
8

Antybiotyki chinolinowe w zywnosci. Cz.I. Struktura, mechanizm dzialania, farmakokinetyka i toksycznosc

59%
Damasiewicz-Bodzek A., Janoszka B., Bodzek D.
Bromatologia i Chemia Toksykologiczna
|
2007
|
tom 40
|
nr 1
73-77
9

Leczenie zapalenia uszu u psów. Tak wiele możliwości - którą wybrać?

43%
Cole L.
Weterynaria po Dyplomie
|
2019
|
tom 20
|
nr 5
10

Stosowane leki przeciwdrobnoustrojowe w terapii trzody chlewnej w latach 2010-2015 na podstawie Programu Wieloletniego

43%
Krasucka D. M.
Lecznica Dużych Zwierząt. Ogólnopolski Kwartalnik dla Lekarzy Weterynarii
|
2016
|
tom 11
|
nr 4
11

Terapia klinicznych i subklinicznych postaci mastitis

43%
Markiewicz H.
Lecznica Dużych Zwierząt. Ogólnopolski Kwartalnik dla Lekarzy Weterynarii
|
2016
|
tom 11
|
nr 4
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