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1

Anatomical variation of sciatic nerve division in the popliteal fossa and its implication in popliteal nerve blockade

100%
Saleh H. A. M., El-fark M.M.O., Abdel-Hamid G. A.
Folia Morphologica
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2009
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tom 68
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nr 4
256-259
The sciatic nerve (SN) originates from the L4–S3 roots in the form of two nerve trunks: the tibial nerve (TN) and the common peroneal nerve (CPN). The TN and CPN are encompassed by a single epineural sheath and eventually separate (divide) in the popliteal fossa. This division of the SN occurs at a variable level above the knee and may account for frequent failures reported with the popliteal block. We studied the level of division of the SN in the popliteal fossa and its relationship to the common epineural sheath of the SN. The level of division of the SN sheath into TN and CPN above the knee was measured in 30 cadaver specimens. The SN was invariably formed of independent trunks (TN and CPN) encompassed in one common epineural sheath. The SN divided at a distance range of 50 to 180 mm above the popliteal fossa crease. The present findings suggest that the TN and CPN leave the common SN sheath at variable distances from the popliteal crease. This finding and the relationship of the TN and CPN sheaths may have significant implications for popliteal nerve block. (Folia Morphol 2009; 68, 4: 256–259)
2
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Cerebral angiogenesis after subarachnoid hemorrhage (SAH) and endothelin receptor blockage with BQ-123 antagonist in rats

100%
Josko J., Hendryk S., Jedrzejowska-Szypulka H., Slowinski J., Gwozdz B., Lange D., Snietura M., Zwirska-Korczala K., Jochem J.
Journal of Physiology and Pharmacology
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2001
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tom 52
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nr 2
3

Sensitization of the rewarding effects of morphine: effects of AMPA glutamate receptor blockade

84%
Aguilar M. A., Manzanedo C., Ribeiro Do Couto B., Rodriquez-Arias M., Minarro J.
Acta Neurobiologiae Experimentalis
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2005
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tom 65
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nr 5
4
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
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The effect of PGF2 alpha-estrumate on the secretion and composition of abomasal juice in sheep during H2-histaminic receptor blockade with cimetidine

84%
Dejneka J., Lukaszewska J., Paradowski L., Zalucki G.
Acta Physiologica Polonica
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1987
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tom 38
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nr 4
5
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Blockade of calcium channels and AT1 receptors prevents the hypertensive effect of calcilytic NPS 2143 in rats

67%
Rybczynska A., Jurska-Jasko A., Boblewski K., Lehmann A., Orlewska C.
Journal of Physiology and Pharmacology
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2010
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tom 61
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nr 2
Calcilytics, antagonists of calcium receptor, decrease sensitivity of this receptor to plasma calcium concentration and increase parathyroid hormone (PTH) secretion. Moreover, it was recently indicated that calcilytic NPS 2143 induces hypertension in rats. This study tested whether the increase of mean arterial blood pressure (MAP) induced by NPS 2143 administration is mediated by calcium channel and angiotensin II type1 (AT1) receptor activity. Wistar rats were anaesthesized with Thiopental i.p. and infused i.v. with saline supplemented with the anaesthetic. Blood pressure was monitored continuously in the carotid artery. Effects of NPS 2143 administered i.v. as bolus on MAP in the presence and absence of felodypine and losartan were investigated. Both, felodipine and losartan pretreatment provoked a persistent MAP decrease by 18±3 and 14±3 mmHg, respectively. Infusion of NPS 2143 at 1 mg/kg b.w. confirmed hypertensive activity of calcilytic and increased blood pressure for 21±4 mmHg. In contrast, administration of NPS 2143 in felodipine as well as in losartan pretreated rats did not change MAP as compared to felodipine/control and losartan/control groups, respectively. Our study indicated that both the blockade of calcium channels and the AT1 receptor activity prevented the hypertensive effect of calcilytic NPS 2143. This finding might be particularly important in understanding the mechanisms that mediated blood pressure changes related to the activity of calcium receptor.
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