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1

Edukacja przyrodniczo-leśna ważnym zadaniem dla leśnych kompleksów promocyjnych w dobie reformy polskiego szkolnictwa

100%
Gajek J.
Studia i Materiały Centrum Edukacji Przyrodniczo-Leśnej
|
2002
|
tom 04
|
nr 1[6]
2

Zoohigieniczna ocena warunków utrzymania niosek Tetra-SL w kurnikach fermowych typu "Gostyń"

63%
Dobrzanski Z., Gajek J.
Medycyna Weterynaryjna
|
1983
|
tom 39
|
nr 09
3

Modyfikacja wlasna metody Seldingera wprowadzania cewnika do zyly szyjnej wewnetrznej

45%
Noszczyk-Nowak A., Paslawska U., Skrzypczak P., Gajek J., Zysko D.
Magazyn Weterynaryjny
|
2006
|
tom 15
|
nr 06
44-46
4

Przyczyny i diagnostyka omdlen

45%
Paslawska U., Zysko D., Gajek J., Noszczyk-Nowak A., Nicpon J.
Medycyna Weterynaryjna
|
2005
|
tom 61
|
nr 03
253-256
5

Analiza przypadkow klinicznych psow z kardiogennymi omdleniami

45%
Paslawska U., Noszczyk-Nowak A., Zysko D., Gajek J., Nicpon J.
Medycyna Weterynaryjna
|
2006
|
tom 62
|
nr 01
55-58
In recent years we have observed an increasing number of cases of fainting in dogs. These cases were investigated in the cardiological surgery at the Clinic of Horse, Dog and Cat Diseases at the Faculty of Veterinary Medicine of the Agricultural University in Wroclaw. The aim of the conducted research was to determine which heart diseases were the most frequent reason for fainting in dogs, what were the breed preferences and what diagnostic methods allowed for the diagnosis of the cardiogenic background of fainting. The research comprised 168 dogs, the patients of the cardiological surgery of the Clinic of Horse, Dog and Cat Diseases in the years 1996-2004. There were dogs of different breeds, both sexes, aged from 2 months to 14.5 years and weighing from 2 to 63 kg. The dogs with a different basic disease or where liver insufficiency or epilepsy were diagnosed, were excluded from the examined group. The most frequent reasons for fainting are bradycardia, tachycardia and atrio-ventricular blocs, as well as organic heart disorders: dilated cardiomiopathy in large breeds and endocardiosis in small and miniature breeds. Fainting appears most frequently in boxers, dachshunds and mixed breeds up to 20 kg. The most useful diagnostic methods of fainting comprise: resting ECG, along with the vagus nerve stimulation test, 24-hour Holter ECG monitoring and echocardiography.
6

Badanie EKG metoda Holtera jako metoda diagnostyki etiologii omdlen u psow

45%
Paslawska U., Zysko D., Gajek J., Noszczyk-Nowak A., Nicpon J.
Medycyna Weterynaryjna
|
2005
|
tom 61
|
nr 11
1256-1258
7

Przewlekła tachykardiomiopatia świń, jako nowy model do badań nad niewydolnością serca u człowieka

39%
Noszczyk-Nowak A., Gajek J., Pasławska U., Zysko D., Skrzypczak P., Nicpon J.
Prace i Materiały Zootechniczne
|
2008
|
tom 66
8

Przerost serca wyzwalany podaniem L-tyroksyny per os u rosnacych swin

39%
Noszczyk-Nowak A., Paslawska U., Zysko D., Gajek J., Nicpon J., Rabczynski J., Skrzypczak P.
Medycyna Weterynaryjna
|
2007
|
tom 63
|
nr 01
113-117
The aim of the experiment was to evaluate the influence of oral administration of L-thyroxine on the heart. The research material included 8 pigs of the polska bia³a zwis³oucha breed. The experimental hyperthyroidism was induced by oral administration of L-thyroxine at a dose 20 µg/kg b.w. in 4 pigs. The echocardiography examination was carried out 3 times in each pig: before hyperthyroidism outset and twice in hyperthyroxinemia. Through echocardiographic examination a statistically significant increase in LWd was stated. An increase in IVSd, decrease in LVd and a statistically significant increase in relative wall thickness and left ventricular mass in the group of pigs administered L-tyroxine was observed. A statistically significant decrease in SF connected with an increase in the left ventricle wall thickness occurred as well. The performed autopsy revealed an increased thickness of the right and left heart ventricles in swine with the experimental hyperthyroidism. It was stated that hyperthyroxinemia induces heart muscle hypertrophy which concerns mainly the ventricular muscles. Observed secondary hypertrophic cardiomyopathy may be the consequence of hyperthyroxinemia.
9

