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Etiopathogenesis of allergic diseases

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Allergic diseases are the most common chronic diseases, particularly widely spread among children, adolescents and young adults. The problem is that there is an increasing incidence of allergic diseases. The causes of such a sudden increase of incidence rate are not well known. Complex interactions of environmental factors seem to play their role in the phenomenon. These include: change in the dietary and hygienic habits, progressing industrialization and increased use of numerous chemical agents. It was shown that inhabitants of highly industrialised nations, as compared to those from the developing countries, suffer from allergic diseases more frequently (most often in USA, Australia, Great Britain, Ireland and New Zealand, least frequently in Eastern Europe, Russia, China, India and Ethiopia), inhabitants of cities rather than those of rural areas, children who have no siblings rather than those from large families [1]. Knowledge of the factors that cause or influence the course of allergy is significant as it can help prevent and properly treat this disorder. It seems especially vital as in some patients allergy can manifest itself in the form of severe anaphylactic reactions, including an anaphylactic shock burdened with high risk of death.
Comparison of phytoplankton composition from selected sites in the lower Odra River was done to determine whether the effects of heated water are strongest, from the considered environmental factors. Samples of phytoplankton were collected in April, July and October 2009–2011 at five sites along the lower section of the Odra River. The most pronounced differences between the phytoplankton at the sites were revealed in the phytoplankton abundance and they were related to the time of water retention, the washing out of plankters from slack waters, and the predation by molluscs and zooplankton. The strongest correlations were found between the phytoplankton abundance, the content of inorganic nutrients and temperature. Taxonomic composition of phytoplankton at all sites in the same months was similar. Cooling water from the power plant seems to accelerate eutrophication in the discharge but has no significant impact on the phytoplankton composition downstream in the Odra River.
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Role of silicon in plant resistance to water stress

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Agricultural productivity is strongly affected by different abiotic stresses, among which water stress is the major environmental constraint limiting plants growth. The primary reason for water stress is drought or high salt concentration in soil (salinity). Because both of these stress factors lead to numerous physiological and biochemical changes in plants and result in serious loss in yields, there is a pressing need for finding the effective ways for increasing crops’ resistance to stress factors. One of the alternative methods involving alleviation of negative stress effects might be application of silicon as a fertiliser (root or foliar supply). Many plants, particularly monocotyledonous species, contain large amounts of Si (up to 10% of dry mass). In spite of the high Si accumulation in plants (its amount may equal concentration of macronutrients), until now it has not been considered as an essential element for higher plants. Many reports have shown that silicon may play a very important role in increasing plant resistance to noxious environmental factors. Hence, Si is recognised as a beneficial element for plants growing under biotic and abiotic stresses. The main form of Si which is available and easily taken up by plants is monosilicic acid (H4SiO4). Plants take up Si from soil solution both passively and actively. Some dicotyledonous plants such as legumes tend to exclude Si from tissues – rejective uptake. These plants are unable to accumulate Si and they do not benefit from silicon. Under water stress conditions, silicon might enhance plants’ resistance to stress and ameliorate growth of plants. These beneficial effects may result from better and more efficient osomoregulation, improved plant water status, reduction in water loss by transpiration, maintenance of adequate supply of essential nutrients, restriction in toxic ions uptake and efficient functioning of antioxidative mechanisms. Based on the current knowledge and presented data, it can be concluded that the role of Si in plants is not restricted to formation of physical or mechanical barrier (as precipitated amorphous silica) in cell walls, lumens and intercellular voids. Silicon can also modulate plants’ metabolism and alter physiological activities, particularly in plants subjected to stress conditions. However, in some plants, increased silicon supply does not improve plant growth. Hence, a better understanding of the interactions between silicon application and plant responses will contribute to more efficient fertiliser practices, especially under stress conditions.
The aim of the study was to analyze the mangrove vegetation in relation to environmental factors with a view to offering explanations for variations in the structural characteristics of the mangroves. Multiple regression analysis was used as the analytical tool to predict vegetation response to the environment. Salinity, soil magnesium and bulk density were the most important determinants of overstorey mangrove structure while tidal flood, exchangeable cations and topography were important in the understorey. The groundlayer stratum was determined by substrate texture, tidal flood and topography.
