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1

Pochodne pleuromutyliny i ich zastosowanie w lecznictwie weterynaryjnym

100%
Kowalski C., Zan R., Rolinski Z.
Medycyna Weterynaryjna
|
2004
|
tom 60
|
nr 01
22-26
2

Tempo eliminacji 8-alfa-hydroksymutyliny, markera pozostalosci tiamuliny, u swin

100%
Zan R., Kowalski C., Rolinski Z., Burmanczuk A.
Medycyna Weterynaryjna
|
2006
|
tom 62
|
nr 04
448-451
Tiamulin, a semi-synthetic antibiotic agent, is exclusively used in veterinary medicine and is rapidly distributed in the body and intensively metabolized in the liver. The aim of the study was to estimate the residue levels of tiamulin metabolite in pigs. tissues after oral and intramuscular administration. The experiment was carried out on 38 pbz breed weaners, divided into two groups. One of the groups was administered Tiamowet 45% granulate orally at a dose of 24 mg/kg b.w./day, and the other was administered Tiamowet 200 intramuscularly at a dose of 15 mg/kg b.w./day. Both drugs were taken for 5 days. The weaners from both groups were slaughtered on days 3, 4, 6, 8, 10, 12 and 15 following the end of drug administration. Samples of tested tissues from the livers and muscles were isolated in order to measure the residue marker level. 8-α-hydroxymutilin residues were estimated according to the GC method by Marcus and Sherma in their own modification. A validation method procedure was also carried out. The GC experiment showed that 8-a-hydroxymutilin concentration in the tested muscles attains a lower level than that of MRL i.e. 100 µg/kg on day 10 following intramuscular Tiamowet 200 preparation administration and on day 12 following oral Tiamowet 45% granulate administration.
3

Oxalic acid degradation by a novel fungal oxalate oxidase from Abortiporus biennis

100%
Graz M., Rachwal K., Zan R., Jarosz-Wilkolazka A.
Acta Biochimica Polonica
|
2016
|
tom 63
|
nr 3
4

Concentration of cefacetril in milk after its intramammary administration to cows with healthy and inflammed mammary gland

100%
Burmanczuk A., Rolinski Z., Kowalski C., Zan R.
Bulletin of the Veterinary Institute in Puławy
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2011
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tom 55
|
nr 4
The aim of the study was to develop a sensitive analytical method that enables to determine cefacetril concentration in milk after its application to the udders, as well as to establish and compare cefacetril’s basic pharmacokinetic indicators after its intramammary application to cows with inflammed and healthy udders. The content of cefacetril was determined with the use of high-performance liquid chromatography with UV detection. Usefulness of the developed analytical method in the studies of pharmacokinetics of cefacetril has been demonstrated. Results obtained during the statistical analysis and bacteriological examinations allowed to regard the antibiotic as an accurately selected medical product used in the treatment of mastitis in cows.
5

Czynniki warunkujace rozwoj agroturystyki w gminie Koden

100%
Buraczynska D., Gasiorowska B., Zan R.
Monografie. Akademia Podlaska w Siedlcach
|
2006
|
nr 75
94-104
6

Pharmacokinetics of tylosin in broiler chickens

100%
Kowalski C., Rolinski Z., Zan R., Wawron W.
Polish Journal of Veterinary Sciences
|
2002
|
tom 05
|
nr 3
7

Walidacja metody oznaczania 8-alfa-hydroksymutyliny w materiale biologicznym

100%
Zan R., Kowalski C., Burmanczuk A.
Medycyna Weterynaryjna
|
2006
|
tom 62
|
nr 07
797-800
A validation method is a key element in both the elaboration of reference methods and the assessment of a laboratory's competence in producing reliable analytical data. The aim of the study was to validate the GC method (according to Marcus and Sherma), which is used in determining 8-α-hydroxymutilin in a biological matrix (swine tissues: liver and muscles). The fundamental parameters for validation, including accuracy, precision, selectivity, sensivity, reproductibility and stability, were estimated. The studies confirmed the usefulness of the GC method for determining tiamulin residues in swine tissues.
8
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Leczenie toksycznych uszkodzeń wątroby u psów i kotów przy użyciu antyoksydantów

100%
Zan R., Rolinski Z., Kowalski C., Burmanczuk A.
Życie Weterynaryjne
|
2013
|
tom 88
|
nr 05
9

