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  1. 12 Folia Histochemica et Cytobiologica

  2. 8 Reproductive Biology

  3. 5 Folia Histochemica et Cytobiologica. Supplement

  4. 4 Folia Biologica

  5. 3 Journal of Physiology and Pharmacology

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Autorzy help

  1. 42 Slomczynska M.

  2. 11 Duda M.

  3. 8 Tabarowski Z.

  4. 7 Szoltys M.

  5. 5 Knapczyk-Stwora K.

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  1. 1 2020

  2. 1 2017

  3. 1 2016

  4. 2 2014

  5. 2 2012

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1

Xenoestrogens: mechanisms of action and some detection studies

100%
Slomczynska M.
Polish Journal of Veterinary Sciences
|
2008
|
tom 11
|
nr 3
263-269
Xenoestrogens are defined as chemicals that mimic some structural parts of the physiological estrogen compounds, therefore may act as estrogens or could interfere with the actions of endogenous estrogens. Two subtypes of the ER are known, the ERcc and ER ß, and both have a distinct tissue distribution and play a distinct role in physiology. Receptor dimmer assumes a distinctive conformation, binds to its estrogen response element (ERE), interacts with the general transcription complex bound to the TATA box within the respective gene promoter, and regulates gene transcription. The discovery and identification of co-activators and co-repressors provided crucial insights into the ER action. New evidence indicates that the activation of additional transcription factors as well as the action of xenoestrogens through estrogen receptors located outside the cell nucleus (in the plasma membrane, mitochondria and probably the cytosol) should be considered. The levels of exposition to xenoestrogens and the age of the investigated animal can have a significant effect on its development and reproduction. Therefore, several in vivo and in vitro assays have been developed to assess the estrogenic-like activity of individual compounds or natural mixtures. In this review, selected methods applied in physiological studies have been described. One of the most extensively used in vivo assays for estrogenicity is the rodent uterotrophic assay. In order to analyze the estrogenic properties of xenoestrogens, morphological, histological, biochemical and molecular studies should be introduced. A variety of in vitro tests have been established to determine estrogenic potency of xenoestrogens but even a combination of them is not able to predict their actual action in the organism. There is a need for the studies on all potential xenoestrogens to describe tissue-specific activities, and via which pathways in those tissues these compounds either disrupt or mimic hormone action.
2

Receptory hormonow steroidowych w jajniku swin

100%
Slomczynska M.
Postępy Biologii Komórki. Suplement
|
1999
|
tom 12
193-196
3

Dynamika rozmieszczenia receptorow hormonow steroidowych w jajniku.

100%
Slomczynska M.
Postępy Biologii Komórki
|
2002
|
tom 29
|
nr 1
27-46
4

Receptory hormonow steroidowych - budowa i funkcja

100%
Slomczynska M.
Postępy Biologii Komórki
|
1995
|
tom 22
|
nr 1
3-21
5

Immunocytochemical localization of steroid hormon receptors [AR, ER] and P450arom in developing porcine ovary

100%
Slomczynska M.
Folia Histochemica et Cytobiologica. Supplement
|
1997
|
tom 35
|
nr 2
6

The effect of phytoestrogens on the reproductive tract

100%
Slomczynska M.
Polish Journal of Veterinary Sciences
|
2004
|
tom 07
|
nr 3
Environmental estrogens may be derived from plants (phytoestrogens), pharmaceuticals or synthetic compounds. They exert estrogenic and/or potentially antiestrogenic effects on farm animals, wildlife and humans. Exposure to these compounds results in some abnormalities in the reproductive tract, changes in the estrous cycle, and possibly protection against the development of hormone- dependent cancer. The data obtained from animal studies suggest that the timing of exposure to phytoestrogens is important, and neonatal exposure causes the most pronounced effects.
7

The secretory activity of porcine ovarian cells in serum-free cultutes

63%
Jablonska A., Slomczynska M.
Folia Histochemica et Cytobiologica
|
1990
|
tom 28
|
nr 3
8

The cytoskeleton proteins and LH-regulated steroidogenesis of porcine luteal cells

63%
Gregoraszczuk E. L., Slomczynska M.
Folia Histochemica et Cytobiologica
|
1996
|
tom 34
|
nr 1
9

Localization of kappa opioid receptor in porcine granulosa cells

63%
Slomczynska M., Gregoraszczuk E.
Folia Histochemica et Cytobiologica. Supplement
|
1997
|
tom 35
|
nr 2
10

Immunohistochemical localization of androgen receptor [AR] in rat ovary

63%
Slomczynska M., Szoltys M.
Folia Histochemica et Cytobiologica
|
1997
|
tom 35
|
nr 2
11

Opioids as regulators of local function in the testis

63%
Bilinska B., Slomczynska M.
Folia Histochemica et Cytobiologica. Supplement
|
1996
|
tom 34
|
nr 1
12

Immunocytochemiczna lokalizacja histaminy w jajowodzie ptakow

51%
Hrabia A., Paczoska-Eliasiewicz H., Rzasa J., Slomczynska M.
Postępy Biologii Komórki. Suplement
|
1999
|
tom 12
125-128
13

Effects of testosterone and 2-hydroxyflutamide on progesterone receptor expression in porcine ovarian follicles in vitro

51%
Duda M., Durlej-Grzesiak M., Tabarowski Z., Slomczynska M.
Reproductive Biology
|
2012
|
tom 12
|
nr 4
14

Effects of transferrin on aromatase activity in porcine granulosa cells in vitro

51%
Durlej M., Duda M., Knapczyk K., Slomczynska M.
Folia Histochemica et Cytobiologica
|
2008
|
tom 46
|
nr 4
423-428
15

Prenatal exposure to antiandrogen flutamide affects androgen receptor (AR) expression in postnatal ovarian Development in Pig

51%
Durlej M., Wieciech I., Wegrzyn P., Slomczynska M.
Folia Biologica
|
2012
|
tom 60
|
nr 1-2
16

Tissue distribution of estrogen receptors alpha [ERalpha] and beta [ERbeta] in the pig embryo

51%
Knapczyk K., Duda M., Szafranska B., Slomczynska M.
Acta Biologica Cracoviensia. Series Botanica. Supplement
|
2006
|
tom 48
|
nr 1
53
17

Immunolocalization of cytochrome P450 17alpha-hydroxylase/c17-20 lyase in the ovary of pregnant pigs and fetal gonads

51%
Knapczyk-Stwora K., Sternak M., Durlej M., Slomczynska M.
Reproductive Biology
|
2011
|
tom 11
|
nr 2
18
Content available remote

Induction of autophagy in the porcine corpus luteum of pregnancy following anti-androgen treatment

51%
Grzesiak M., Knapczyk-Stwora K., Slomczynska M.
Journal of Physiology and Pharmacology
|
2016
|
tom 67
|
nr 6
19

Fitoestrogeny. 2. Wewnatrzkomorkowy mechanizm dzialania w ukladzie rozrodczym samicy

51%
Nynca A., Kraszewska O., Slomczynska M., Ciereszko R.
Postępy Biologii Komórki
|
2007
|
tom 34
|
nr 1
207-222
20

Luteal macrophage conditioned medium affects steroidogenesis in porcine granulosa cells

51%
Duda M., Knet M., Tabarowski Z., Slomczynska M.
Reproductive Biology
|
2011
|
tom 11
|
nr 2
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