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Due to the great danger of the collision of oil tankers, lots of research on the collision of oil tankers has been carried out. But, at present, the research on the collision of oil tankers mainly focuses on the loading condition of the struck ship, ignores the impact on the loading condition of the striking ship. However, during the actual oil tanker collision, the striking ship is generally in the state of loading. Therefore, it is necessary to carry out the analysis of the impact of the loading condition of the striking ship on the collision damage of the oil tanker. In this paper, the effect of striking ship with loading on the impact performance of the side structure during the collision of the cargo double hull oil tanker has been investigated. The ship collision model was established by using the finite element software ANSYS/LS-DYNA which is based on 7000 tons of double hull oil tankers. Based on the analysis of the collision force, impact of striking speed changes, impact of striking deep changes and structural energy absorption during the collision process, the influence of the striking ship with loading on the damage mechanism and the impact performance of the double shell oil ship side structure was expounded. The results show that the influence of the striking ship with loading can be great to the damage to side hull during the research of the collision performance of the oil tanker
Background: Oncogenic Notch1 is known to activate the NF-κB pathway in T cell acute lymphoblastic leukemia (T-ALL) and to up-regulate the transcription of Asb2α, a specificity factor for an E3 ubiquitin ligase complex that plays an important role in hematopoietic differentiation. Therefore, we hypothesize that Notch1 might regulate the NF-κB pathway through Asb2α. Methods: The study involved down-regulation of Notch1 in T-ALL cell lines (CCRFCEM cells and MOLT-4 cells) through treatment with gamma-secretase inhibitor (GSI) as well as the modulation of Asb2 in CCRF-CEM cells and MOLT-4 cells through transduction with lentivirus carrying Asb2 or Asb2-shRNA. Experiments using real-time PCR, western blot and co-immunoprecipitation were performed to evaluate the expression levels of related genes. Cell proliferation and apoptosis were measured while the expression of Asb2 was enhanced or inhibited. Results: Here, we demonstrated for the first time that Notch1 can activate the transcription of Asb2α, which then stimulates activation of NF-κB in T-ALL cells. Asb2α exerts its effects by inducing degradation and dissociation of IκBα from NF-κB in T-ALL cells. Moreover, specific suppression of Asb2α expression can promote apoptosis and inhibit proliferation of T-ALL cells. Conclusion: Notch1 modulates the NF-κB pathway through Asb2α, indicating that Asb2α inhibition is a promising option for targeted therapy against T-ALL.
The external loads and structural ultimate strength are two important aspects for the safety of ship hull girder. It may collapse in case the structural capacity is less than the external forces in extreme seas. In the present research, progressive collapse test is performed to investigate the collapse mechanism of ship structure in waves. External load with time history and corresponding structural collapse behavior are measured and discussed to demonstrate the interaction of fluid and structures
In this study, tri-butyl-phosphate (TBP)-kerosene is used as the extraction solvent to remove phenols from coal gasification wastewater, and the complex mechanism of the extraction is investigated. An effect experiment is conducted to determine the complex structures, the enthalpy change of reaction, and the effect of extraction solvent concentration and temperature on the distribution coefficient. To predict the extraction effect before the experiment, the distribution coefficient mathematical model of phenol extraction is established, which is based on a liquid-liquid extraction model and verified for accuracy by the experiment. The effect experiment result shows that with an increase in concentration of TBP and decrease in temperature, the extraction distribution coefficient increases and further determines the complex structures and the enthalpy change of the reaction. Meanwhile, a comparison of experimental and calculated values in the model experiment result shows that the average relative error of extraction distribution coefficient is 5.56% in different concentrations of TBP and 2.72% in different temperatures. Considering the error of the experiment, this work concludes that the distribution coefficient mathematical model of phenol extraction has a high predictive effect on the distribution coefficient and extraction rate of volatile phenol in actual wastewater.