This work concerns the influence of temperature, the presence (lack of oxygen and different carbohydrates) on solubilization of tribasic calcium phosphate, iron phosphate and Thomas basic slag in samples of bottom sediments of gyttja, sapropel, "dy" and tyrfopel types from lakes of different trophic lakes of the Mazurian Lake District. In samples of 4 types of bottom sediments more PO4-P from phosphate compounds gathered at 25° C than at lower temperatures in situ in lakes; besides, there were more in anaerobic conditions than in aerobic ones, in bottom sediments samples with Ca3(P04)2 more PO4-P gathered at pH 4-5, in samples with FeP04 at pH 5-6, in samples with Thomas basic slag at pH 4-6. More PO4-P was in samples of bottom sediments with addition of glucose, saccharose, mannose and arabinose, less with the addition of xylose and cellobiose independently from used phosphate compounds. Greater amounts of PO4-P gathered in the samples of bottom sediments of gyttja and sapropel types, lower in the samples of "dy" and tyrfopel types. In all series of the experiments the highest amounts of P04-P gathered in a logarythmic phase of the development of natural population of bacteria.
The influence of the presence of bacteriophage ZD5, temperature, pH and the interaction of these factors on survival of Y. enterocolitica cells in pond water and buffers was examined. The presence of bacteriophage ZD5 and temperature have substantial influence on survival of Y. enterocolitica cells in buffers with different pHs. The statistical analysis showed a significant influence of the presence of phage ZD5 on the decrease in the number of Y. enterocolitica cells incubated in buffers with pHs 6, 7, and 8. In the presence of phage ZD5, pH itself turned out to be of no significance because the average numbers of Y. enterocolitica cells obtained in pHs 6, 7, and 8 did not differ significantly at p≤0.05. Statistical analysis confirms significant influence of the presence of phage ZD5 on the reduction of the number of Y. enterocolitica cells in pond water at both 4°C and 20°C. The lowest average value of the number of cells was obtained at 4°C in the presence of phage ZD5, both in the tested buffers and in the pond water.
Bacteria can adapt to various environmental factors such as temperature, pressure, ions, nutrients and toxic substances by modifying their membranes to maintain them in a fluid state. These modifications within the cytoplasmatic membrane particularly result from changes in the fatty acid composition and interaction between proteins and lipids. Fatty acids, mainly phospholipid fatty acids, play a role as a good biomarker of changes of physiological status of microorganisms caused by external factors. A greater understanding of the detailed physiological mechanisms of bacterial membrane lipid adaptation, especially to toxic substances and solvents, are important for researchers who use bacteria in bioremediation and biotransformation processes.
The study was conducted to examine some factors affecting speed of Thoroughbred horses competing at Polish racecourses. Data on horses’ speed (m/s) in flat races from year 2001 to 2005 comprised 12,643 records for 1,543 Thoroughbred horses competing in 1,876 races. Statistical analysis accounted for fixed effects of distance, age, sex, trainer, competition (defined as number of horses competing within one horse length from the winner at the moment of crossing the finishing line), track condition, weight carried, number of runners in a race and for the random effect of race, rider and horse. Almost all the factors included in the linear model were highly significant (P<0.01), but distance × competition test revealed a significant difference (P<0.05). Average speed of Polish Thoroughbreds and mean distance of the races was 15.57 m/s and 1509.1 m, respectively. Speed of horses decreased when racing distance increased and males were faster than females. Three-year-old horses ran faster (LSM=15.29 m/s) than the 2-year-olds (LSM=15.26 m/s) but slower than 4-year-old and older horses (LSM=15.36 m/s). Condition of the racing track resulted in a difference in Racine speed of 1.13 m/s between fast and heavy assessed track. Least squares mean (LSM) of the Speer without competition between horses was 15.23 m/s, and increased to 15.33 m/s and 15.36 m/s when there were one and two competing horses, respectively. The increase in speed due to competition was highest in 1000 m races. Speed did not significantly differ between one or two competing horses,except at the distance of 1200 m. The horses carrying more weight during a race showed a flower speed (P<0.01). Speed was 0.02 m/s higher for each additional horse in a race. The random race effect was the largest, while the random rider effect the smallest component of variance.
