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1
Content available remote

Acute anti-fibrillating and defibrillating potential of atorvastatin, melatonin, eicosapentaenoic acid and docosahexaenoic acid demonstrated in isolated heart model

100%
Benova T., Knezl V., Viczenczova C., Bacova B. S., Radosinska J., Tribulova N.
Journal of Physiology and Pharmacology
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2015
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tom 66
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nr 1
2

Discrepancy between clinical and histological effects of DHA supplementation in a rat model of pouchitis

84%
Drzymala-Czyz S., Banasiewicz T., Tubacka M., Tarasiuk-Rusek A., Majewski P., Drews M., Walkowiak J.
Folia Histochemica et Cytobiologica
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2012
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tom 50
|
nr 1
3
Content available remote

Docosahexaenoic acid inhibits ethanol/palmitoleic acid-induced necroptosis in AR42J cells

84%
Ku L., Lee J., Lim J. W., Jin L., Seo J. T., Kim H.
Journal of Physiology and Pharmacology
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2020
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tom 71
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nr 3
4
Content available remote

Peroxisome proliferator-activated receptor alpha activation inducesunfavourable changes in fatty acid composition of myocardial phospholipids

84%
Baranowski M., Blachnio-Zabielska A., Gorski J.
Journal of Physiology and Pharmacology
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2009
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tom 60
|
nr 2
13-20
Peroxisome proliferator-activated receptor alpha (PPAR) plays a crucial role in the transcriptional regulation of myocardial lipid metabolism. In vitro studies on isolated cardiomyocytes showed that PPAR activation induces expression of numerous genes involved in virtually all steps of fatty acid catabolism. However, there is very few data on the effect of PPAR activation on the content and composition of myocardial lipids in vivo. Therefore, our main aim was to examine effects of selective PPAR agonist WY-14643 on the content and fatty acid composition of major lipid classes in the heart of rats fed a standard chow (STD) or a high-fat diet (HFD). In STD rats WY-14643 paradoxically decreased palmitate oxidation rate in the heart, however, in HFD animals such effect was not observed. WY-14643 markedly reduced myocardial free fatty acid and diacylglycerol content in STD rats, whereas in HFD group the opposite effect was observed. These changes reflected alterations in plasma lipid concentration which suggests that effects of WY-14643 on the heart were indirect and secondary to changes in plasma lipid availability induced by the drug. Basal myocardial glucose uptake was not affected by PPAR agonist in either group, however, glycogen content in the heart was markedly increased. WY-14643 exerted profound influence on the fatty acid composition of myocardial phospholipids in both diet groups. These changes included increased percentage of monounsaturated fatty acids and replacement of n-3 polyunsaturated fatty acids (PUFA) by those from the n-6 family. This action of WY-14643 might be detrimental to the heart since n-3 PUFA possess cardioprotective and antiarrhythmic properties.
5

Neuronal nitric oxide synthase phosphorylation induced by docosahexaenoic acid protects dopaminergic neurons in an experimental model of Parkinson’s disease

67%
Parlak H., Ozkan A., Dilmac S., Tanriover G., Ozsoy O., Agar A.
Folia Histochemica et Cytobiologica
|
2018
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tom 56
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nr 1
6
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Content available

Seasonal proximate and fatty acid variations of some seaweeds from the Northeastern Mediterranean coast

67%
Polat S., Ozogul Y.
Oceanologia
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2013
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tom 55
|
nr 2
7

Docosahexaenoic acid provides protective mechanism in bilaterally MPTP-lesioned rat model of Parkinson's disease

67%
Hacioglu G., Seval-Celik Y., Tanriover G., Ozsoy O., Saka-Topcuoglu E., Balkan S., Agar A.
Folia Histochemica et Cytobiologica
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2012
|
tom 50
|
nr 2
8

The effects of fish oil microcapsules on quality of potato dish

67%
Domiszewski Z., Bienkiewicz G., Tarnowiecka-Kuca A., Zywicki S., Tokarczyk G., Krawczynska W., Hrebien-Filisinska A., Rogalewska M., Synowiec E., Laskowska A.
Electronic Journal of Polish Agricultural Universities. Series Food Science and Technology
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2013
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tom 16
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nr 2
9

The effects of docosahexaenoic acid on glial derived neurotrophic factor and neurturin in bilateral rat model of Parkinson's disease

67%
Tanriover G., Seval-Celik Y., Ozsoy O., Akkoyunlu G., Savcioglu F., Hacioglu G., Demir N., Agar A.
Folia Histochemica et Cytobiologica
|
2010
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tom 48
|
nr 3
10

Sklad kwasow tluszczowych mleka kobiecego

59%
Karwowska W., Duda G., Obiedzinski M., Kroc M.
Bromatologia i Chemia Toksykologiczna
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2005
|
tom 38
|
nr Supl.
105-109
The dietary components used by 102 breast-feeding women included in the study were reflected in the content of fatty acids in their breast-milk. Fatty acid profile in the milk was changing during lactation. Higher correlation ratios were found between the proportion of fatty acids in the analysed samples of human colostrum and the supply of fatty acids in the diet of women during pregnancy, when compared to mature milk. An inhibitory effect of trans fatty acids upon the synthesis of long-chain unsaturated fatty acids from their precursors, the linoleic acid and alpha-linoleic acid was observed.
11

Stopien oddzialywania produktow utleniania tluszczu na zmiany ilosciowe dostepnej lizyny i metioniny w ukladach modelowych o zroznicowanym odczynie srodowiska

43%
Hes M., Korczak J., Gorecka D., Gramza A., Jedrusek-Golinska A.
Bromatologia i Chemia Toksykologiczna
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2005
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tom 38
|
nr Supl.
455-460
W pracy określano podatność aminokwasów występujących w postaci jonu obojnaczego i postaci kationu na reakcje z produktami utleniania tłuszczu. Prowadzono badania modelowe w emulsjach estrów metylowych kwasów tłuszczowych: dokozaheksaenowego, linolowego, oleinowego i stearynowego.
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