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The influence of nanodiamond particles on rat health status

100%

Szmidt M., Niemiec T., Sawosz-Chwalibog E., Mitura K.

Annals of Warsaw University of Life Sciences - SGGW. Animal Science

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2013

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tom 52

The objective of the present investigation was to evaluate the effect of nanodiamond (ND) particles on rats health status. 1 mg/kg b.w. of nanodiamond particles was administrated intravenously and intraperitoneum. The presence of an adverse impact was examined. The results show significant changes in biochemical (glucose and total protein level decrease) and hematological (elevated platelets count) parameters, only in case of intravenous injection.

2

Nephrotoxicity of tetrabromobisphenol-A in rats after repeated exposure

100%

Frydrych B., Szymanska J. A.

Bromatologia i Chemia Toksykologiczna

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2001

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tom 34

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nr 1

In this study the attempt to assess nephrotoxicity of TBBF-A after repeated exposure was made, on the basis of selected biochemical parameters.

3

Phenol degradation by bacteria. Part one: Isolation and characterization of bacterial strain

100%

Dluhy M., Rybarikova D., Bales V.

Polish Journal of Environmental Studies

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1996

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tom 05

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nr 2

An effective microorganism for phenol degradation process was selected and isolated from the natural environment using basic screening. The tested strain Alcaligenes xylosoxidans ssp. denitrificans was compared in vital activity experiments to the CCM strain Pseudomonas putida 3423 in order to obtain optimal biochemical parameters and to find out the right way of cultivation for the preparation of an inoculum. The efficiency of phenol degradation at higher concentrations is strongly influenced by microorganism age and, of course, by the initial substrate concentration. The time of biodegradation with the increase of initial phenol concentration was increased, but to the critical concentration was independent of it. The method of preparation of an inoculum with highly induced oxygenase system was found. A suitable composition of the broth medium for precultivation and cultivation of tested microorganisms has resulted from this work.

4

Effect of linear alkylbenzene sulfonate on some biochemical parameters in rainbow trouts [Oncorhynchus mykiss]

100%

Turkmen G.

Medycyna Weterynaryjna

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2004

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tom 60

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nr 05

5

Experimental studies on effect of sodium fluoride and nitrate on biochemical parameters in rats

100%

Zabulyte D., Uleckiene S., Kalibatas J., Paltanaviciene A., Jascaniniene N., Stosik M.

Bulletin of the Veterinary Institute in Puławy

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2007

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tom 51

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nr 1

The aim of the study was to investigate the effects of sodium fluoride (NaF) and nitrate (NO₃⁻) either administered orally alone or in a combination, on the biochemical parameters of rats. Tests on general toxicity were conducted on the basis of methodical recommendations 408 of the Organisation for Economic Co-operation and Development Guideline for Testing of Chemicals: "Subchronic Oral Toxicity - Rodent: 90-d Study".The following combined effects of the tested chemicals were predominantly observed: additive, synergistic, and antagonistic. Methaemoglobinaemia was noted in groups given NO₃⁻ or NaF + NO₃⁻ complex.

6

Hepatoprotective and antioxidant activity of Lannea coromandelica Linn. on thioacetamide induced hepatotoxicity in rats

86%

Srinivasa Rao V., Wilkin Einstein J., Das K.

International Letters of Natural Sciences

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2014

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tom 03

Hepatoprotective and antioxidant activity of Lannea coromandelica bark extract (LCBE) was investigated on thioacetamide induced hepatotoxicity in rats. Hepatotoxicity was induced by thioacetamide (TAA) administration (100 mg/kg. s.c). LCBE at different doses (400 and 200 mg/kg) were administered orally to male wistar rats. Thioacetamide caused elevation of serum concentration of AST, ALT, ALP, serum bilirubin and also reduced serum concentration of total protein, albumin, sodium, potassium in animals as compared to control (p < 0.05) but LCBE treated rats showed maximum reduction of AST [(138±5.1) IU/L], ALT [(71 ±2.7) IU/L], ALP [(140 ±1.9) IU/L] with the high dose (400 mg/kg bw) of combined aqueous and alcoholic bark extract. Whereas, serum bilurubin, cholesterol, sugar and LDH content were varied with the treatments but showed higher with the only ethanolic extract at dose of 400 mg/kg. The IC50 value was observed as (83.28 ±2.12) μg/mL, for DPPH radical scavenging activity. Result concluded that ethanolic extract and combined aqueous and alcoholic bark extract of L. coromandelica showed a potential hepatoprotective and antioxidant activities might be due to the presence of phenolic groups, terpenoids and alkaloids.

