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  1. 10 Folia Histochemica et Cytobiologica

  2. 4 Acta Biologica Cracoviensia. Series Zoologia

  3. 2 Bromatologia i Chemia Toksykologiczna

  4. 2 Folia Histochemica et Cytobiologica. Supplement

  5. 1 Acta Biochimica Polonica

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  1. 7 Gacko M.

  2. 6 Karwowska A.

  3. 5 Minarowska A.

  4. 4 Krol T.

  5. 3 Famulski W.

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  1. 1 2021

  2. 1 2018

  3. 1 2012

  4. 1 2011

  5. 1 2010

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1

Regulatory role of cathepsin D in apoptosis

100%
Minarowska A., Miarowski L., Karwowska A., Gacko M.
Folia Histochemica et Cytobiologica
|
2007
|
tom 45
|
nr 3
2

Immunohistochemical evaluation of cathepsin D expression in colorectal cancer

88%
Chabowski A., Sulkowska M., Sulkowski S., Famulski W., Skrzydlewska E., Kisielewski W.
Folia Histochemica et Cytobiologica
|
2001
|
tom 39
|
nr 2
3

Tumor budding intensity in relation to cathepsin D expression and some clinicopathological features of colorectal cancer

88%
Guzinska-Ustymowicz K., Famulski W., Sulkowska M., Chabowski A., Zalewski B., Sulkowski S., Gnojnicki J.
Folia Histochemica et Cytobiologica. Supplement
|
2001
|
tom 39
|
nr 1
4

Molecular characterization, tissue distribution, and expression profiling of the CTSD gene during goose ovarian follicle development

75%
Zhu J., Hu S., Lu Y., Rong Y., Qing E., Li L., Wang J.
Folia Biologica
|
2021
|
tom 69
|
nr 1
5

Asymmetric peptidomimetics containing L-tartaric acid core inhibit the aspartyl peptidase activity and growth of Leishmania amazonensis promastigotes

75%
Santos A. L. S., Matteoli F. P., Sangenito L. S., Branquinha M. H., Cotrim B. A., Resende G. O.
Acta Parasitologica
|
2018
|
tom 63
|
nr 1
6

Effect of heavy metal cations on the activity of cathepsin D (in vitro study)

63%
Karwowska A., Lapinski R., Gacko M., Grzegorczyk E., Zurawska J., Karczewski J. K.
Folia Histochemica et Cytobiologica
|
2012
|
tom 50
|
nr 3
7
Content available remote

Stress-induced enhancement of activity of lymphocyte lysosomal enzymes in pigs of different stress-susceptibility

63%
Stojek W., Borman A., Glac W., Baracz-Jozwik B., Witek B., Kamyczek M., Tokarski J.
Journal of Physiology and Pharmacology. Supplement
|
2006
|
tom 57
|
nr 8
61-72
To evaluate a possible mechanism of stress-induced lymphopenic effect we assessed the activity of lymphocyte lysosomal enzymes (LE) under immobilization. The effects of immobilization stress on LE (AP, acid phosphatase, cathepsin D and L, ß-N-acetyl-glucosamidase) activity in lymphocytes, number of lymphocytes and plasma cortisol (COR) level in the peripheral blood were examined in the cross-bred Pietrain pigs showing genotypic (presence or lack of RyR1 gene mutation) and phenotypic (reactivity to halothane) differences. It was found that immobilization stress evoked an increase in LE which was concomitant with lymphopenia and a rise of COR level. The most pronounced enhancement of LE, which may reflect a tendency to lymphocyte cytolysis, was found in the recessive homozygotes RyR1 (nn) phenotypically defined as stress/halothane susceptible as well as in the heterozygotes RyR1 (Nn) included in the group of stress/halothane resistant. Despite this individual variability the stress-induced increase in LE activity was present in all the animals. It seems that a possibility of destruction (lysis) of lymphocyte cells should not be excluded as one of the causes of stress lymphopenia.
8

Quantitative determination and localization of cathepsin D and its inhibitors

63%
Minarowska A., Karwowska A., Gacko M.
Folia Histochemica et Cytobiologica
|
2009
|
tom 47
|
nr 2
153-177
9