Melatonina, potencjalnie nowy lek przeciwnowotworowy u zwierząt

100%
Zan R., Rolinski Z., Kowalski C., Burmanczuk A.
Medycyna Weterynaryjna
|
2012
|
tom 68
|
nr 06
The article describes the possibility of using melatonin in cases of neoplastic diseases in animals. Most observational studies show an association between melatonin and cancer in animals and humans. The mechanisms by which melatonin may act in this way have not been fully elucidated. The oncostatic action of melatonin in mammary cancer, as well as in uterine and prostate cancer, may result from the modulating effect on the enzymes involved in the local synthesis of estrogens. Many biological effects of melatonin, including antitumor activity, are caused by the activation of membrane receptors (MT1 and MT2), connected with regulatory proteins (G proteins). Other possible anti-cancer mechanisms include anti-angiogenic activity, anti-inflammatory activity, protection from oxidative damage, and immunostimulation. Many studies confirm the efficacy and safety of melatonin in cancer treatment. Melatonin can be used with chemotherapy in animals not only to support the action of anticancer drugs, but also to reduce their toxicity.
10

Czy melatonina jest niezbędna również dla zwierząt?

100%
Zan R., Rolinski Z., Kowalski C., Duda M.
Magazyn Weterynaryjny
|
2011
|
tom 20
|
nr 03
11

Pharmacokinetic - pharmacodynamic model and ampicillin residue depletion after intramammary administration in cows

100%
Burmanczuk A., Rolinski Z., Kowalski C., Zan R.
Journal of Veterinary Research
|
2016
|
tom 60
|
nr 2
12

Activity of β-lactam antibiotics against certain microorganisms which cause mastitis in cows

88%
Brumianczuk A., Kowalski C., Rolinski Z., Zan R., Krasucka D.
Journal of Veterinary Research
|
2016
|
tom 60
|
nr 3
13
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
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Właściwości biologiczne melatoniny i jej zastosowania kliniczne u zwierząt

88%
Zan R., Rolinski Z., Kowalski C., Burmanczuk A., Polska B.
Życie Weterynaryjne
|
2011
|
tom 86
|
nr 03
14

Farmakokinetyka linkomycyny oraz ocena biorownowaznosci preparatu Lincomycinum 11 procent z preparatem Lincocin 40 procent po stosowaniu doustnym u warchlakow

88%
Kowalski C., Rolinski Z., Burmanczuk A., Zan R., Lodkowski R.
Medycyna Weterynaryjna
|
2004
|
tom 60
|
nr 03
307-309
15

Porownanie farmakokinetyki oksytetracykliny stosowanej w postaci proszku i granulatu u swin

88%
Kowalski C., Rolinski Z., Pomorska M., Zan R., Krasucka D.
Medycyna Weterynaryjna
|
2005
|
tom 61
|
nr 02
188-190
16

Rhizobium strains differ considerably in outer membrane permeability and polymyxin B resistance

76%
Komaniecka I., Zamlynska K., Zan R., Staszczak M., Pawelec J., Seta I., Choma A.
Acta Biochimica Polonica
|
2016
|
tom 63
|
nr 3
17

Uspokajające i przeciwlękowe działanie melatoniny w niektórych przypadkach zaburzeń behawioralnych u psów i kotów

76%
Zan R., Rolinski Z., Kowalski C., Zadrzynska I., Andrychiewicz J., Duda M., Opielak G.
Medycyna Weterynaryjna
|
2013
|
tom 69
|
nr 02
Melatonin (MT), a hormone synthesized in the pineal gland, regulates a number of physiological processes in mammals. The range of clinical applications of the synthetic analogue of the hormone in both humans and animals is increasing. This paper, based on our observations, describes the applicability of MT in tablets in various cases of abnormal behavior of cats and dogs. Cases in which the efficacy of MT was confirmed include, among others, the animal’s anxiety caused by excessive noise, by being left alone at home, and by transportation. Other disturbances in which the drug can be applied include excessive excitability of cats and dogs in the postoperative period resulting in breaking the stitches or licking fresh surgical wounds, as well as various types of stereotypies, such as the animal chasing its own tail, dermatitis caused by obsessive licking, or aggression towards other animals or the owner. An additional argument in favor of applying MT in cats and dogs is its virtual non-toxicity.
18
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Content available

Pharmacokinetics and pharmacodynamics of a single dose of sustained-release azithromycin formulation in pigeons

64%
Zan R., Burmanczuk A., Stepien-Pysniak D., Gajda A., Gbylik- Sikorska M., Posyniak A., Kowalski C., Grabowski T.
Polish Journal of Veterinary Sciences
|
2020
|
tom 23
|
nr 1
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