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Molekularne mechanizmy przeciwnowotworowego dzialania czosnku . Rola reaktywnych form tlenu

100%

Debski B., Milner J. A.

Bromatologia i Chemia Toksykologiczna

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2007

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tom 40

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nr 3

223-228

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Increased postharvest peroxidase activity in selenium enriched mushrooms Agaricus bisporus

80%

Debski B., Milner J. A., Beelman R. B.

Żywienie Człowieka i Metabolizm

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2003

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tom 30

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nr 3-4

Edible mushrooms (Agaricus bisporus) were enriched with an irrigation solution containing or not fortified with selenium in form of sodium selenite. Se in control mushrooms was 1.04 mcg/g D.M. and in mushrooms subjected irrigations with water solution of Se this increased to 15 mg of Se/dm) after the first flush and rose to with subsequent flushes to 30.14 mcg/g D.M. Peroxidase activity offresh mushrooms was reduced in Se-enriched Agaricus bisporus. Postharvest storage Peroxidase activity increase for 6 days and then a depression in activity .occutred. A positive correlation between peroxidase activity and fruit body mass of mushrooms was observed. Following fractionation on Sephadex G-100 column 4 peaks of peroxidases activity was observed in water extracts of mushrooms regardless of Se treatment. Molecular mass of these protein fractions were estimated by molecular mass markers as 82, 57, 45 and 22 kDa. Substantial part of peroxidase activity appears to originated from Se-dependent glutathione peroxidase.

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The influence of age and sex on selenium distribution and glutathione peroxidase activity in plasma and erythrocytes of selenium-adequate and supplemented rats

80%

Debski B., Zarski T. P., Milner J. A.

Journal of Physiology and Pharmacology

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1992

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tom 43

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nr 3

The experiment was performed on Sprague-Dawley male rats weighing 203, 103 and 53 g, and female 99 g. Animals were fed for 2 weeks a diet containing 0,1 and 2,0 ppm of Se (Na₂ SeO₃ added). It was observed that the daily Se intake per kg of BW is lowered with an increase in animals body weight. Se-supplementation caused a significant increase of Se content in plasma and red blood cells. The highest concentration of Se in plasma and in RBC was found in females. GSH-Px activity was higher in RBC of all male rats receiving a Se-supplemented diet, but not in females. In plasma these differences between Se-adequate and supplemented rats were significant in youngest male rats and in females. These results suggest that age and sex of rats affect the concentration of Se and GSH-Px activity in plasma and RBC of rats.

Ograniczanie wyników

1 Bromatologia i Chemia Toksykologiczna

1 Journal of Physiology and Pharmacology

1 Żywienie Człowieka i Metabolizm

3 Debski B.

3 Milner J. A.

1 Beelman R. B.

1 Zarski T. P.

1 2007

1 2003

1 1992

Molekularne mechanizmy przeciwnowotworowego dzialania czosnku . Rola reaktywnych form tlenu

Increased postharvest peroxidase activity in selenium enriched mushrooms Agaricus bisporus

The influence of age and sex on selenium distribution and glutathione peroxidase activity in plasma and erythrocytes of selenium-adequate and supplemented rats