The activity and immunoexpression of cathepsin D in rat male reproductive organs

63%
Burdan F., Szumilo J., Dudka J., Dabrowski A., Maciejewski R., Wojtowicz Z.
Folia Morphologica
|
2006
|
tom 65
|
nr 2
111-115
Cathepsin D is a cysteine endopeptidase that belongs to the lysosomal enzyme family. The aim of the study was to evaluate the enzyme immunoexpression and activity in selected male genital organs in mature Wistar rats. The activity of cathepsin D was measured spectrophotometrically in homogenates of the testis, epididymis, seminal vesicle and prostate. Immunohistochemical staining was also performed in the ductus deferens. Enzyme activity was found in the following sequence: testis>epididymis>dorsal prostatic lobe>seminal vesicle>lateral prostatic lobe>ventral prostatic lobe. Although there were differences in enzyme activity between various organs of the male reproductive system, cathepsin D immunoreactivity was seen exclusively in the Sertoli and Leydig cells in the testis.
10

Expression of syndecan-1 and cathepsins D and K in advanced esophageal squamous cell carcinoma

63%
Szumilo J., Burdan F., Zinkiewicz K., Dudka J., Klepacz R., Dabrowski A., Korobowicz E.
Folia Histochemica et Cytobiologica
|
2009
|
tom 47
|
nr 4
11

The activity of cathepsin D in saliva of cystic fibrosis patients

63%
Minarowska A., Minarowski L., Karwowska A., Sands D., Dabrowska E.
Folia Histochemica et Cytobiologica
|
2007
|
tom 45
|
nr 3
12

Cathepsin D and cathepsin L activities in the wall of aortic aneurysm and parietal thrombus determined by means of synthetic substrates

63%
Gacko M., Worowska A., Glowinski S.
Bulletin of the Polish Academy of Sciences. Biological Sciences
|
2000
|
tom 48
|
nr 1
13

CD44 expression in colorectal cancer. An immunohistochemical study including correlation with cathepsin D and some tumour clinicopathological features

63%
Zalewski B., Famulski W., Sulkowska M., Piotrowski Z., Kisielewski W., Guzinska-Ustymowicz K.
Folia Histochemica et Cytobiologica. Supplement
|
2001
|
tom 39
|
nr 1
14

The effects of dehydroepiandrosterone on the activity of selected lysosomal enzymes in mice from different age groups

51%
Krol T., Lysek-Gladysinska M., Lach H., Kochman K., Trybus W., Staszczyk K., Mycinska M., Kopacz-Bednarska A., Trybus E., Wieczorek A., Gren A.
Acta Biologica Cracoviensia. Series Zoologia
|
2008
|
tom 50
37-42
15

Human cathepsin D

51%
Minarowska A., Gacko M., Karwowska A., Minarowski L.
Folia Histochemica et Cytobiologica
|
2008
|
tom 46
|
nr 1
23-38
16

Cathepsin D inhibitors

51%
Gacko M., Minarowska A., Karwowska A., Minarowski L.
Folia Histochemica et Cytobiologica
|
2007
|
tom 45
|
nr 4
291-313
17

Kainate-evoked modulation of gene expression in rat brain

51%
Kaminska B., Filipkowski R. K., Biedermann I. W., Konopka D., Nowicka D., Hetman M., Dabrowski M., Gorecki D. C., Lukasiuk K., Szklarczyk A. W., Kaczmarek L.
Acta Biochimica Polonica
|
1997
|
tom 44
|
nr 4
Kainate is a glutamate analog that produces neuronal excitation resulting in seizures within hours following its intraperitoneal injection into adult rats. Then, at 2-3 days after the treatment, neurodegeneration of apoptotic character can be observed in limbic system. As a consequence, plastic reorganization and glial reactivation phenomena occur. These physiological and pathological responses are reflected by specific changes in gene expression, that can be dissected according to their spatio-temporal patterns. The early phase of gene expression observed in all hippocampal subfields appears to reflect a sudden burst of spiking activity. Changes in mRNA levels restricted to dentate gyrus are suggestive of a link to neuronal plasticity. The late gene expression response implies its correlation either to neuronal cell death or glial reactivation, depending on cellular localization of gene products. Thus analysis of the temporal and spatial gene expression pattern in the hippocampus after kainate treatment may provide clues revealing specific phenomena to which gene expression could be attributed.
18

Influence of retinoids on the lysosomal system in mouse liver

51%
Krol T.
Acta Biologica Cracoviensia. Series Zoologia
|
2000
|
tom 42
19

Biochemical and ultrastructural changes in mouse hepatocytes after encumbrance with Iscador

51%
Krol T., Wieczorek A., Lysek-Gladysinska M., Witek B., Lach H., Pierzchala-Koziec K., Gren A.
Acta Biologica Cracoviensia. Series Zoologia
|
2003
|
tom 45
20

Activity of the lysosomal system in mouse liver after hydrocortisone administration

51%
Krol T., Kolataj A.
Acta Biologica Cracoviensia. Series Zoologia
|
2000
|
tom 42
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