It will be a new approach that BIM’s capital project lifecycle management (CPLM) applied to the yacht industry. This paper explored the feasibility of applying the principles and rationales of BIM for capital project lifecycle management in luxury yacht design, engineering, fabrication, construction and operation. The paper examined the premises and backbone technology of BIM. It then evaluated leading naval engineering and shipbuilding software applications and their development trends from the functional lens of BIM. To systematically investigate a BIM-based approach for capital project lifecycle management (CPLM) in the luxury yacht industry, the paper proposed and outlined an implementation framework. A case study and a student competition use case were discussed to delineate the core constituents and processes of the proposed framework. The case of BIM was reviewed. Through the domestic custom luxury yacht design and prototyping student competition, the application of this framework in educational research is demonstrated and the initial quantitative assessment of the framework is carried out. Conclusions: a BIM-based CPLM implementation framework can help the luxury yacht industry capitalize on the global transformation to an information-centric and data-driven new business paradigm in shipbuilding with integrated design, manufacturing and production
In order to effectively promote the construction of the Yangtze River economic belt, it has become China’s national strategy to vigorously develop the river-sea-going transportation. In the present paper, theoretical analysis, numerical simulation and model test are combined together to develop f lat-type river-sea-going ship which is characterized with larger loading capacity, lower fuel consumption, better performance on energy-saving and environmental-friendly, excellent economy and higher transportation efficiency. Key technologies on hydrodynamic performance, structural safety, energy-saving technology and green ship technology are investigated to develop the river-sea-going ship. The developed “4E” level ship has great significance to the implementation of national strategic deployment
The Hexi Corridor is the most important area for desert oasis farming in northwestern China. Due to persistent drought and water shortage, sewage irrigation is widely used in this area. Heavy metal pollutants contained in the sewage could remain in the surface layer of agricultural soil and accumulate in plants. Our research used pot experiments to evaluate carrot crop (Daucus carota L.) production, heavy metal uptake, and bioavailability under single cadmium (Cd) or nickel (Ni) contamination and compound (Cd-Ni) contaminations in irrigated desert oasis soil. The results show that Cd existed in the Fe-Mn oxide bound fraction and Ni presented in the residual fraction mainly in original (control) soils. Low concentrations of Cd could promote the growth of carrots, while high concentrations of Cd significantly restrain the growth of the crops. However, Ni had a poisonous effect on the carrots even at the lowest concentrations. There was an antagonistic effect between Cd and Ni in the compound contaminated oasis soils. The bio-concentration factors (BCF) of Cd in carrots were higher than those of Ni, and the BCF of Cd and Ni in single-contaminated soils were higher than those in compound-contaminated soils. Cd and Ni contents in different parts of the carrots were correlated with the exchangeable fraction in contaminated oasis soils, which would cause potential risk to human health through the food chain.
In recent years, with the rapid economic development of Bohai Economic bay area in China, the atmospheric environmental pollution problem has been of wide concern and has attracted great public attention. In this paper, the data of PM₁₀, SO₂, CO, NO₂, O₃ and PM₂.₅ in 12 cities located around the Bohai Bay area of China were collected in 2016. These 12 cities were divided into coastal and non-coastal areas according to distance from the sea. On the basis of data analysis, the air quality pollution and its distribution in the bay area were researched. The results indicated that the rates failing to comply with National Ambient Air Quality Standard (NAAQS) of PM₂.₅ were 6.39% and 34.15% in coastal cities and non-coastal cities, respectively, and the noncompliance rates of PM₁₀ were 12.84% and 28.96%, respectively, with O₃ exceeding 23.50% and 31.69%, respectively, and non-coastal cities were higher than the coastal cities. If complying with WHO’s concentration limit of PM₂.₅ (10 μg/m³), the number of noncompliance days is 7.4 times as high as that of NAAQS, and some cities could even not meet the standard throughout the year. There are significant differences between PM₂.₅ in coastal cities and non-coastal cities due to the air mass and its own industrial differences, while the difference on O₃ is not significant due to similar sources of pollution in the bay area. The pollution situation in the bay area showed that PM₂.₅ had heavy pollution in January, March, November and December, while the atmosphere in July, August and September was the least polluted and did not show the “weekend effect” due to the effects of the local economy. On the whole, there is still a serious problem of air pollution in the Bohai Bay area.
Microtoid cricetids are widely considered to be the ancestral form of arvicoline rodents, a successful rodent group includ− ing voles, lemmings and muskrats. The oldest previously known microtoid cricetid is Microtocricetus molassicus from the Late Miocene (MN9, ca. 10–11 Ma) of Europe. Here, we report a new microtoid cricetid, Primoprismus fejfari gen. et sp. nov., from the Junggar Basin of Xinjiang, northwestern China. The rodent assemblage found in association with this specimen indicates a late Early Miocene age, roughly estimated at 18–17 Ma, and thus more than 6 million years older than M. molassicus. While morphological comparisons suggest that the new taxon is most closely related to M. molas− sicus, it differs from the latter in a striking combination of primitive characters, including a lower crown, smaller size, a differentiated posterolophid and hypolophid, a faint anterolophid, the absence of an ectolophid, and the presence of a stylid on the labial border of the tooth. Arid conditions prevailing across the mid−latitude interior of Eurasia during the Early Miocene, enhanced by the combined effects of the Tibetan uplift and the gradual retreat of the Tethys Ocean, likely played a role in the appearance of grasslands, which in turn triggered the evolution of microtoid cricetids and, ultimately, the origin of arvicoline rodents.
Nansi Lake, a typical shallow and macrophyte-dominated lake in south Shandong Province, China, has a total surface area of 1,266 km2 and is the largest and most important freshwater reservoir in northern China for the eastern route of the South-North Water Diversion (SNWD) project, in which the water in Yangtze River will be transported more than 1,100 km from Yangzhou to Tianjin and Beijing. A water-level fluctuating zone (WLFZ) near Nansi Lake will be formed when the SNWD project begins to transport water flowing through the lake. Phosphorus fractions and adsorption-release characterization for soil samples from four typical lands (reed, wood, maize, and soybean) were conducted to investigate soil phosphorus stability. In addition, a soil submerged experiment was performed to simulate phosphorus release under submerged conditions. Phosphorus adsorption-desorption equilibrium concentrations (CEPC) of four lands were 0.006, 0.089, 0 .110, and 0.287 mg L-1, respectively, which means that maize, soybean, and woodland had higher potentials than reed land for phosphorus releasing to the overlaying water. Submerged experiment results showed that the quantities of p hosphorus released from reed, wood, maize, and soybean soils were -0.14, 0.06, 0.12, and 0.97 mg kg-1, respectively. Soils in the reed land adsorbed phosphorus from overlying water, but the other soils released phosphorus into the water. Thus, in order to decrease the phosphorus releasing quantity from the wood, soybean, and maize land under the conditions of submerged lands at water diversion time, the land uses of wood, soybean, and maize should be switched to land for planting reed.