7

Comparison of selected morphological, rheological and biochemical parameters of winter swimmers’ blood at the end of one winter swimming season and at the beginning of another

86%

Teleglow A., Marchewka J., Tabarowski Z., Rembiasz K., Glodzik J., Scislowska-Czarnecka A.

Folia Biologica

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2015

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tom 63

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nr 3

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Comparison between immuno-clinicopathological features of experimental and human visceral leishmaniasis by Leishmania donovani

86%

Saini S., Dube A., Sahasrabuddhe A. A., Thakur C. P., Joshi S., Rawat K., Rai A. K.

Acta Parasitologica

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2020

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tom 65

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nr 1

9

Does the site of blood collection in fish affect haematological and blood biochemical results?

86%

Bojarski B., Socha M., Drag-Kozak E., Rombel-Bryzek A., Kapinos S., Szala L., Kondera E., Lugowska K., Witeska M.

Folia Biologica

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2021

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tom 69

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nr 2

10

Platelets and the clinical course of Crohn's disease

86%

Padysz M., Stec-Michalska K., Banasik J., Gasiorowska A.

Health Problems of Civilization

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2018

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tom 12

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nr 4

Background. Crohn’s disease (CD) is a chronic, autoimmune, inflammatory bowel disease (IBD) characterised by periods of exacerbations and remissions. Autoimmune disorders caused by undetermined factors lead to inflammation in the intestinal mucosa. Presently, there is a growing interest in the role of platelets in the assessment of inflammatory lesions in CD. Accordingly, the aim of this study was to answer the question of whether routinely measured platelet indices: concentration of platelets (PLT), the mean platelet volume (MPV), plateletcrit (PCT) could become biomarkers for monitoring the course of CD. Material and methods. In the study programme, there were enrolled 100 patients with a diagnosed CD with a different clinical course, disease location and heterogeneous therapy. In all patients, there were collected blood and stool samples for the assessment of CRP, blood count and fecal calprotectin evaluation. The clinical state of each patient was classified using the Harvey-Bradshaw index. Results. The study showed a positive, statistically significant correlation between fecal calprotectin, CRP, WBC, the Harvey-Bradshaw index and the number of platelets and PCT. Furthermore, the analysis showed a statistically significant negative correlation between MPV and the number of WBC, CRP and fecal calprotectin. Conclusions. Our study showed that platelet indices are a valuable, non-invasive and widely accessible method to assess mucosal healing and the clinical status of the patient.

11

Relationship between the degree of dehydration and the balance of acid-based changes in dehydrated calves with diarrhoea

86%

Guzelbektes H., Coskun A., Sen I.

Bulletin of the Veterinary Institute in Puławy

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2007

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tom 51

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nr 1

The aim of the study was to investigate acid-base changes and to determine some serum biochemical parameters in dehydrated calves with diarrhoea according to the degree of dehydratation. Thirty diarrhoeic dehydrated calves submitted to treatment in the university clinic, were used in the study. The calves were accessed as suitable for this study, if they were moderately or severely dehydrated according to clinical symptoms. All sick calves had the usual yellow and watery diarrhoea. Calves with 4% to 8% dehydration (moderate) had a weak suckle reflex, dry mucous membranes, warm mouth and partly good muscular tone. Calves with 10% and above dehydration (severe) were unable to stand, and had no suckling reflex and cold mouth. The mean pH, base excess, chloride (only severely dehydrated group) and sodium were -significantly decreased in both moderately and severely dehydrated groups. On the other hand, potassium, phosphorus, HCO₃⁻ and anion gap levels were increased, compared to that of the control group. Results of this study showed that there was a relationship between the base excess and anion gap, with a degree of clinical dehydration. However, there may not be an exact correlation between the degree of dehydration and the severity of acidosis. Based on the clinical symptoms, the results of this study could be a useful tool under field conditions, in estimating the base excess in diarrhoeic dehydrated calves, when acidosis therapy is needed.

