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1

Torbiele jajnikowe u świń

100%
Szulanczyk-Mencel K., Mencel J.
Trzoda Chlewna
|
2008
|
tom 46
|
nr 02
2

Torbiele jajnikowe u swin

81%
Dubiel A., Szulanczyk K., Mencel J.
Magazyn Weterynaryjny
|
2007
|
tom 16
|
nr 06
38-40
3

IL-6 deficiency alters cognitive processes in mice

71%
Winnicka M., Bialuk I., Hryniewicz A., Mencel J., Kaminski K.
Acta Neurobiologiae Experimentalis
|
2009
|
tom 69
|
nr 3
Interleukin-6 (IL-6) in addition to its role in the immune system has the potential to modulate several brain functions including learning and memory processes. In the present study we investigated the role of IL-6 in CNS function in male mice not expressing IL-6 (C57BL/6J IL6-/-tm 1 Kopf) and wild type mice (WT) used as controls. The animals were kept in standard conditions with water and food available ad libitum except during experiments. All testing took place between 8.30 AM and 12.30 PM. Each group consisted of 13 animals. In order to evaluate a role of endogenous IL-6 in cognitive functions “object recognition test” for the evaluation of recognition memory was used. In an attempt to evaluate whether observed effect was memory specifi c, the level of anxiety and psychomotor activity of mice was evaluated in an “elevated plus maze” test and in an open fi eld, respectively. Recognition memory, measured by the difference in exploration of the new object and a duplicate of the familiar one, presented 1 h earlier, was impaired in IL-6 defi cient mice. Moreover, lack of IL-6 signifi cantly attenuated locomotor and exploratory activity measured in an open fi eld test and enhanced anxiety evaluated in an “elevated plus maze” test. Results of this study indicate that IL-6 defi ciency impairs recognition memory, attenuates locomotor and exploratory activity and enhances anxiety in mice. The study was supported by the Polish Ministry of Science grant Nr 2P05B01826.
4

Effect of a 4-week mental training on decrease in grasping force in young healthy people

61%
Kisiel-Sajewicz K., Siemiatycka M., Mencel J., Kaminski L., Marusiak J., Jaskolski A., Jaskolska A.
Acta Neurobiologiae Experimentalis
|
2019
|
tom 79
|
nr Suppl.1
INTRODUCTION: Not only muscle contraction, but also muscle relaxation plays an important role for performance of voluntary movements. Most of the studies have focused on muscle contraction rather than on their relaxation. Research on motor ability has established clearly that mental practice leads to improved execution of movement. AIM(S): Assessment of the effect of a four-week mental training on cortical activity related to decrease in grasping force in healthy, young people. METHOD(S): 15 healthy subjects (8 men and 7 women) between 23 to 33 years voluntarily participated in the study. Mental training (MT) lasted 4 weeks with 3 training sessions per week and cortical activity using 128‑channel EEG system was recorded in all subjects during two measurement sessions (before and after the MT). During sessions subjects performed: 3x maximal isometric voluntary contraction (MVIC) in grasp function, 40 repetitions at submaximal level of force (20% of MVIC) during the same task and 2 × MVIC. The amplitudes of motor related cortical potentials (MRCP) of the EEG signal were analyzed in the BESA software (BESA GmbH, Germany) for electrodes placed in the areas associated with the planning and execution of movements on averaged files from 20% MVIC part of the protocol and triggered around (from ‑3 s to 1 s) decrease in grasping force. To compare the MRCP values before and after MT, the Wilcoxon signed-rank test was performed in SPSS (IBM SPSS 22.0, USA) with the level of significant that was set at P≤0.05. RESULTS: Analysis of the MRCPs did show significant differences between relaxation amplitudes before and after the MT. CONCLUSIONS: Muscle relaxation is accompanied by activation of the premotor cortex (PM), primary motor (M1), primary and secondary somatosensory areas (S1, S2). The level of the cortical activity associated with relaxation of the muscles during precise grasp movement performed by right upper limb was higher after MT especially in the S1, S2 and PM areas compared to M1.
5

The magnitude of the movement-related cortical potentials during fast and slow voluntary knee extensor deactivation

61%
Kisiel-Sajewicz K., Siemionow V., Zhang L. D., Mencel J., Yue G. H., Jaskolska A., Jaskolski A.
Acta Neurobiologiae Experimentalis
|
2012
|
tom 72
|
nr 2
The aim of the study was to learn cortical signal characteristics for controlling voluntary deactivation of human skeletal muscles with different speeds. This study investigated whether MRCP measures for fast knee extensor (KE) deactivation were different from those for slow deactivation. Twenty-seven healthy volunteers (22.4 ± 4.5 years) participated in the study. They performed isometric KE contractions [2 sets (slow and fast) of 45 trials] using the right leg at a target level of 20% maximal voluntary contraction (MVC) force. In each trial, subjects held the force at the target for 10s after reaching it and then relaxed the force slowly (rate of force descending ~4% MVC/s) or as quick as possible to the baseline during fast set. Cortical signals for deactivating the muscles were quantified by estimating amplitude of the MRCP derived by force-triggered averaging of the 45-trial EEG data. Mapping of the MRCP based on data of the 128 channels was obtained to evaluate distribution of brain activity associated with slow and fast KE deactivation. MRCP controlling KE deactivation was significantly higher for fast than slow deactivation (P<0.05). A higher level of cortical activation is required for controlling fast muscles deactivation. These findings indicated that control of KE deactivation at the cortical level is modulated by a rate of force decrease. This could be related to a varied impact of feedback and feedforward mechanisms during slow and fast deactivation and this may result in differential corticospinal projections to the motoneuron pools of the synergist and antagonist muscles during both conditions. This work was supported in part by NIH 1T32 AR050959 and R01 NS 35130 grants, and Ministry of Science and Higher Education, Republic of Poland 10/MOB/2007/0 grant
6
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Moderate-intensity interval training increases serum brain-derived neurotrophic factor level and decreases inflammation in Parkinson's disease patients

61%
Zoladz J. A., Majerczak J., Zeligowska E., Mencel J., Jaskolski A., Marusiak J.
Journal of Physiology and Pharmacology
|
2014
|
tom 65
|
nr 3
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