The air pollution index (API) and meteorological parameters in four cities (Harbin, Changchun, Shenyang, and Dalian) in north-eastern China were analyzed in 2001-12, to study the characterization of the API and its influential factors. According to the monitoring data, air pollution is a significant problem in northeastern China, with all four industrial cities heavily polluted, especially Shenyang. During the study period, the API in the cities was down slightly. Clear interannual, seasonal, and monthly variations of air pollution were determined, which indicated that air quality was poorest in winter (especially November and December), but improved in summer (especially July and August). Air quality level varied in different weather conditions. Water vapor pressure was the most influential meteorological factor with regard to the API, followed by air temperature and surface pressure. Wind direction was found to be an important influential factor with regard to air pollution, because air flow from different directions has an impact on the accumulating or cleaning process of pollutants. However, the dominant meteorological factors influencing air pollution varied in each of the cities in terms of season, time scale, and level of air pollution. Our results highlight the significant impact of synoptic weather on API in northeastern China.
Safflower varieties were commonly divided into high, low and middle linoleic acid (LA) types according to their LA relative percentage contents in the seed oil. Fatty acid desaturase 2 (FAD2) plays a key role for LA content in seed. The sequence variations of FAD2 (CtFAD2-2, CtFAD2-10, CtFAD2-11) genes which could express in developmental seed of safflower were analyzed in 15 different LA-type materials. The results revealed that the CtFAD2-2 sequences were the same in all materials, and the CtFAD2-10, CtFAD2-11 sequences formed into two haplotypes independent of the LA-type of safflower seed. Yeast expression analysis revealed that two haplotypes of CtFAD2-10 had the function of oleic acid desaturase. The real-time PCR analysis of FAD2 in high and low LA-type materials at different seed developmental stages revealed that CtFAD2-2, CtFAD2-10 and CtFAD2-11 expressed mainly at 10 days after flower (DAF) for two different LA-type materials and the accumulation of few mRNA was detected in 14–22 DAF. The expression pattern of CtFAD2-1 in two different LA-type safflower materials was significantly divergent. For high-LA type, the accumulation of CtFAD2-1 mRNA was extremely low in 10 DAF, and its expression level increased sharply between 14 and 18 DAF and decreased slightly after 18 DAF. For low-LA type, the accumulation of CtFAD2-1 mRNA was extremely low during seed development stages. In conclusion, the gene structure and expression level of CtFAD2-1 may be the main factor affecting the differentiation of LA-type for safflower materials.
Community surveys were performed in 30 forest stands with similar conditions under different management types in forests of northeastern China to study the influence of forest management on plant biodiversity. We evaluated this effect by calculating and analyzing species richness, vegetation structure, and aboveground biomass. Large variations in species composition, vegetation structure, species richness, and aboveground biomass were evident among the three types of common management types investigated (cut shrub tending, selective cutting, and understory planting). The species composition of the herb layer changed more than that of the shrub layer, and herbs were more vulnerable to impact from human activities. Each management type reduced the plant coverage, and this was most significant in planted plots. We found that in the cut shrub tending plots, the shrub height increased over time. The mean fresh weight of the control group was about 2 kg·m-2, which was about two-fold the selective cutting group (1 kg·m-2) and five-fold the understory planting group (0.4 kg·m-2). Our results also showed that management types in mixed forest stands strongly impact species diversity and, to some extent, environmental capacity, with negative effects on biodiversity.
Genetic differences between 20 Chinese wheat (Triticum aestivum L.) landraces highly resistant to Fusarium head blight (FHB) and 4 wheat lines highly susceptible to FHB were evaluated by means of microsatellite markers, in order to select suitable parents for gene mapping studies. Thirty-nine out of 40 microsatellite markers (97.5%) were polymorphic among the 24 wheat genotypes. A total of 276 alleles were detected at the 40 microsatellite loci. The number of alleles per locus ranged from 1 to 16, with an average of 6.9 alleles. Among these microsatellite loci, the largest polymorphism information content (PIC) value was 0.914 (GWM484), while the lowest PIC value was 0 (GWM24). The mean genetic similarity index among the 24 genotypes was 0.419, ranging from 0.103 to 0.673. Clustering analysis indicated that the highly susceptible synthetic wheat line RSP was less genetically related to and more divergent from the Chinese highly resistant landraces. These results were useful in the identification of suitable parents for the development of mapping populations for tagging the FHB resistance genes among these Chinese wheat landraces.
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