Komorowe zaburzenia rytmu jako wyraz zmian przewodzenia w doświadczalnej hipertyroksynemii

39%
Noszczyk-Nowak A., Gajek J., Paslawska U., Zysko D., Skrzypczak P., Nicpon J.
Prace i Materiały Zootechniczne
|
2008
|
tom 66
10

Migotanie przedsionkow u psow

39%
Noszczyk-Nowak A., Paslawska U., Zysko D., Gajek J., Nicpon J., Hebel M.
Medycyna Weterynaryjna
|
2008
|
tom 64
|
nr 05
686-689
Atrial fibrillation is one of the commonest arrhythmia in dogs and humans. It accompanies organic heart diseases but also other pathologies, e.g. hyperthyroidism. The aim of the study was to determine the frequency of the occurrence of atrial fibrillation, its potential causes and the relationship between electrocardiographic changes and other results of cardiological examination in dogs with this arrhythmia. From 1456 dogs referred to cardiological examination in the years 2001-2006, 521 dogs (35.78%) demonstrated arrhythmias. Atrial fibrillation was detected in 51 dogs, which accounts for 3.5% of all the examined dogs and 9.7% of the dogs with arrhythmias. In 49 cases atrial fibrillation was permanent. The mean age of all the examined dogs was 7.55 ± 3.6. However, it was significantly higher in the animals from II group (10.64 ± 3) as compared to those of I group (6.6 ± 3.2). Atrial fibrillation is dominant in dogs with a body weight exceeding 25 kg, which accounted for 72.55% of the examined group and are predisposed to dilated cardiomyopathy. Permanent atrial fibrillation is a common arrhythmia in dogs and it is accompanied by ventricular tachycardia, regardless of the etiology of the atrial fibrillation. Paroxysma atrial fibrillation is a very rare arrhythmia in dogs. Atrial fibrillation tends to occur in large breed dogs more frequently in the course DCM than in small dogs.
11

Nadkomorowe zaburzenia rytmu serca w przebiegu doświadczalnej hipertyroksynemii u świń, jako modelu dla człowieka

39%
Noszczyk-Nowak A., Gajek J., Paslawska U., Zysko D., Skrzypczak P., Nicpon J.
Prace i Materiały Zootechniczne
|
2008
|
tom 66
12

Objawy kliniczne, parametry hematologiczne i biochemiczne krwi u swin w przebiegu eksperymentalnej nadczynnosci tarczycy

39%
Noszczyk-Nowak A., Paslawska U., Skrzypczak P., Nicpon J., Gajek J., Zysko D.
Medycyna Weterynaryjna
|
2007
|
tom 63
|
nr 02
219-223
The aim of the study was to determine changes in the clinical image and biochemical and hematological blood parameters in pigs during the course of experimental hyperthyroidism. The research material included 10 pigs of the Wielka Bia³a Zwis³oucha breed. Experimental hyperthyroidism was produced by administering oral L-thyroxin at a dose of 20 µg/kg m.c. 1× day in 5 pigs for 8 weeks. The blood for biochemical and hematological investigations (AST, ALT, urea, creatinine, Na⁺, K⁺, Ca⁺⁺, Cal˙, Mg⁺⁺, TSH, FT₃, FT₄) was collected 4 times from the ear’s vein. Changes in swine behavior were observed: increase mobility, rapid tiredness and aggression. Hyperthyroidism caused a statistically significant increase in weight, temperature and heart rate and there was also a statistically significant increase in the amount of creatinine in blood plasma and thyroid hormone activity. There were no statistically significant biochemical and hematological blood parameters in either of the groups of swine.
13

Paroxysmal atrial arrhythmias as a cause of syncope in a Boxer dog - a case report