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Effects of chelidonine on some biochemical parameters in the serum of rats subacutely intoxicated by copper

86%

Jagiello-Wojtowicz E., Piatkowska-Chmiel I.

Herba Polonica

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2004

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tom 50

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nr 3-4

The study was investigated the effects of 10-day treatment with chelidonine (50 and 100 mg/kg ip) on the concentration of creatinine and urea in the blood serum of rats subacutely intoxicated by copper. Subacute intoxication with copper chloride has been found to cause a significant decrease in the urea level and no effect 011 the creatinine level. Chelidonine had virtually 110 effect on the parameters examined except for the decrease in urea in the dose of 50 mg/kg as compared with the control group. 10-day treatment with both doses of chelidonine significantly decreased the level of creatinine and increased the level of urea (dose 100mg/kg) in the serum of intoxicated rats.

13

The influence of quercetin on some biochemical parameters in rats exposed to environmental contamination with fluorine compounds

86%

Czerny B., Put A., Mysliwiec Z., Juzyszyn Z.

Polish Journal of Environmental Studies

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2000

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tom 09

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nr 3

Male Wistar rats were exposed for 3 and 6 months to NH4F in a toxicological chamber. Some animals received sodium salts of quercetin sulfonic acids at a dose of 5 or 20 mg/kg body weight. It was found that quercetin alleviates biochemical changes in the liver caused by ammonium fluoride, in particular concerning enzyme activities and lipid metabolism.

14

Effects of propylene glycol supplementation on blood biochemical parameters in dairy cows

86%

Mikula R., Nowak W., Jaskowski J. M., Mackowiak P., Pruszynska E., Wlodarek J.

Bulletin of the Veterinary Institute in Puławy

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2008

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tom 52

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nr 3

The objective of this study was to determine the effect of propylene glycol supplementation as powder top dressing during the transition period on selected blood parameters in dairy cows and to evaluate the optimum time of the administration of this glucose precursor. Forty-eight Holstein-Fresian cows were divided into four groups: control with no glycol supplementation, glycol administered from day 14 before parturition until calving, glycol supplemented from calving to day 14 postpartum, and glycol fed from day 14 prepartum to day 14 of lactation. Blood samples were collected three weeks and then one week before parturition and on 14th, 56th, and 70th d of lactation, then concentrations of glucose, non-esterified fatty acids, cholesterol, triglycerides, insulin, and the activity of aspartate aminotransferase and γ-glutamyl transpeptidase were analysed. Propylene glycol, which was supplemented as top dressing during transition period, had no major effects on biochemical variables throughout this period. However, there was observed a positive glycol effect on glucose concentration and the activity of aspartate aminotransferase during lactation.

15

Reactivity of the immunological system of turkeys vaccinated with the Newcastle virus after intoxication with carbaryl

86%

Wojcik R., Swiecicka-Grabowska G.

Polish Journal of Veterinary Sciences

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2004

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tom 07

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nr 1

Research has shown that among pesticides, carbaryl is one of the strongest immunosuppressors for numerous animal species. In this paper, the effect of carbaryl on biochemical parameters and on specific and non-specific immunity in carbaryl-intoxicated birds was determined. The results indicate a significant immunosuppressive effect in turkeys, on almost all the investigated biochemical parameters and on the indices of specific and non-specific immunity. The only exception is a slightly elevated level of total protein and reactivity of T lymphocytes to non-specific mitogen in the group of intoxicated birds.

16

Effects of acute and 10-day treatment with protopine-type alkaloids from Chelidonium majus L. on some biochemical parameters in rats

86%

Jagiello-Wojtowicz E., Maciejewska-Kozak H., Chodkowska A.

