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Studies were performed on the levator palpebrae superioris muscle, isolated from foetuses aged 17 to 30 weeks. The number of muscle spindles varied from 2 in the 17th week to 7 in the 30th week. The length of the muscle spindles ranged from 20 to 500 mm, and the diameter varied from 10 to 70 μm. These observations show that the number of muscle spindles in levator palpebrae superioris muscles is significantly lesser than that in the extraocular muscles.
The neural arches, transverse processes, spinous processes, and superior and inferior articular processes of each of the 5 lumbar vertebrae can often be found under the common heading of ‘posterior element’. The aim of our study was to assess the changes in geometry of the posterior elements of the foetal lumbar vertebrae during the foetal period. A total of 50 human foetuses, both female and male, from natural abortions, C-R length ranging from 58 to 220 mm, were examined. The methodology of the research included classical anatomical preparation, detailed measurements of the structural elements of the lumbar vertebrae and statistical analysis. Geometrical reconstruction was subsequently performed. The shape of the posterior elements changed gradually from wide and massive to slender. We observed a descending sequence of these alterations, the first vertebra to change being L₁, with L₅ the last. The dynamic of the change was at its greatest during the first 4 weeks of the period evaluated. On the basis of our observations we concluded that the geometry of the posterior elements of the lumbar vertebrae undergoes a process of a great transformation during the foetal period, a process which progresses dynamically until the 14th week of intra-uterine development. The associations with micro-angiogenesis, the ossification process and the notion of structural adaptation of the lumbar spine to heightening mechanical stress are also discussed.
The study was performed on 82 small saphenous veins in human fetuses of both sexes aged 9 to 37 weeks. The earliest valves were observed in 13 week-old fetuses. In fetuses between 13 and 18 weeks old the number of valves increased from 1 to 8. In the older fetuses between 19 and 37 weeks the number of valves varied from 5 to 9 and does not seem to be related to age. During development more valves were found in the upper part of the small saphenous vein. The height of valves increases with age and differs between particular valves of the same vein.
The development of the spiral ganglion was studied in steps sections of 81 human temporal bones. By the 8th week, the spiral ganglion has already separated from the vestibular ganglion. At 13 weeks two distinct populations are observed that correspond to neuron and Schwann cells. At 15 weeks the spiral ganglion has increased its distance from the cochlear duct and is surrounded by mesenchyme near the scala tympani. At 14 weeks a gradual decrease in the nucleus-to-cell area ratio was observed in spiral ganglion neurons that may reflect a morphological adaptation to function. By the 23rd week the modiolus begins to ossify and the spiral ganglion is surrounded by bony trabeculae. The time course of spiral ganglion development follows that of the stria vascularis and organ of Corti, although maturation changes are still observed in the neuronal population even beyond 20 weeks.
With the use of conventional anatomical dissection, radiography, digital and statistical analysis, morphometry and skeletopy of the pancreas was carried out in 60 human foetuses of both sexes (28 female, 32 male) between the 17th and 40th week of intrauterine life. The material was fixed in a 10% formalin solution. The age of the foetuses was determined by crown-rump (CR) lenght measurement on the basis of the Iffy et al. tables. Photographic documentation was made and then digitally processed in the Computer Image Digital Analysis System. The following parameters were taken into account: the length and width of 3 parts of the pancreas, namely the head, corpus and tail. Additionally, radiograms were made to obtain a projection of the gland on the vertebral column. Development of the pancreas was correlated with the age of the foetuses calculated on the basis of crown-rump (CR) lenght measurements. The correlation coefficient with CR was 0.998 for the pancreas length, 0.709 for the width of the head, 0.703 for the width of the corpus and 0.712 for the width of tail. Gender dimorphism was not found (p > 0.05) with regard to the morphometry of the pancreas. In the material under examination the pancreas did not change its position in relation to the vertebral column. The head projected on the vertebral column in the range Th₁₂–L₂ (most frequently L₁–L₂), the corpus on Th₁₂–L₂ and the tail on Th₁₁.
Using computerized tomography 7 human fetuses were examined, aging 24 to 39 weeks. Frontal sinus developes in the region of frontal recess of the frontal nasal meatus in a fetus aging 27 weeks. In the latter weeks of the fetal life the frontal recess of the middle nasal meatus transforms upwards into an oval thin-walled space corresponding to the developing frontal sinus. It adheres to the ethmoidal slabyrinth, integrating with it.
An evaluation was made of the ossification level of the metacarpal and phalangeal bones in human foetuses of both sexes from the 4th to the 9th month of gestation. Our results indicate that ossification of phalangeal bones 1 to 5 always started at the distal end of the phalanx and endochondral ossification prevailed in the proximal phalanx of the thumb.
The aim of the study is to examine the process of change with age of hard and total palate arching. Differences were compared in the arching of the hard and total palate in pairs of twins of the same sex and in pairs of twins of opposite sexes aged between 4 and 7 months of foetal life. On the basis of the results obtained it may be stated that: 1. There is some delay in the process of development of twin foetuses in comparison with ones from a single pregnancy; 2. There are no substantial differences between male and female twins and between twins from heterosexual pairs; 3. Much greater differences take place in older twins with regard to the features under examination.
By means of anatomical and radiological methods and with help of the Computer Digital Image Analysis System the brachiocephalic trunk and the common carotid arteries in relation to the vertebral column were studied in 60 human fetuses. The vessels were found to be between the upper borders: of the third thoracic vertebra and the first cervical vertebra (Th3s-C1s). In the 6th month of the ontogenetic development the vessels descended by one vertebra and established their location in the next prenatal compartment (8-9) between the lower borders: of these same vertebra (Th 3i - C 1i ). We have counted the skeletopic age correlation coefficients of these vessels andfound the diminuation of their values. Sexual skeletopic dimorphisms have not been observed. These investigations have clinical implications.
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