Leaf carbon isotope composition (δ¹³C) of both vascular and non-vascular plants were investigated in order to assess their variability along an altitude gradient (414, 620, 850, 1086, 1286 and 1462 m) from a subtropical monsoon forest located at Mt. Tianmu Reserve, eastern China. Leaf δ¹³C values of all plant species ranged from -34.4 to -26.6‰, with an average of -29.8‰. There is no significant difference in leaf δ¹³C between vascular plants and mosses, however, trees had significantly higher δ¹³C values than herbs. For pooled data, leaf δ¹³C was positively correlated with altitude. Leaf δ¹³C was significantly and negatively correlated with annual mean temperature and atmospheric pressure, while it was significantly and positively correlated with soil water content. Furthermore, there was no relationship between leaf δ¹³C and soil nitrogen content or soil phosphorus content. The altitudinal trend in leaf δ¹³C is the consequence of the interaction between temperature, atmospheric pressure and soil water content.
Zmiany w składzie starzejącego się ludzkiego ciała są przedmiotem zainteresowania zarówno gerontologów jak i geriatrów; odzwierciedlają czynniki genetyczne i środowiskowe, takie jak aktywność fizyczna, żywienie i choroba, jak również fizjologiczne procesy starzenia się. Istnieje wiele dostępnych metod umożliwiających zrozumienie różnych przedziałów u ludzi. Badania nad składem ciała w wyższej grupie wiekowej prowadziliśmy w tym samym laboratorium przez około dwadzieścia lat stosując czteroprzedziałowy model przy wykorzystaniu całkowitej zawartości w organizmie potasu oraz wody. Błędy, którymi obarczone są takie metody, zostały dokładnie przedyskutowane w innych pracach. Prospektywne badania składu ciała, przeprowadzone w ramach tej pracy, u tych samych mężczyzn i kobiet od wieku 70 do 81 lat wykazały spadek ciężaru ciała podczas tego dziesięciolecia u obu płci, średnio o 7 kg u mężczyzn i 6 kg u kobiet. Ten spadek ciężaru ciała mógł być częściowo spowodowany obniżeniem zawartości tłuszczu. Zmiany w zawartości tłuszczu w ciele były jednak zbyt małe, by osiągnąć znamienność statystyczną. Co się tyczy masy komórkowej ciała, nasze badania wykazały, że utrata ciężaru ciała u mężczyzn bardziej odpowiada utracie masy komórkowej, natomiast u kobiet bardziej utracie tłuszczu. W tym kontekście warto zauważyć, że ćwiczenia fizyczne kończyn dolnych, włączając ćwiczenia siłowe, są skuteczne także u osób starszych. Ponadto, wyniki kilku prac badawczych wykazały, że zastosowanie wysiłku fizycznego może być efektywną metodą zapobiegającą utracie zawartości mineralnej kości i osteoporozie. W naszej pracy najważniejszą przyczyną spadku ciężaru ciała podczas ósmej dekady życia był spadek zawartości wody w ciele, głównie wody pozakomórkowej.
Schizophrenia manifests itself primarily with positive symptoms, negative symptoms and cognitive disorders. Animal models of mental diseases seem to be an important tool in understanding key theories related with pathophysiology of the disorder and are used to assess efficacy of new drugs. References describe four basic groups of animal models of schizophrenia, such as: models created by pharmacological intervention, genetic models, lesion models and models of developmental disorders of primary brain structures. Of the models referred to above, the group of developmental disorder models is particularly noteworthy, as they are primarily easy to use, and the methods are highly sensitive. High scientific value of these models is associated with the neurodevelopmental theory which stipulates that at an early stage of body development, a number of interactions between genetic and environmental factors may affect the development of neurons which may cause disorders of brain cytoarchitecture development.We review six developmental models of schizophrenia in rats (MAM - methylooxymethanol acetate, prenatal stress, maternal deprivation, isolation rearing, prenatal immune challenge and maternal malnutrition) that are all validated by disruption in PPI.
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