Herba Polonica

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2000

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tom 46

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nr 4

Badano wpływ ostrego i 10-dniowego podawania ip alkaloidów protopinowych: allokryptopiny protopiny na aktywność aminotransferaz ALT i AST, a także oznaczano poziom a-fetoproteiny (AFP) oraz ß2-mikroglobuliny w surowicy krwi szczurów. Stwierdzono, że protopina zastosowana szczurom jednorazowo zwiększała, bądź zmniejszała aktywność AST. Protopina podawana przez 10 dni istotnie zwiększała, aktywność AST i pozostawała bez wpływu na aktywność ALT. Allokryptopina podana jednorazowo w dawce 0,1 LD50 istotnie zmniejszała, natomiast podawana przez 10 dni pozostawała bez wpływu na aktywność obu aminotransferaz. Oba badane alkaloidy nie wpływały na poziom AFP i ß2-mikroglobuliny.

17

Effect of 10-day treatment with Padma 28 on some biochemical parameters in rats acutely intoxicated with cadmium chloride

86%

Jagiello-Wojtowicz E., Jeleniewicz K., Chodkowska A., Saj E.

Herba Polonica

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2004

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tom 50

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nr 2

The aim of the study was to investigate the effect of 10-day treatment (i.p.) with Padma 28 on the levels of a-fetoprotein and ß2-microglobulin and the activities of aminotransferases ALT and AST in the serum of cadmium-poisoned rats (dose of 0.36 mg/kg i.p.). It was found that acute intoxication with cadmium chloride significantly enhanced AFP and ß2-microglobulin levels and did not affect the activity of ALT and AST in the serum of rats in comparison with the control group. Padma 28 administrated for 10-days only in the dose of 1 mg/kg significantly decreased AFP and in the doses of 0.1 and 1 mg/kg increased ß2-microglobulin levels while it did not affect the activity of ALT and AST in the serum of cadmium-poisoned rats. 10-day treatment with Padma 28 has been found to increase nephrotoxic effects of cadmium in rats acutely intoxicated with this metal.

18

The effect of toxic and heliophysical factors on the biochemical parameters of the external mucus of carp, [Cyprinus carpio L.]

86%

Lebedeva N., Vosyliene M. Z., Golovkina T.

Archives of Polish Fisheries

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2002

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tom 10

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nr 1

The dynamics of the biochemical parameters of the external mucus of carp Cyprinus carpio L. exposed to 1 μM concentrations of heavy metal salts (CuSO₄·5H₂O Pb(NO₃)₂ and ZnSO₄·7H₂O) were studied. The biochemical parameters of external mucus (specific weight, pH, total protein, hemoglobin, ketones) were measured during exposure at 1, 3, 6, 24 h and regularly during a 21-day post-exposure period. Significant changes in hemoglobin and total protein concentrations were determined during the period of exposure to heavy metals and after it. Correlations of changes in biochemical parameters of mucus with the intensity of some parameters of sun activity and radio radiation flow were found during the post-exposure period. It was concluded that it is necessary to assess the possible complex effects of various origin and the magnitude of environmental factors on fish.

19

Physiological values of selected serum biochemical indices in chickens

86%

Krasnodebska-Depta A., Koncicki A.

Polish Journal of Veterinary Sciences

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1999

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tom 02

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nr 2

This paper deals with normal values of some serum biochemical parameters in chickens and laying hens with regard to their age and sex. Investigations were performed on clinically healthy multipurpose birds of the Astra S race, both females and males aged 1-23 and 1-18 weeks, respectively. In serum of blood collected from the animals, levels of total protein, glucose, total cholesterol, triglycerides, calcium (Ca) and inorganic phosphorus as well as the activity of some enzymes including aspartate aminotransferase (AST), alkaline phosphatase (AP), lactate dehydrogenase (LDH) and creatine kinase (CK) were determined. In the birds of both sexes, some parameters were found to be age-dependent, including levels of total protein (increasing with age), cholesterol and triglycerides and CK activity (the highest levels were noted in 1-week old animals) as well as inorganic phosphorus and AP activity (decreasing with age). In the females beyond the 14th week of age, sex-dependent changes included an increase in levels of total protein, triglycerides and Ca as well as a higher level of phosphorus than that found in the males. No correlation between glucose level, AST, LDH activity, and the age and sex of the birds was observed.

20

Influence of age on biochemical parameters in calves

86%

Jezek J., Klopcic M., Klinkon M.

Bulletin of the Veterinary Institute in Puławy

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2006

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tom 50

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nr 2

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