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Growth and fat deposition of dovekie chicks (Alle alle, alcidae)

100%
Konarzewski M.
Acta Physiologica Polonica
|
1988
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tom 39
|
nr 1
2

Przyczyny i skutki niejednoczesnego wylegu ptakow

100%
Konarzewski M.
Wiadomości Ekologiczne
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1997
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tom 43
|
nr 1
23-37
3

Przyszlosc miesa: przeslanie z naszej ewolucyjnej przeszlosci

100%
Konarzewski M.
Biuletyn Informacyjny. Instytut Zootechniki
|
2001
|
tom 39
|
nr 4
121-130
4

Mięso w diecie przyszłości: przesłanie z ewolucyjnej historii człowieka

100%
Konarzewski M.
Roczniki Instytutu Przemysłu Mięsnego i Tłuszczowego
|
2001
|
tom 38
|
nr Supl.1
5

Differentiation of analgesic and thermoregulatory mechanisms in mice selectively bred for magnitude of swim stress-induced analgesia (SSIA)

63%
Sadowski B., Konarzewski M.
Acta Neurobiologiae Experimentalis
|
1997
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tom 57
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nr 5
6

Prof.dr hab.Andrzej Myrcha [1939-1997]

63%
Konarzewski M., Taylor J. R. E.
Acta Ornithologica
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1997
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tom 32
|
nr 2
133-136
7

Spontaneous locomotor activity of mice divergently selected for basal and summit metabolic rates

63%
Konarzewski M., Gebczynski A.
Acta Neurobiologiae Experimentalis
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2007
|
tom 67
|
nr 3
8

Byc albo nie byc... malym

51%
Szafranska P. A., Zub K., Konarzewski M.
Kosmos
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2006
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tom 55
|
nr 1
75-82
9

Differences in behavior and brain plasticity of laboratory mice divergently selected for high and low metabolic rate

45%
Goncerzewicz A., Gorkiewicz T., Dzik J., Knapska E., Konarzewski M.
Acta Neurobiologiae Experimentalis
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2017
|
tom 77
|
nr Suppl.1
INTRODUCTION: Encephalization, i.e., the amount of brain mass related to an animal’s total body mass is increased in homeotherms comparing to ectotherms. A larger brain offers behavioral advantages, but also means energy expenditures that are an order of magnitude higher than in ectotherms. What are the benefits of larger, energetically expensive brains that allowed them to evolve? The ‘Expensive Tissue’ hypothesis links evolution of enlarged brain to increased cognitive skills that improve foraging performance. AIM(S): We aim at testing the ET hypothesis using two lines of mice bred for low and high basal metabolic rate (BMR). METHOD(S): Low (L-BMR) and high (H-BMR) lines of Swiss Webster mice were selected reaching 40% between-line difference in BMR. The weight of their internal organs, including the brain, their cognitive abilities and neural plasticity were measured. The cognitive abilities of the mice were tested in IntelliCage system which allows for assessment of learning of individual mice living in the social group. To test the brain plasticity-related differences between the lines we used a model of neural plasticity, CA3-CA1 hippocampal long-term potentiation (LTP). RESULTS: The weight of internal organs differed, with H-BMR mice organs being heavier. We found increased exploration of the environment in H-BMR mice, which also showed higher motivation to obtain the reward and faster learning of the reward’s position. In line with learning results, we found that LTP was induced at significantly higher level in H-BMR mice, suggesting higher neural plasticity in this line. CONCLUSIONS: Together, our results suggest that higher BMR is associated with more efficient exploration of the environment, higher motivation and better place learning. Increased cognitive skills, probably mediated by enhanced neuroplasticity, allow for improved foraging performance, in line with the ET hypothesis. FINANCIAL SUPPORT: Project is financed by the National Science Centre grant (NCN 2015/17/B/NZ8/02484).
10

Genetic correlation between analgesia, metabolism and thermoregulation in a cross between mouse lines with high and low pain sensitivity

33%
Sacharczuk M., Fedorowicz K., Konarzewski M., Lapo I., Lesniak A., Lipkowski A. W., Ragan A., Jaszczak K., Sadowski B.
Acta Neurobiologiae Experimentalis
|
2011
|
tom 71
|
nr 1
Exposure of an animal to stressful stimuli elicits a transient decrease in pain sensitivity, which often affects thermoregulatory mechanisms in the threatened organism. Briefly, we found that stress-induced analgesia (SIA) is inversely related to PMR (peak metabolic rate) and thermogenic capacity. This relationship was strong enough to permit the claim of an existence of a negative genetic correlation between SIA and PMR as well as thermogenesis. In the present study we performed a genome-wide quantitative trait locus (QTL) analysis in our mouse model established from outbred parental lines divergently selected for 60 generations for high- (HA line) or low- (LA line) swim stress-induced analgesia (SSIA) elicited by 3-min swim in 20°C water. The F2 population of 267 mice was used for the QTL analysis with 40 microsatellite markers distributed across the first five chromosomes. The analysis revealed significant QTLs SIA, for peak metabolism rate (PMR) and for hypothermia (Hyp). Some of these QTLs map to regions of known gene mutations influencing SIA, PMR and Hyp traits, moreover they map to regions of previously described QTLs and candidate genes. Apart from QTLs affecting single traits we identified QTLs common for examined traits (SIA-PMR-Hyp), (SIA-PMR), (SIA-Hyp) and (PMR-SIA) parameters, which explain phenotypic correlations between these traits.
11

Divergent selection of mice for high and low swim stress-induced analgesia alters polymorphism at microsatellite loci

33%
Fedorowicz K., Sacharczuk M., Konarzewski M., Lapo I., Kawka M., Sadowski B., Swiergiel A., Jaszczak K.
Animal Science Papers and Reports
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2007
|
tom 25
|
nr 4
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