39%
Noszczyk-Nowak A., Gajek J., Paslawska U., Rabczynski J., Slawuta A., Nicpon J.
Bulletin of the Veterinary Institute in Puławy
|
2008
|
tom 52
|
nr 1
The aim of the presented electrophysiological and histological study was the investigation of unexplained syncopal spells in a dog of Boxer breed. The dog underwent non-invasive procedures, which turned out to be insufficient for a complete diagnosis. Invasive procedures showed paroxysmal atrial fibrillation. In post-mortem examination, intensive extravascular fibrosis in the both atria, mostly in the endocardium, as well as a local loss of the cross-striation in cardiomyocytes, the presence of giant nuclei, and penetration of adipose tissue, especially in the left ventricle, were found. These changes might be the cause of arrhythmias. Paroxysmal atrial arrhythmias can be the mechanism of syncope in dogs. The electrophysiological properties of the myocardium predispose to both supraventricular and ventricular arrhythmias in dogs. Invasive electrophysiological study is a valuable diagnostic tool in dogs with syncope.
14

Arrhythmias in programmed electrical stimulation in the course of experimentally induced hyperthyroidism in an animal model

39%
Noszczyk-Nowak A., Gajek J., Paslawska U., Skrzypczak P., Zysko D., Nicpon J.
Bulletin of the Veterinary Institute in Puławy
|
2008
|
tom 52
|
nr 1
To determine changes in physiological parameters of the myocardium in experimentally induced hyperthyreosis in an animal model, the occurrence and type of arrhythmias triggered during programmed electrical stimulation and changes in electrophysiological parameters of ventricular cardiomyocytes with hypertrophy due to hyperthyreosis were investigated. Hyperthyreosis was induced experimentally in five pigs, which were orally administered L-thyroxine at a dose of 20 µg/kg. Five untreated pigs served as the control. Programmed electrical stimulation was performed before administration of L-thyroxine (EPS 1), four (EPS 2) and eight (EPS 3) weeks after the onset of thyroxine administration, and four weeks after drug withdrawal (EPS 4). After the last stimulation, the animals were sacrificed and necropsied, with particular regard to heart autopsy. During the EPS 2, VERP was decreased in the group treated with the hormone (P<0.05). The mean values of AERP and AVNERP in the group were decreased as well. Atrial flutter and atrial fibrillation were induced during stimulation of the experimental group. In the other pigs of the experimental group, singular and paired ventricular extrasystolic were observed. In the EPS 3, AERP and AVNERP were statistically shorter in pigs with hyperthyreosis. A significant difference in Wenckebach CL between the control and experimental groups were observed. SNRT was shorter in the group with hyperthyreosis. In all pigs with hyperthyreosis, atrial fibrillation was induced. In one pig, non-sustained ventricular tachycardia was observed. During EPS 4, AERP remained shorter in group with hyperthyreosis. In two pigs of the group, atrial fibrillation was induced during pacing, and in two pigs, ventricular fibrillation was observed. The assessment of the heart's weight revealed a significant increase in its mass in pigs with hyperthyreosis. An increase in the thickness of the right and left ventricle free walls (P<0.01) and interventricular septum (P<0.01) was found in pigs with hyperthyreosis. At the same time, the inner diameter of the left ventricle was significantly smaller in this group (P<0.01) due to a concentric hypertrophy of the ventricle. In view of these findings, experimental hyperthyreosis caused shortening of refractory periods of different parts of the conducting system and enhanced susceptibility to supraventricular and ventricular arrhythmias, both spontaneous and induced during electrical stimulation. The mechanism of these arrhythmias can differ as a consequence of the hypertrophy of the left ventricle.
15

Preliminary observations of the effect of short time experimental ventricular tachycardia on glucose and insulin levels in pigs. A preliminarry communication

39%
Noszczyk-Nowak A., Skrzypczak P., Gajek J., Paslawska U., Zysko D., Nicpon J.
Bulletin of the Veterinary Institute in Puławy
|
2008
|
tom 52
|
nr 2
The aim of the research was to determine whether short-time heart muscle ischemia caused by fast ventricular pacing rate (ventricular tachycardia) provokes insulin and glucose blood level alterations and if so, how long those changes last after return to the physiological heart rate and restoration of proper heart muscle perfusion as well. It was stated that short-lasting tachycardia provoked by fast, forced ventricle rate, with no damage on the cardiac muscle resulted in significant fall of the glucose and insulin blood levels. The glucose returned to its initial level several minutes after heart rate normalisation; however, the insulin drop maintained for more than 10 min.
16
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Effect of short-term rapid ventricular pacing followed by pacing interruption on arterial blood pressure in healthy pigs and pigs with tachycardiomyopathy

