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Great strides have been made in the last decade regarding the importance of both genetic and environmental contributors to the risk for heavy drinking, alcohol problems, and alcohol use disorders. This lecture reviews recent research fi ndings regarding important endophenotypes contributing to these risks, (e.g. low response to alcohol, personality traits, sweet liking). Genetic fi ndings will highlight several genes that appear to contribute to the level of response to alcohol, sweet liking and some personality traits predisposing to alcohol seeking behavior. This presentation will review ongoing steps to identify additional genes in several large population studies. The lecture will also briefl y describe neurobiological background of drugs: (1) registered for alcohol treatment – disulfi ram, naltrexon, acamprosate, (2) off label drugs used in alcohol dependence: topiramat and ondasetron and (3) new medication: nelmelfene. Also, the approach of using the existing alcohol typologies (proposed by Cloninger and Lesch) in treatment proposal will be presented using our own data. Supported by MNiSW grant nr N N402 189335
Background. Caffeine is a commonly found ingredient in many beverages. Its main dietary source is coffee, cola drinks and in recent years, energy drinks. Objectives. To compare the consumption of drinks containing caffeine (coffee, colas and energy drinks) and the reasons and circumstances under which they were drunk by middle school (junior high school) pupils and university students. Material and methods. Surveyed subjects were 90 middle school pupils from Warsaw and Kutno together with 100 students attending the Warsaw University of Life Sciences (SGGW). A questionnaire, designed by the authors, was used to determine the amounts, frequency and the reasons or circumstances in which coffee, colas and energy drinks were consumed. Statistics used, consisted of the Mann-Whitney U and Chi-square (χ2) tests, with significance taken as α ≤ 0.05. Results. Cola drinks were found to be the most popularly consumed beverages containing caffeine; 97% pupils and 93% students. Coffee was however drunk twice less by pupils compared to students, whilst similar amounts of energy drinks were consumed by both groups; respectively 48% and 53%. Gender differences were observed for the energy drinks with young men drinking the most. Coffee and energy drink consumption also rose with age by respectively 39% and 57%. The mean caffeine intake in pupils and students were respectively estimated to be 141 and 163 mg/day(d). The reasons why these beverages were drunk varied, from drinking coffee to keeping awake and drinking cola because of its good taste. Pupils also drank energy drinks due to its taste but students because of improved mental performance and in staying awake. Conclusions. Drinking caffeine containing drinks by adolescents can be very variable and comes from many different sources. Thus, its intakes may be very high and so require monitoring, particularly for the youngest. Further observational studies are needed to assess the consumption of energy drinks in relation to physical activity.
The article aims at the increasing of knowledge among young people coming from the country, studying at various types of schools – from the aspect of frequency of their drinking, age of alcohol initiation and preferences towards alcoholic drinks. We examined 5,000 young people from rural areas in Lublin province between the ears 2002- 2004. A screening questionnaire that included AUDIT test (the Alcohol Use Disorders Identifi cation Test) was used. The AUDIT was developed by the WHO to identify hazardous and harmful alcohol consumption. The results showed that both frequency and alcohol initiation age were related to type of school and sex of young people. We found that young people from rural areas of Lublin province do not differ from all-Polish trends in relation to these patterns. Some changes in the alcohol consumption model in Polish villagers were noted. Young people in the country clearly prefer beer drinks. Restrictions regarding alcohol sales to young people are not complied with. In almost half of the group we found alcoholism in families. Our fi ndings show that antialcoholic prophylaxis should be initiated in the fi rst years of childrens’ education. Preventive programmes should be based not only on school, but also on the family.
The aim of the study was the examination of the eating habits of the randomly select groups living in Brno city in the Czech Republic. Study conducted 59 information scientists (41 men, 18 women, aged 18-24 years). The group was questioned about place of eating, how often a day they consumed, if they're controlling their drinking pattern and the sufficiency of vitamins in meals. From the answers obtained was emerged that their consumption habits were not good. The main insufficiencies were the low frequency of meals during a day and an insufficient liquid intake.
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