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Severe leaf spot disease was observed on Aloe vera plants in the winters of 2011 and 2012 during a survey of various nurseries of Gwalior, India. Irregular, sunken, dark creamish brown spots having reddish brown margin were noticed on both surfaces of the leaves. The causal organism was consistently isolated from symptomatic leaves on potato dextrose agar media (PDA). A total 59 isolates of fungi were recovered from diseased A. vera leaves, and 37 isolates were identified as belonging to the genus Fusarium. On the basis of morphological characteristics and internal transcribed spacer (ITS) region of rDNA amplified using the primers ITS4/ITS5 the pathogen was identified as Fusarium proliferatum (Matsushima) Nirenberg and pathogenicity of the isolate was confirmed by using Koch’s postulates. To the best of our knowledge, this is the first report of leaf spot disease caused by Fusarium proliferatum on A. vera plants in India.
This study was conducted to investigate the effects of crude Aloe vera polysaccharide (AVP) on the growth performance and immune function of weaned piglets. A total of 200 (Landrace Yorkshire × Duroc) weaned pigs at 21 d with initial 8.88 ± 0.49 kg body weight (BW) were allotted to one of four dietary treatments in a randomized complete block design according to their sex and BW (5 replicates with 10 pigs per pen, 5 gilts and 5 barrows). Dietary treatments included one basal diet, and three diets with AVP supplementation (0.05%, 0.1%, or 0.2%). Average daily gain (ADG), average daily feed intake (ADFI), and feed:gain (F:G) ratios were calculated at the end of the experiment. Separated serum samples from each treatment were assayed at the end of the experiment for the concentrations of cytokines and the blocking rate of antibodies against classical swine fever virus (CSFV). Supplementation of AVP at 0.1% improved (P < 0.05) ADG compared with the control group. No significant differences in ADFI or F:G were observed between AVP-treated and untreated control piglets. All AVP-treated pigs had a significantly lower incidence of diarrhoea (P < 0.05) when compared with control pigs. Feeding AVP resulted in increasing (P < 0.01) IL-2 and IFN-γ (at 0.1% and 0.2%) and IL-4 (at 0.05%, 0.1% and 0.2%), and in no significant changing of IL-10 (P > 0.05). Supplementation of AVP at 0.05%, 0.1% and 0.2% increased (P < 0.01) the blocking rate of antibodies against CSFV. These results indicate that dietary supplementation with dietary AVP enhanced growth performance in weaned piglets by improving immune function, decreasing the incidence of diarrhoea
Modern medicine, as well as the pharmaceutical, cosmetic and food industries appreciate the value of plant raw materials for their antiseptic, analgesic, anti-inflammatory and soothing effects. Medicinal plants, often found endemically, are often treated as potential sources of new substances with antimicrobial and antifungal activity. The aim of this study was to analyze the significance of selected medicinal and spice plants in terms of their ability to inhibit the growth of microorganisms, including those pathogenic to humans. The significance of active substances contained in selected plant species with high antimicrobial potential including Aloe vera L. and Chelidonium majus L. was described. The antimicrobial activity of plant oils, including those extracted from citrus and spice plants, was also analyzed. Plants are a rich source of many substances with a broad spectrum of activity. This knowledge has often been used in folk medicine, but it was not until the development of modern research methods that the mechanisms underlying the therapeutic properties of many plant substances and their proper use could be understood. New substances present in plant materials are constantly being discovered that may be of medical interest because of their great potential to be used against microorganisms or because of their antioxidant and anti-cancer properties.
Angiogenesis, the formation of new capillaries from pre-existing vascular network, plays an important role in physiological and pathological processes such as embryonic development, wound healing, and development of atherosclerosis. Extension of the circulatory network is also considered to be one the most important factors during cancerogenesis. Inhibition of angiogenesis may lead to inhibition of tumor growth whereas stimulation may improve wound healing. Research achievements suggest the use of plants and their extracts as potential therapeutic agents with pro- or antiangiogenic activity. Since the anticancer and antiangiogenic properties of many phytomedicines have been amply reviewed elsewhere this paper will focus on the treatment of vascular insufficiency in wound healing. Globally accepted herbal drugs are thought to be safe and effective, however, there is a need for more evidence-based confirmation in controlled and validated trials. Among the most frequently studied proangiogenic phytochemicals are ginsenosides from Panax ginseng, beta-sitosterol from Aloe vera, calycosin from Radix Astragali, and extracts from Hippophae rhamnoides L. and Angelica sinensis.
The paper has aimed to determine total polyphenol compound content and antioxidant ac­tivity of fresh aloe leaves and aloe preparations obtained experimentally and manufactured. Research material constituted fresh sieved aloe leaves, aloe gel obtained experimentally from the leaf inner, pulp made of sieved aloe leaf skin and manufactured aloe gel - a diet supplement. Most of polyphenol compounds were found in skin of aloe (390.8 mg/100 g) which showed the highest antioxidant activity (6.6 jumol ofTrolox in 1 g of skin). The next position was deserved to whole leaves (213.2 mg of GAE in 100 g of preparation - 4.2 ¿umol ofTrolox in 1 g of leaves). The next was aloe gel obtained in laboratory (94.9 mg of GAEin 100 g of gel -0.9jUmol ofTrolox in 1 g of gel). The least polyphenol compounds (34.6 mg of GAE in 100 g of preparation) and the lowest antioxidant activity (0.13 jumol ofTrolox in 1 g of preparation) were in manufactured aloe gel. After calculating these values in dry mass a similar antioxidant activity of whole aloe leaf and preparations obtained experimentally (gel and skin) was determined. It was almost 4 times lower in manufactured gel.
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