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1

The immunoradiometric assay for tumor necrosis factor-alpha is an alternative indicator for its bioactivity

100%
Van den Bemb G. C. M.
Applied Biology Communications. Lublin Scientific Center
|
1992
|
tom 02
|
nr 5
2

Probing the structural origins and mechanism of the bioactivity of food polysaccharides

75%
Morris V. J.
Polish Journal of Food and Nutrition Sciences
|
2011
|
tom 61
|
nr Suppl.1
3

Culturable endophytes diversity isolated from Paeonia ostii and the genetic basis for their bioactivity

75%
Yang R.-H., Zhang S.-W., Xue D., Xuan J.-H., Zhang Y.-B., Peng B.-B.
Polish Journal of Microbiology
|
2018
|
tom 67
|
nr 4
Paeonia ostii is known for its excellent medicinal values as Chinese traditional plant. To date, the diversity of culturable endophytes associated with P. ostii is in its initial phase of exploration. In this study, 56 endophytic bacteria and 51 endophytic fungi were isolated from P. ostii roots in China. Subsequent characterization of 56 bacterial strains by 16S rDNA gene sequence analysis revealed that nine families and 13 different genera were represented. All the fungal strains were classed into six families and 12 genera based on ITS gene sequence. The biosynthetic potential of all the endophytes was further investigated by the detection of putative polyketide synthase (PKS) and nonribosomal peptide synthetase (NRPS) genes. The PCR screens were successful in targeting thirteen bacterial PKS, five bacterial NRPS, ten fungal PKS and nine fungal NRPS gene fragments. Bioinformatic analysis of these detected endophyte gene fragments facilitated inference of the potential bioactivity of endophyte bioactive products, suggesting that the isolated endophytes are capable of producing a plethora of secondary metabolites. These results suggest that endophytes isolated from P. ostii had abundant population diversity and biosynthetic potential, which further proved that endophytes are valuable reservoirs of novel bioactive compounds.
4

26 kD TNFalpha precursor molecule and 17 kD mature TNFalpha form differentiate the clinical status of the patients with ling-standing diabetes mellitus of type I

75%
Zorena K., Mysliwska J., Semetkowska-Jurkiewicz E., Lukaszuk K., Mysliwski A.
Folia Histochemica et Cytobiologica
|
1997
|
tom 35
|
nr 2
5

Bioactivity of grapevine (Vitis vinifera L.) chemicals and products: focus on antioxidant power

63%
Iriti M., Vitalini S.
Polish Journal of Food and Nutrition Sciences
|
2011
|
tom 61
|
nr Suppl.1
6

The influence of sterilization with EnbioJet microwave flow pasteurizer on composition and bioactivity of blueberry honeysuckle juice

63%
Kusznierewicz B., Piekarska A., Paszowska M., Matusik O., Poleska-Muchlado Z., Bartoszek A.
Polish Journal of Food and Nutrition Sciences
|
2011
|
tom 61
|
nr Suppl.1
7

Expression, purification, and bioactivity of a soluble recombinant ovine interferon-tau in Escherichia coli

63%
Yu H.-Y., Gao D.-M., Zhou W., Xia B.-B., He Z.-Y., Wu b., Jiang M.-Z., Wang M.-L., Zhao J.
Journal of Veterinary Research
|
2021
|
tom 65
|
nr 1
8

Chemometrics in ecological studies

63%
Szafranek B., Malinski E., Szafranek J.
Bulletin of the Polish Academy of Sciences. Biological Sciences
|
2002
|
tom 50
|
nr 1
9
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Gastroprotective effects of flavonoids in plant extracts

51%
Zayachkivska O. S., Konturek S. J., Drozdowicz D., Konturek P. C., Brzozowski T., Ghegotsky M. R.
Journal of Physiology and Pharmacology. Supplement
|
2005
|
tom 56
|
nr 1
219-231
The purpose of this paper is to overview the relations between plant-originated substances and their bioactivity measured in terms of antioxidant, cytoprotective and antiulcer activities. In addition, we assessed whether these compounds are capable of affecting the gastric mucosal lesions induced by absolute ethanol applied intragastrically (i.g.). The following plant-originated flavonoid substances were considered; Solon (Sophoradin extract), Amaranth seed extract, grapefruit-seed extract (GSE) and capsaicin (extract of chilly pepper). The area of gastric mucosa lesions and gastric blood flow were measured in rats with ethanol-induced lesions without (control) and with one of the tested substances without and with capsaicin denervation of afferent nerves or administration of L-nitro-arginine (L-NNA), an inhibitor of nitric oxide synthase (NOS). Male Wistar rats, weighing 180-220 g fasted for 24 h before the study where used 100% ethanol was applied i.g. to induce gastric lesions, whose area was determined by planimetry. Gastric blood flow was assessed using electrolytic regional blood flowmeter. All tested plant-originated substances afforded gastroprotection against ethanol-induced damage and this was accompanied by increase in gastric microcirculation, both changes being reversed by pretreatment with neurotoxic dose of capsaicin or by pretreatment with L-NNA. We conclude that plant-originated flavonoid substances are highly gastroprotective probably due to enhancement of the expression of constitutive NOS and release of NO and neuropeptides such as calcitonin gene related peptide (CGRP) released from sensory afferent nerves increasing gastric microcirculation.
10

Bioactivity of Bowman Birk inhibitors in thermally processed orange juice

51%
del Castillo M. D., Amigo-Benavent M., Bravo L.
Polish Journal of Food and Nutrition Sciences
|
2011
|
tom 61
|
nr Suppl.1
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