Wyniki wyszukiwania

1

Behavioral effects of apomorphine during development of rats

100%

Brus R., Herman S., Jamrozik Z.

Acta Physiologica Polonica

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1977

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tom 28

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nr 3

2

Cardiovascular system reactivity to catecholamines during ontogenetic development of dogs and rats

88%

Brus R., Lenartowicz H., Korczak-Dziuba K., Monsiol A., Jamrozik Z.

Acta Physiologica Polonica

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1975

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tom 26

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nr 6

3

Nonverbal deficits in explicit and implicit memory of Parkinson's disease patients

76%

Gawrys L., Szatkowska I., Jamrozik Z., Janik P., Friedman A., Kaczmarek L.

Acta Neurobiologiae Experimentalis

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2008

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tom 68

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nr 1

This study examined verbal and nonverbal aspects of explicit and implicit memory in a sample of 19 Parkinson's disease (PD) patients and 21 control subjects. For implicit memory evaluation, we used a Mirror Reading (MR) task employing verbal material as well as a nonverbal Serial Reaction Time (SRT) task. For explicit memory measurement we applied a word pairs task (verbal) and pairs of a Japanese ideograms task (nonverbal). The PD patients displayed impairments in the nonverbal tasks only, namely, in the SRT task and the pairs of Japanese ideograms task. No correlation between Wisconsin Card Sorting Test (WCST) scores and the results of tasks in which PD patients displayed deficits (SRT and pairs of Japanese ideograms) were discovered. Interestingly, such a correlation was found in the case of MR and words pairs tasks, which did not distinguish PD patients from control group.

4

Parkinson's disease leads to distorted interaction of episodic and working memory systems

51%

Gawrys L., Szatkowska L., Pilacinski A., Piatkowska-Janko E., Bogorodzki P., Wolak T., Friedman A., Sienkiewicz J., Koziorowski D., Janik P., Jamrozik Z., Krolicki L., Andrysiak R., Kulinski R., Kaczmarek L.

Acta Neurobiologiae Experimentalis

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2009

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tom 69

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nr 3

Patients with Parkinson’s disease (PD) exhibit impairments in executive function and working memory. As opposed to motor symptoms of the disease the physiological origins of cognitive defi cits are not well understood. The aim of the present study was to delineate mechanisms of cognitive impairment in PD using blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI). Twenty-two patient and 10 matched control subjects accomplished Wisconsin Card Sorting Test (WCST) – standard clinical measure of executive function and then underwent fMRI during performance of the N-Back working memory task.The correlation analysis comparing BOLD signal intensity changes with number of categories achieved in WCST revealed a signifi cant positive correlation within supramarginal gyrus, inferior parietal gyrus, middle and inferior frontal gyrus and caudate nucleus. Signifi cant negative correlations with executive impairment were observed within fusiform and parahippocampal gyrus, as well as enthorhinal and perirhinal cortex. These results suggest that cognitive impairment in PD may origin in consequence of distorted interaction between episodic and working memory systems.

Ograniczanie wyników

2 Acta Neurobiologiae Experimentalis

2 Acta Physiologica Polonica

4 Jamrozik Z.

2 Brus R.

2 Friedman A.

2 Gawrys L.

2 Janik P.

2 Kaczmarek L.

1 Andrysiak R.

1 Bogorodzki P.

1 Herman S.

1 Korczak-Dziuba K.

1 Koziorowski D.

1 Krolicki L.

1 Kulinski R.

1 Lenartowicz H.

1 Monsiol A.

1 Piatkowska-Janko E.

1 Pilacinski A.

1 Sienkiewicz J.

1 Szatkowska I.

1 Szatkowska L.

1 Wolak T.

1 2009

1 2008

1 1977

1 1975

Behavioral effects of apomorphine during development of rats

Cardiovascular system reactivity to catecholamines during ontogenetic development of dogs and rats

Nonverbal deficits in explicit and implicit memory of Parkinson's disease patients

Parkinson's disease leads to distorted interaction of episodic and working memory systems