27%
Skrzypczak P., Zysko D., Paslawska U., Noszczyk-Nowak A., Janiszewski A., Gajek J., Nicpon J., Kiczak L., Bania J., Zacharski M., Tomaszek A., Jankowska E. A., Ponikowski P., Witkiewicz W.
Polish Journal of Veterinary Sciences
|
2014
|
tom 17
|
nr 1
Ventricular tachycardia may lead to haemodynamic deterioration and, in the case of long term persistence, is associated with the development of tachycardiomyopathy. The effect of ventricular tachycardia on haemodynamics in individuals with tachycardiomyopathy, but being in sinus rhythm has not been studied. Rapid ventricular pacing is a model of ventricular tachycardia. The aim of this study was to determine the effect of rapid ventricular pacing on blood pressure in healthy animals and those with tachycardiomyopathy. A total of 66 animals were studied: 32 in the control group and 34 in the study group. The results of two groups of examinations were compared: the first performed in healthy animals (133 examinations) and the second performed in animals paced for at least one month (77 examinations). Blood pressure measurements were taken during chronic pacing - 20 min after onset of general anaesthesia, in baseline conditions (20 min after pacing cessation or 20 min after onset of general anaesthesia in healthy animals) and immediately after short-term rapid pacing. In baseline conditions significantly higher systolic and diastolic blood pressure was found in healthy animals than in those with tachycardiomyopathy. During an event of rapid ventricular pacing, a significant decrease in systolic and diastolic blood pressure was found in both groups of animals. In the group of chronically paced animals the blood pressure was lower just after restarting ventricular pacing than during chronic pacing. Cardiovascular adaptation to ventricular tachycardia develops with the length of its duration. Relapse of ventricular tachycardia leads to a blood pressure decrease more pronounced than during chronic ventricular pacing.
17

Technika implantacji sztucznego stymulatora serca u świni domowej w modelu przewlekłej niewydolności serca indukowanej tachykardią

27%
Janiszewski A., Paslawska U., Gajek J., Skrzypczak P., Noszczyk-Nowak A., Zosko D., Kiczak L., Bania J., Tomaszek A., Zacharski M., Nicpon J., Banasiak W., Jankowska E., Ponikowski P.
Annals of Warsaw University of Life Sciences - SGGW. Animal Science
|
2011
|
tom 48
18

P-R interval in porcine model of chronic tachycardia-induced cardiomyopathy

27%
Skrzypczak P., Zysko D., Paslawska U., Noszczyk-Nowak A., Janiszewski A., Kiczak L., Bania J., Zacharski M., Tomaszek A., Rybinska I., Nicpon J., Paslawski R., Gajek J., Jankowska E. A., Ponikowski P.
Bulletin of the Veterinary Institute in Puławy
|
2013
|
tom 57
|
nr 3
The aim of the study was to assess the atrioventricular conduction in the model of porcine pacing induced tachycardiomyopathy. Fifty-one swine were examined: 27 were paced and 24 served as a control group. Every 4 weeks, the animals were anaesthetised for 1 h and an ECG Holter was performed. Thirty minutes after the onset of anaesthesia, P-R and R-R intervals were measured. Each result was assigned to the subgroup according to the animal's weight and the presence or absence of previous pacing. P-R interval was longer in animals after at least 4 weeks of rapid ventricular stimulation than in adjusted group of the animals according to the body mass. Multivariate analysis has showed that longer P-R interval was related to male gender, higher body mass, slower heart rate, and history of previous pacing. Chronic ventricular pacing led to the slowing of atrioventricular conduction. The presence of differences in the duration of R-R intervals between groups was only found in swine weighing 120-139 kg. The R-R interval was shorter in paced animals, whereas PR interval was longer in that group, indicating that PR prolongation is related to electrical or structural remodelling of the cardiac conductive tissue but not increased sympathetic nervous system activity, which is expected to produce corresponding changes in PR and R-R intervals.
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